Phage therapy as a revolutionary medicine against Gram-positive bacterial infections [PDF]
Beni-Suef University Journal of Basic and Applied Sciences, 2021 Background Antibiotic resistance among pathogenic bacteria has created a global emergency, prompting the hunt for an alternative cure. Bacteriophages were discovered over a century ago and have proven to be a successful replacement during antibiotic ...
Archana Loganathan +5 more
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Teixobactin: A Novel Antibiotic in Treatment of Gram Positive Bacterial Infections [PDF]
Journal of Clinical and Diagnostic Research, 2015 Sir, Antimicrobial resistance have emerged as a serious concern worldwide. In spite of the best effort in developing novel antimicrobial agents employing advanced techniques like computer-aided drug design, proteomics, genomics, combinatorial synthesis and high- throughput screening, there is lack of newer antibiotics in the process of development ...
Arunava Kali
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Linezolid for resistant Gram-positive bacterial infections in children under 12 years: A meta-analysis [PDF]
Open Medicine, 2022 Both linezolid and vancomycin have good efficacy in the treatment of resistant Gram-positive bacterial infections. This systematic review and meta-analysis aimed to compare the efficacy and safety of linezolid vs vancomycin for the treatment of resistant
Wu Qian +3 more
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Sepsis patients with first and second-hit infections show different outcomes depending on the causative organism [PDF]
Frontiers in Microbiology, 2016 Objective. With improving rates of initial survival in severe sepsis, second-hit infections that occur following resolution of the primary insult carry an increasing burden of morbidity.
Matthew eMorgan +9 more
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Efficacy and Safety of Contezolid as Salvage Treatment for Gram-Positive Bacterial Infections: A Retrospective Multicenter Study [PDF]
Infection and Drug ResistanceShujuan Ji,1 Zhihui Zhou,1 Yan Chen,1 Lu Sun,1 Binfeng Yu,1 Yunsong Yu2 1Department of Infectious Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China; 2Department of Infectious Diseases ...
Ji S, Zhou Z, Chen Y, Sun L, Yu B, Yu Y
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Continuous versus intermittent vancomycin infusions in critically ill children with gram-positive bacterial infections: a randomized controlled trial [PDF]
BMC Infectious DiseasesObjective This randomized controlled trial (RCT) compares continuous intravenous infusion (CIV) and intermittent infusion of vancomycin (IIV) regimens (40 mg/kg/day) in PICU patients with Gram-positive infections.
Yahui Wu +9 more
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Pleural effusion adenosine deaminase: a candidate biomarker to discriminate between Gram-negative and Gram-positive bacterial infections of the pleural space [PDF]
Clinics, 2016 OBJECTIVES: Delay in the treatment of pleural infection may contribute to its high mortality. In this retrospective study, we aimed to evaluate the diagnostic accuracy of pleural adenosine deaminase in discrimination between Gram-negative and Gram ...
Ruolin Li +3 more
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Clinical update on linezolid in the treatment of Gram-positive bacterial infections
Infection and Drug Resistance, 2012 Sally Ager, Kate GouldDepartment of Microbiology, Newcastle upon Tyne Hospitals Trust, Freeman Hospital, High Heaton, Newcastle upon Tyne, UKAbstract: Gram-positive pathogens are a significant cause of morbidity and mortality in both community and health
Ager S, Gould K
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Treatment of erythrasma: A double-blinded randomized controlled trial on the clinical application of clotrimazole and sertaconazole [PDF]
Journal of Research in Clinical Medicine, 2020 Introduction: Topical clotrimazole and sertaconazole may be effective in the treatment of erythrasma, a superficial skin infection developed by a group of aerobic microorganisms. This study aimed to compare the effect of clotrimazole and sertaconazole on
Hamideh Herizchi Ghadim +3 more
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Characteristics and risk factors of secondary bacterial infections in COVID-19 patients
Antimicrobial Stewardship & Healthcare Epidemiology, 2023 Objective: To describe the characteristics and find out risk factors of COVID-19 patients infected with different categories of bacteria. Design: Case-control.
Guangjie Wu +3 more
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