Results 111 to 120 of about 22,632 (211)
17,β-estradiol inhibits hepatitis C virus mainly by interference with the release phase of its life cycle [PDF]
, 2016 Rationale & Aim: Estrogen and estrogen-mediated signalling protect from hepatitis C virus through incompletely understood mechanisms. We aimed to ascertain which phase(s) of HCV life cycle is/are affected by estrogens.
Barbaglia, Matteo N. +10 more
core +2 more sources
The Concise Guide to PHARMACOLOGY 2025/26: Nuclear hormone receptors
British Journal of Pharmacology, Volume 182, Issue S1, Page S242-S258, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +20 more
wiley +1 more source
Frontiers in Molecular Neuroscience, 2018 Genistein, 4′,5,7-trihydroxyisoflavone, is a major isoflavone in soybean, which is known as phytestrogen having known benefit to brain functions. Being a common phytestrogen, the possible role of genistein in the brain protection needs to be further ...
Etta Y. L. Liu +11 more
doaj +1 more source
Molecular targets of developmental exposure to bisphenol A in diabesity: a focus on endoderm-derived organs [PDF]
, 2016 Several studies associate foetal human exposure to bisphenol A (BPA) to metabolic/endocrine diseases, mainly diabesity. They describe the role of BPA in the disruption of pancreatic beta cell, adipocyte and hepatocyte functions. Indeed, the complexity of
Almeida, P. +7 more
core +1 more source
Receptores e função do estrógeno no sistema reprodutor masculino [PDF]
, 2009 A substantial advance in our understanding on the estrogen signaling occurred in the last decade. Estrogens interact with two receptors, ESR1 and ESR2, also known as ERα and ERβ, respectively.
Fernandes, Sheilla Alessandra Ferreira +7 more
core +2 more sources
Intra-Testicular Signals Regulate Germ Cell Progression and Production of Qualitatively Mature Spermatozoa in Vertebrates [PDF]
, 2014 Spermatogenesis, a highly conserved process in vertebrates, is mainly under the hypothalamic-pituitary control, being regulated by the secretion of pituitary gonadotropins, FSH and LH, in response to stimulation exerted by Gonadotropin Releasing Hormone (
Gilda Cobellis +6 more
core +2 more sources
Zhongshan Daxue xuebao. Yixue kexue ban, 2016 摘 要: 【目的】 研究GPR30在卵巢癌中的亚细胞定位及临床意义?【方法】 应用免疫组化技术检测我院2000-2010年的110例卵巢癌组织中GPR30的表达,分析GPR30与卵巢癌的临床病理特点的关系?同时应用流式分选技术和免疫荧光技术检测GPR30在卵巢癌的亚细胞定位? 【结果】 GPR30在62.7%的卵巢癌组织中表达,其中包括51例浆液性腺癌和4例黏液性腺癌中(P = 0.102)?肿瘤残余组(R1,33/45)中GPR30表达率高于无残留组(R0,34/65),具有统计学差异(P = 0 ...
doaj
Altered expression of aromatase, estrogen receptors and progesterone receptors in human leydig cell hyperplasia [PDF]
, 2015 Testicular function is regulated by pituitary hormones and also by paracrine and autocrine factors. A number of reports have pointed out the importance of estrogens and progesterone in male reproductive tract.
Calandra, Ricardo Saul +8 more
core +2 more sources
Aberrant STYK1 expression in ovarian cancer tissues and cell lines
Journal of Ovarian Research, 2009 Background Overexpression of STYK1, a putative serine/threonine and tyrosine receptor protein kinase has been shown to confer tumorigenicity and metastatic potential to normal cells injected into nude mice. Mutation of a tyrosine residue in the catalytic
Jackson Kesmic A +3 more
doaj +1 more source
GPR30 mediates anorectic estrogen-induced STAT3 signaling in the hypothalamus
Metabolism, 2014 Estrogen plays an important role in the control of energy balance in the hypothalamus. Leptin-independent STAT3 activation (i.e., tyrosine(705)-phosphorylation of STAT3, pSTAT3) in the hypothalamus is hypothesized as the primary mechanism of the estrogen-induced anorexic response.
Obin, Kwon +8 more
openaire +3 more sources