Cytokines in Clinical and Experimental Transplantation [PDF]
Allograft rejection is a complex process, which requires interactions between different cell types and a variety of soluble factors, such as cytokines. In this review we discuss the role of cytokines in the induction and effector phases of the rejection ...
Savelkoul, Huub F. J.+1 more
core +7 more sources
Incidence of Rejection in Renal Transplant Surgery in the LVHN Population Leading to Graft Failure: 6 Year Review [PDF]
Incidence of Rejection in Renal Transplant Surgery in the LVHN Population Leading to Graft Failure: 6 Year Review Jessica Ludolph1 Lynsey Biondi, MD1,2 and Michael Moritz, MD1,2 1Department of Surgery, Lehigh Valley Health Network 2Research Scholar ...
Biondi, Lynsey S, MD+2 more
core +1 more source
Early post-transplant urinary IP-10 expression after kidney transplantation is predictive of short- and long-term graft function [PDF]
The early identification of renal transplant recipients at enhanced risk of developing acute and subclinical rejection would allow individualized adjustment of immunosuppression before functional graft injury occurs and would exclude these patients from ...
Babel, N.+9 more
core +1 more source
Gut microbes contribute to variation in solid organ transplant outcomes in mice [PDF]
© The Author(s), 2018. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Microbiome 6 (2018): 96, doi:10.1186/s40168-018-0474-8.Solid organ transplant recipients show ...
Alegre, Maria-Luisa+4 more
core +1 more source
Reduced CD40L expression on ex vivo activated CD4+T-lymphocytes from patients with excellent renal allograft function measured with a rapid whole blood flow cytometry procedure [PDF]
Background: The CD40-CD40L (CD154) costimulatory pathway plays a critical role in the pathogenesis of kidney allograft rejection. In renal transplant biopsies, CD4+ CD40L+ graft-infiltrating cells were detected during chronic rejection in contrast to ...
Friedrich, N.+5 more
core +1 more source
Alemtuzumab preconditioning with tacrolimus monotherapy - The impact of serial monitoring for donor-specific antibody [PDF]
BACKGROUND. Antibody preconditioning with tacrolimus monotherapy has allowed many renal allograft recipients to be maintained on spaced weaning. METHODS.
Adriana Zeevi+29 more
core +1 more source
The adverse impact on liver transplantation of using positive cytotoxic crossmatch donors [PDF]
Because of the liver graft's ability to resist cytotoxic antibody-mediated rejection, it has become dogma that the conventional transplant crossmatch used to avoid hyperacute rejection of other organs is irrelevant to the liver.
Abu-Elmagd, K+11 more
core +1 more source
The outcome of corneal transplantation in infants, children, and adolescents [PDF]
© 2011. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/OBJECTIVE: To examine factors affecting penetrating corneal graft survival and visual outcomes in patients aged less ...
Coster, Douglas John+3 more
core +1 more source
Comparative long-term evaluation of tacrolimus and cyclosporine in pediatric liver transplantation [PDF]
Background. In this report, we compare the long-term outcome of pediatric liver transplantation (LTx) patients maintained with tacrolimus-based and with cyclosporine (CsA)-based immunosuppressive therapy.
Fung, J+7 more
core +1 more source
The Current Status of Liver Transplantation. [PDF]
More than thirty patients have now undergone liver transplantation in Denver, some more than once, and survivals of up to two and a half years have been achieved. Through this and other experience it has been learned that graft viability is more critical
Starzl, Thomas E
core +1 more source