Results 1 to 10 of about 3,331 (249)

Phage therapy as a revolutionary medicine against Gram-positive bacterial infections [PDF]

open access: diamondBeni-Suef University Journal of Basic and Applied Sciences, 2021
Background Antibiotic resistance among pathogenic bacteria has created a global emergency, prompting the hunt for an alternative cure. Bacteriophages were discovered over a century ago and have proven to be a successful replacement during antibiotic ...
Archana Loganathan   +5 more
doaj   +5 more sources

Clinical update on linezolid in the treatment of Gram-positive bacterial infections

open access: goldInfection and Drug Resistance, 2012
Sally Ager, Kate GouldDepartment of Microbiology, Newcastle upon Tyne Hospitals Trust, Freeman Hospital, High Heaton, Newcastle upon Tyne, UKAbstract: Gram-positive pathogens are a significant cause of morbidity and mortality in both community and health
Ager S, Gould K
doaj   +5 more sources

Invasive Gram-Positive Bacterial Infection in Cancer Patients [PDF]

open access: greenClinical Infectious Diseases, 2014
Systematic studies have shown that gram-positive organisms are the leading cause of invasive bacterial disease in patients with cancer. A broad range of gram-positive bacteria cause serious infections in the cancer patient with the greatest burden of disease being due to staphylococci, streptococci, and enterococci.
Thomas L Holland   +2 more
openalex   +3 more sources

Linezolid for resistant Gram-positive bacterial infections in children under 12 years: A meta-analysis [PDF]

open access: goldOpen Medicine, 2022
Both linezolid and vancomycin have good efficacy in the treatment of resistant Gram-positive bacterial infections. This systematic review and meta-analysis aimed to compare the efficacy and safety of linezolid vs vancomycin for the treatment of resistant
Wu Qian   +3 more
doaj   +2 more sources

Teixobactin: A Novel Antibiotic in Treatment of Gram Positive Bacterial Infections [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2015
Sir, Antimicrobial resistance have emerged as a serious concern worldwide. In spite of the best effort in developing novel antimicrobial agents employing advanced techniques like computer-aided drug design, proteomics, genomics, combinatorial synthesis and high- throughput screening, there is lack of newer antibiotics in the process of development ...
Arunava Kali
doaj   +3 more sources

Serological detection of Gram-positive bacterial infection around prostheses [PDF]

open access: bronzeThe Journal of Bone and Joint Surgery. British volume, 2000
Coagulase-negative staphylococci produce an exocellular glycolipid antigen which has potential as a serological marker of infection in bone. The value of this newly detected antigen was investigated by enzyme-linked immunosorbent assay (ELISA) in 15 patients with culture-proven infection of prostheses caused by Gram-positive bacteria.
Mohammed Rafiq   +6 more
openalex   +3 more sources

Development of Methionyl-tRNA Synthetase Inhibitors as Antibiotics for Gram-Positive Bacterial Infections [PDF]

open access: bronzeAntimicrobial Agents and Chemotherapy, 2017
ABSTRACT Antibiotic-resistant bacteria are widespread and pose a growing threat to human health. New antibiotics acting by novel mechanisms of action are needed to address this challenge. The bacterial methionyl-tRNA synthetase (MetRS) enzyme is essential for protein synthesis, and the type found in Gram-positive bacteria is ...
Omeed Faghih   +11 more
openalex   +3 more sources

Isolation and Identification of Gram Positive Cocci Bacterial Pathogens from Sappurative Otitis Media Infections

open access: goldThe Iraqi Journal of Veterinary Medicine, 2013
Otitis Media (OM) is a common disease. It represents a serious problem mainly after winter outbreaks of respiratory tract infections (RTI); its consequences are hearing weakness; or even loss in adults and problems in speech in children.
Weam Saad Al-Hamadany
doaj   +3 more sources

Pleural effusion adenosine deaminase: a candidate biomarker to discriminate between Gram-negative and Gram-positive bacterial infections of the pleural space

open access: goldClinics, 2016
OBJECTIVES: Delay in the treatment of pleural infection may contribute to its high mortality. In this retrospective study, we aimed to evaluate the diagnostic accuracy of pleural adenosine deaminase in discrimination between Gram-negative and Gram ...
Ruolin Li   +3 more
doaj   +2 more sources

Gram positive bacterial infections in immunocompromised patients with HIV infection [PDF]

open access: goldBMC Infectious Diseases, 2013
Results Incidence: group A vs. group B: BI-114 PIH (22.66%) vs. 1442 Px (8.7%) (p=0.000, RR=17.23), GPI-59 (51.75%) vs. 378 (26.21%) (p 0.05) erythromycin, 13 (41.93%) vs.
Andreea Cristina Stoian   +7 more
openalex   +2 more sources

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