Results 291 to 300 of about 29,098 (325)

Molecular Alterations in Ferroptosis and the Effects of Resveratrol: A Systematic Review. [PDF]

J Biochem Mol Toxicol
Dos Santos AB, Santos-Terra J, Carletti JV, Deckmann I, Gottfried C.   +4 more
europepmc   +1 more source

Mitochondria ATP Pro‐Ferroptosis by Adjusting the Conversion of PUFA to PUFA‐PLs

MedComm – Oncology, Volume 4, Issue 3, September 2025.
Glutamine deprivation can promote PUFA oxidation and PTGS2 expression through the upregulation of intracellular ROS, but not ferroptosis. Because glutamine deficiency exhausts mitochondrial ATP, thereby hinders the conversion of PUFA into their active form of PUFA‐CoA needed for lipid synthesis.
Chaoyi Xia, Lianchao Gao, Jingshu Min, Caiyun Fu   +3 more
wiley   +1 more source

<i>TRIP6/c-Fos</i> regulating <i>GPX4</i> modulates gastric cancer growth by inhibiting ferroptosis. [PDF]

J Gastrointest Oncol
Huang Y, Zhang W, Shen J, Li Y.
europepmc   +1 more source

Hydrogen Sulfide Protects Erectile Function Through Stimulation of Antioxidant Defense in the Corpus Cavernosum: Insights From SG1002 Administration and Cystathionine γ‐Lyase Knockout

The FASEB Journal, Volume 39, Issue 15, 15 August 2025.
Chronic consumption of a western diet suppressed corpus cavernosum cystathionine γ‐lyase (CSE) protein content and H2S production and was associated with elevated penile reactive oxygen species (ROS) levels and impaired erectile function. CSE knockout mice demonstrate impaired erectile function, elevated penile ROS levels, and suppressed corpus ...
Tooyib A. Azeez, Paige R. Rhein, Clifford J. Pierre, Colin M. Ihrig, Justin D. La Favor   +4 more
wiley   +1 more source

Irisin prevents liver injury during exhausting physical activity by suppressing ferroptosis via Nrf2/GPX4 signaling. [PDF]

BMC Gastroenterol
Li Z, Wang B, Li X.
europepmc   +1 more source

Quercetagetin alleviates liver fibrosis in non-alcoholic fatty liver disease by promoting ferroptosis of hepatic stellate cells through GPX4 ubiquitination. [PDF]

Chin Med
Qiu Y, Li S, Jiang M, Huang A, Yang Y, Chen X, Li H, Yang Z, Wei J, Xuan J.   +9 more
europepmc   +1 more source

Fucoxanthin Ameliorates Carbon Tetrachloride-Induced Liver Fibrosis in Mice via Nrf2/HO-1/GPX4-Mediated Ferroptosis Pathway. [PDF]

Food Sci Nutr
Liu Z, Ye J, Xi J, Li Q, Tang Y, Tian Y, Wang D, Yang Z, Ding Y.   +8 more
europepmc   +1 more source

Hsp90 C-terminal domain inhibition enhances ferroptosis by disrupting GPX4-VDAC1 interaction to increase HMOX1 release from oligomerized VDAC1 channels. [PDF]

Redox Biol
Li J, Wu G, Su H, Liang M, Cen S, Liao Y, Zhou X, Xie G, Deng Z, Tan W, Li Y, Xiao W, Liu L, Zhang J, Zheng Z, Deng Y, Huang Y, Shi X, Liu Y, Zhang G, Chen X.   +20 more
europepmc   +1 more source