Results 61 to 70 of about 508,264 (219)

GPI anchor biosynthesis in yeast: phosphoethanolamine is attached to the α1,4-linked mannose of the complete precursor glycophospholipid [PDF]

, 2017
Cells synthesize the GPI anchor carbohydrate core by successively adding N-acetylglucosamine, three mannoses, and phosphoethanolamine (EtN-P) onto phosphatidylinositol, thus forming the complete GPI precursor lipid which is then added to proteins ...
Benachour, Abdellah, Burda, Patricie, Canivenc-Gansel, Elisabeth, Conzelmann, Andreas, Imhof, Isabella, Reggiori, Fulvio   +5 more
core  

The angiotensin-converting enzyme (ACE) gene family of Anopheles gambiae [PDF]

, 2005
Background Members of the M2 family of peptidases, related to mammalian angiotensin converting enzyme (ACE), play important roles in regulating a number of physiological processes.
Burnham, S., Isaac, R.E., Lee, A.J., Shirras, A.D., Smith, J.A.   +4 more
core   +4 more sources

Infections with extracellular trypanosomes require control by efficient innate immune mechanisms and can result in the destruction of the mammalian humoral immune system [PDF]

, 2020
Salivarian trypanosomes are extracellular parasites that affect humans, livestock, and game animals around the world. Through co-evolution with the mammalian immune system, trypanosomes have developed defense mechanisms that allow them to thrive in blood,
Magez, Stefan, Obishakin, Emmanuel Tumininu, Pinto Torres, Joar Esteban, Radwanska, Magdalena   +3 more
core   +1 more source

Neuronal activation by GPI-linked neuroligin-1 displayed in synthetic lipid bilayer membranes.

Langmuir, 2005
We have characterized, in vitro, interactions between hippocampal neuronal cells and silica microbeads coated with synthetic, fluid, lipid bilayer membranes containing the glycosylphosphatidyl inositol (GPI)-linked extracellular domain of the ...
M. Baksh, Camin Dean, S. Pautot, Shannon DeMaria, E. Isacoff, J. Groves   +5 more
semanticscholar   +1 more source

Phospholipase PlcH is involved in the secretion of cell wall glycoproteins and contributes to the host immune response of Aspergillus fumigatus

mLife
Glycosylphosphatidylinositol (GPI) anchoring is one of the conserved posttranslational modifications in eukaryotes that attach proteins to the plasma membrane.
Jinbin Hao, Yin Guo, Hui Zhou, Haomiao Ouyang, Jinghua Yang, Wenxia Fang, Cheng Jin   +6 more
doaj   +1 more source

Cell wall composition and biofilm formation of azoles-susceptible and -resistant Candida glabrata strains [PDF]

, 2011
In the present study, three strains of Candida glabrata have been investigated to shed light on the mechanisms involved in azole resistance during adherence and biofilm formation.
Vitali, Alberto, Vavala, Elisabetta, Marzano, Valeria, Leone, Claudia, Castagnola, Massimo, Iavarone, Federica, Angiolella, Letizia   +6 more
core   +3 more sources

Strain and temperature dependent aggregation of Candida auris is attenuated by inhibition of surface amyloid proteins

The Cell Surface, 2023
Candida auris is a multi-drug resistant human fungal pathogen that has become a global threat to human health due to its drug resistant phenotype, persistence in the hospital environment and propensity for patient to patient spread.
Dhara Malavia-Jones, Rhys A. Farrer, Mark H.T. Stappers, Matt B. Edmondson, Andrew M. Borman, Elizabeth M. Johnson, Peter N. Lipke, Neil A.R. Gow   +7 more
doaj   +1 more source

Recombinant GPI-anchored TIMP-1 stimulates growth and migration of peritoneal mesothelial cells. [PDF]

, 2012
Mesothelial cells are critical in the pathogenesis of post-surgical intraabdominal adhesions as well as in the deterioration of the peritoneal membrane associated with long-term peritoneal dialysis.
Djafarzadeh, Roghieh, Goyal, Pankaj, Himmelein, Susanne, Nelson, Peter J., Noessner, Elfriede, Notohamiprodjo, Susan, Ribeiro, Andrea, Sauter, Matthias, Siess, Wolfgang, Sitter, Thomas, Wörnle, Markus   +10 more
core   +5 more sources

Evolutionary rate covariation is pervasive between glycosylation pathways and points to potential disease modifiers.

PLoS Genetics
Mutations in glycosylation pathways, such as N-linked glycosylation, O-linked glycosylation, and GPI anchor synthesis, lead to Congenital Disorders of Glycosylation (CDG).
Holly J Thorpe, Raghavendran Partha, Jordan Little, Nathan L Clark, Clement Y Chow   +4 more
doaj   +1 more source

Isolation and purification of glycosylphosphatidylinositols (GPIs) in the schizont stage of Theileria annulata and determination of antibody response to GPI anchors in vaccinated and infected animals

Parasites & Vectors, 2018
Background Tropical theileriosis is widely distributed from North Africa to East Asia. It is a tick-borne disease caused by Theileria annulata, an obligate two-host intracellular protozoan parasite of cattle.
Toktam Abbasnia, Ahmad Asoodeh, Gholamreza Habibi, Alireza Haghparast   +3 more
doaj   +1 more source