Results 121 to 130 of about 22,632 (211)
Neuroprotective Actions of Estradiol and Novel Estrogen Analogs in Ischemia: Translational Implications [PDF]
This review highlights our investigations into the neuroprotective efficacy of estradiol and other estrogenic agents in a clinically relevant animal model of transient global ischemia, which causes selective, delayed death of hippocampal CA1 neurons and ...
Adams +213 more
core +1 more source
Extra nuclear localization of steroid receptors and non genomic activation mechanisms [PDF]
Los receptores de hormonas esteroides han sido considerados históricamente como factores de transcripción nucleares. Sin embargo, en los últimos años surgieron evidencias que indican que su activación desencadena eventos rápidos, independientes de la ...
Bottino, Maria Cecilia +1 more
core
Associations between anxiety, body mass index, and sex hormones in women [PDF]
Background: Several studies have shown a positive association between anxiety and obesity, particularly in women. We aimed to study whether sex hormone alterations related to obesity might play a role in this association.
Bae, Y. +14 more
core +2 more sources
Estrogens and male reproduction [PDF]
n males, estrogens exert pleiotropic effects by acting on several tissue and organs, including the male reproductive system. The action of estrogens is manifest from prenatal life during which the exposure to estrogen excess might influence the ...
Carani, Cesare +5 more
core
Purpose: To investigate the effects of estrogen G protein-coupled receptor 30 (GPR30) agonist G1 on hippocampal neuronal apoptosis and microglial polarization in rat traumatic brain injury (TBI).
Meng-Xian Pan +4 more
doaj +1 more source
Intracellular Distribution and Involvement of GPR30 in the Actions of E2 on C2C12 Cells.
Fil: Ronda, Ana Carolina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnológico Bahia Blanca. Instituto de Ciencias Biologicas y Biomedicas del Sur; Argentina.
Ronda, Ana Carolina +1 more
openaire +3 more sources
The role of GRK2 in hypertension and regulation of GPR30 [PDF]
In the hypertensive state, the expression of G protein-coupled receptor kinase 2 (GRK2) level is elevated. On the other hand, the expression of GPR30, a recently discovered GPCR is greatly impaired. The current study focuses on investigating the roles of these two proteins in regulating G protein signaling under the normal and hypertensive states ...
openaire
Non-genomic actions of aldosterone: From receptors and signals to membrane targets. [PDF]
In tissues which express the mineralocorticoid receptor (MR), aldosterone modulates the expression of membrane targets such as the subunits of the epithelial Na(+) channel, in combination with important signalling intermediates such as serum and ...
Dooley, Ruth +2 more
core +1 more source
AMPK Phosphorylation Effect of Genistein Is Independent of GPR30 [PDF]
Sarai Vásquez-Reyes +6 more
openaire +1 more source
Cryo-EM structure of the bicarbonate receptor GPR30
G-protein-coupled receptor 30 (GPR30) is a bicarbonate receptor that plays a vital role in cellular responses to extracellular pH and ion homeostasis. Despite its significance, the mechanisms by which GPR30 interacts with bicarbonate ions remain elusive.
Shota Kaneda +6 more
openaire +1 more source

