Results 1 to 10 of about 3,331 (249)
Phage therapy as a revolutionary medicine against Gram-positive bacterial infections [PDF]
Background Antibiotic resistance among pathogenic bacteria has created a global emergency, prompting the hunt for an alternative cure. Bacteriophages were discovered over a century ago and have proven to be a successful replacement during antibiotic ...
Archana Loganathan +5 more
doaj +5 more sources
Clinical update on linezolid in the treatment of Gram-positive bacterial infections
Sally Ager, Kate GouldDepartment of Microbiology, Newcastle upon Tyne Hospitals Trust, Freeman Hospital, High Heaton, Newcastle upon Tyne, UKAbstract: Gram-positive pathogens are a significant cause of morbidity and mortality in both community and health
Ager S, Gould K
doaj +5 more sources
Invasive Gram-Positive Bacterial Infection in Cancer Patients [PDF]
Systematic studies have shown that gram-positive organisms are the leading cause of invasive bacterial disease in patients with cancer. A broad range of gram-positive bacteria cause serious infections in the cancer patient with the greatest burden of disease being due to staphylococci, streptococci, and enterococci.
Thomas L Holland +2 more
openalex +3 more sources
Linezolid for resistant Gram-positive bacterial infections in children under 12 years: A meta-analysis [PDF]
Both linezolid and vancomycin have good efficacy in the treatment of resistant Gram-positive bacterial infections. This systematic review and meta-analysis aimed to compare the efficacy and safety of linezolid vs vancomycin for the treatment of resistant
Wu Qian +3 more
doaj +2 more sources
Teixobactin: A Novel Antibiotic in Treatment of Gram Positive Bacterial Infections [PDF]
Sir, Antimicrobial resistance have emerged as a serious concern worldwide. In spite of the best effort in developing novel antimicrobial agents employing advanced techniques like computer-aided drug design, proteomics, genomics, combinatorial synthesis and high- throughput screening, there is lack of newer antibiotics in the process of development ...
Arunava Kali
doaj +3 more sources
Serological detection of Gram-positive bacterial infection around prostheses [PDF]
Coagulase-negative staphylococci produce an exocellular glycolipid antigen which has potential as a serological marker of infection in bone. The value of this newly detected antigen was investigated by enzyme-linked immunosorbent assay (ELISA) in 15 patients with culture-proven infection of prostheses caused by Gram-positive bacteria.
Mohammed Rafiq +6 more
openalex +3 more sources
Development of Methionyl-tRNA Synthetase Inhibitors as Antibiotics for Gram-Positive Bacterial Infections [PDF]
ABSTRACT Antibiotic-resistant bacteria are widespread and pose a growing threat to human health. New antibiotics acting by novel mechanisms of action are needed to address this challenge. The bacterial methionyl-tRNA synthetase (MetRS) enzyme is essential for protein synthesis, and the type found in Gram-positive bacteria is ...
Omeed Faghih +11 more
openalex +3 more sources
Otitis Media (OM) is a common disease. It represents a serious problem mainly after winter outbreaks of respiratory tract infections (RTI); its consequences are hearing weakness; or even loss in adults and problems in speech in children.
Weam Saad Al-Hamadany
doaj +3 more sources
OBJECTIVES: Delay in the treatment of pleural infection may contribute to its high mortality. In this retrospective study, we aimed to evaluate the diagnostic accuracy of pleural adenosine deaminase in discrimination between Gram-negative and Gram ...
Ruolin Li +3 more
doaj +2 more sources
Gram positive bacterial infections in immunocompromised patients with HIV infection [PDF]
Results Incidence: group A vs. group B: BI-114 PIH (22.66%) vs. 1442 Px (8.7%) (p=0.000, RR=17.23), GPI-59 (51.75%) vs. 378 (26.21%) (p 0.05) erythromycin, 13 (41.93%) vs.
Andreea Cristina Stoian +7 more
openalex +2 more sources

