Results 41 to 50 of about 155,675 (375)

Mobilized Peripheral Blood Stem Cells Versus Unstimulated Bone Marrow As a Graft Source for T-Cell-Replete Haploidentical Donor Transplantation Using Post-Transplant Cyclophosphamide. [PDF]

, 2017
Purpose T-cell-replete HLA-haploidentical donor hematopoietic transplantation using post-transplant cyclophosphamide was originally described using bone marrow (BM).
Al Malki, Monzr M, Anasetti, Claudio, Argall, Trevor, Bashey, Asad, Ciurea, Stefan O, Eapen, Mary, Fasan, Omotayo, Fuchs, Ephraim Joseph, Gaballa, MD, Sameh, Hamadani, Mehdi, McCurdy, Shannon R, Munshi, Pashna, Nakamura, Ryotaro, O\u27Donnell, Paul V, Perales, Miguel-Angel, Raj, Kavita, Rocha, Vanderson, Romee, Rizwan, Rowley, Scott, Salit, Rachel B, Soiffer, Robert J, Solh, Melhem, St Martin, Andrew, Zhang, Mei-Jie   +23 more
core   +2 more sources

Optimized therapeutic strategy for patients with refractory or relapsed acute myeloid leukemia: long‐term clinical outcomes and health‐related quality of life assessment

Cancer Communications, Volume 42, Issue 12, Page 1387-1402, December 2022., 2022
Abstract Background Patients with refractory or relapsed acute myeloid leukemia (AML) have poor survival, necessitating the exploration of optimized therapeutic strategy. Here, we aimed to investigate clinical outcomes and health‐related quality of life (HR‐QoL) after total therapy, which included allogeneic hematopoietic stem cell transplantation ...
Chen‐hua Yan, Yu Wang, Yu‐qian Sun, Yi‐fei Cheng, Xiao‐dong Mo, Feng‐rong Wang, Yu‐hong Chen, Yuan‐yuan Zhang, Ting‐ting Han, Huan Chen, Lan‐ping Xu, Xiao‐hui Zhang, Kai‐yan Liu, Xiao‐jun Huang   +13 more
wiley   +1 more source

Review of Cutaneous Graft-vs-Host Disease

Actas Dermo-Sifiliográficas (English Edition), 2016
Graft-vs-host disease (GVHD) is a multisystem disease that arises as a complication of allogeneic hematopoietic stem cell transplant. It is due to recognition of the recipient's tissues by immune cells from the donor. The skin and mucous membranes are the organs most commonly affected.
J. Sanz-Caballer, Rafael Botella-Estrada, R. Ballester-Sánchez, Miguel Ángel Navarro-Mira   +3 more
openaire   +3 more sources

Vascular co‐option and vasculogenic mimicry mediate resistance to antiangiogenic strategies

Cancer Reports, Volume 5, Issue 12, December 2022., 2022
Abstract Background The concept that all the tumors need the formation of new vessels to grow inspired the hypothesis that inhibition of angiogenesis would have led to “cure” cancer. The expectancy that this type of therapy would have avoided the insurgence of resistance was based on the concept that targeting normal vessels, instead of the cancer ...
Francesco Pezzella, Domenico Ribatti
wiley   +1 more source

A Latent Space Model for HLA Compatibility Networks in Kidney Transplantation [PDF]

arXiv, 2022
Kidney transplantation is the preferred treatment for people suffering from end-stage renal disease. Successful kidney transplants still fail over time, known as graft failure; however, the time to graft failure, or graft survival time, can vary significantly between different recipients.
arxiv  

Optimizing Transplant Approaches and Post-Transplant Strategies for Patients With Acute Myeloid Leukemia

Frontiers in Oncology, 2021
Acute Myeloid Leukemia (AML) is the commonest indication for allogeneic stem cell transplantation (allo-SCT) worldwide. The increasingly important role of allo-SCT in the management of AML has been underpinned by two important advances.
Justin Loke, Justin Loke, Hrushikesh Vyas, Hrushikesh Vyas, Charles Craddock, Charles Craddock   +5 more
doaj   +1 more source

Macrophage regulation of graft-vs-host disease

World Journal of Clinical Cases, 2020
Hematopoietic stem cell transplantation has become a curative choice of many hematopoietic malignancy, but graft-vs-host disease (GVHD) has limited the survival quality and overall survival of hematopoietic stem cell transplantation. Understanding of the immune cells' reaction in pathophysiology of GVHD has improved, but a review on the role of ...
Xiaofan Li, Yaqun Hong, Bo Wan
openaire   +3 more sources

Extracorporeal Photopheresis in Pediatric Graft-vs-Host Disease

Actas Dermo-Sifiliográficas (English Edition), 2021
Extracorporeal photopheresis (ECP) is an immunomodulatory therapy used to treat graft-vs-host disease (GVHD) in adults and children. Few studies have examined its use in children.To describe demographic characteristics, clinical response, adverse effects, and outcomes in a series of pediatric patients with acute or chronic GVHD treated with ECP.We ...
M.L. Makiya, S.A. Bruey, K.Y. Cueto Sarmiento, J.A. Baquero Rey, Paula A Enz, Luis Daniel Mazzuoccolo, A. Andrade Miranda   +6 more
openaire   +4 more sources

Inflammatory Cytokine Networks in Gastrointestinal Tract Graft vs. Host Disease

Frontiers in Immunology, 2019
Graft vs. host disease (GVHD) is the major non-relapse complication associated with allogeneic hematopoietic stem cell transplantation (HSCT). Damage to the gastrointestinal (GI) tract from acute GVHD is a particularly serious event that can result in ...
Clint Piper, William R. Drobyski, William R. Drobyski   +2 more
doaj   +1 more source

Cell migration and chimerism after whole‐organ transplantation: The basis of graft acceptance [PDF]

, 1993
Improvements in the prevention or control of rejection of the kidney and liver have been largely interchangeable ( 1 , 2 ) and then applicable, with very little modification, to thoracic and other organs.
Demetris, AJ, Fung, JJ, Ildstad, S, Kocova, M, Murase, N, Nalesnik, M, Ramos, H, Ricordi, C, Rudert, WA, Starzl, TE, Todo, S, Trucco, M, Tzakis, A, Zeevi, A   +13 more
core   +1 more source