Results 61 to 70 of about 34,844 (152)

Erratum: A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor [PDF]

open access: yesNature, 1998
Robert D. Klein   +19 more
openaire   +1 more source

DETECTION AND FOLLOW UP OF PNH CLONE BY MEASURING CD55 AND CD59 EXPRESSION ON NEUTROPHILS

open access: yesZdravniški Vestnik, 2004
Background. Paroxysmal nocturnal haemoglobinuria (PNH) is an acquired clonal haematopoietic stem cell disorder characterised by intravascular haemolysis, bone marrow failure and increased tendency to thrombosis.
Uroš Mlakar, Darja Žontar
doaj  

A Novel Monoallelic ALG5 Variant Causing Late-Onset ADPKD and Tubulointerstitial Fibrosis

open access: yesKidney International Reports
Introduction: Monoallelic variants in the ALG5 gene encoding asparagine-linked glycosylation protein 5 homolog (ALG5) have been recently shown to disrupt polycystin-1 (PC1) maturation and trafficking via underglycosylation, causing an autosomal dominant ...
Elhussein A.E. Elhassan   +34 more
doaj   +1 more source

Apical membrane trafficking during regulated pancreatic exocrine secretion--role of alkaline pH in the acinar lumen and enzymatic cleavage of GP2, a GPI-linked protein.

open access: yesEuropean journal of cell biology, 1995
The GP2/THP family of glycosyl phosphatidylinositol (GPI)-anchored proteins is targeted to apical secretory compartments in polarized epithelial cells. We demonstrate in the rat exocrine pancreas that enzyme-mediated release of GP2 from acinar cell membranes represents a pH-dependent process regulated by bicarbonate secreted from ductular cells ...
S D, Freedman, H F, Kern, G A, Scheele
openaire   +1 more source

Lipid rafts: cell surface platforms for T cell signaling

open access: yesBiological Research, 2002
The Src family tyrosine kinase Lck is essential for T cell development and T cell receptor (TCR)* signaling. Lck is post-translationally fatty acylated at its N-terminus conferring membrane targeting and concentration in plasma membrane lipid rafts ...
TONY MAGEE   +4 more
doaj  

Paroxysmal nocturnal hemoglobinuria: pathophysiology, natural history and treatment options in the era of biological agents

open access: yesBiologics: Targets & Therapy, 2008
Antonio M Risitano, Bruno RotoliHematology, Department of Biochemistry and Medical Biotechnologies, Federico II University of Naples, ItalyAbstract: Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal non-malignant hematological disease characterized ...
Antonio M Risitano, Bruno Rotoli
doaj  

Diacylglycerol kinase-ε is required for the formation of GPI-anchored CD14 and the LPS-induced proinflammatory responses of macrophages. [PDF]

open access: yesCell Commun Signal
Hromada-Judycka A   +6 more
europepmc   +1 more source

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