Results 11 to 20 of about 272,903 (354)

Granule Leakage Induces Cell-Intrinsic, Granzyme B-Mediated Apoptosis in Mast Cells

open access: yesFrontiers in Cell and Developmental Biology, 2021
Mast cells are multifunctional immune cells scattered in tissues near blood vessels and mucosal surfaces where they mediate important reactions against parasites and contribute to the pathogenesis of allergic reactions.
Sabrina Sofia Burgener   +14 more
doaj   +1 more source

Mast cell granule motility and exocytosis is driven by dynamic microtubule formation and kinesin-1 motor function

open access: yesPLoS ONE, 2022
Mast cells are tissue-resident immune cells that have numerous cytoplasmic granules which contain preformed pro-inflammatory mediators. Upon antigen stimulation, sensitized mast cells undergo profound changes to their morphology and rapidly release ...
Jeremies Ibanga   +3 more
doaj   +2 more sources

The periglomerular cell of the olfactory bulb and its role in controlling mitral cell spiking: a computational model. [PDF]

open access: yesPLoS ONE, 2013
Interneurons in the olfactory bulb are key elements of odor processing but their roles have not yet being fully understood. Two types of inhibitory interneurons, periglomerular and granule cells, act at two different levels within the olfactory bulb and ...
Denise Arruda   +2 more
doaj   +1 more source

Origins, Development, and Compartmentation of the Granule Cells of the Cerebellum

open access: yesFrontiers in Neural Circuits, 2021
Granule cells (GCs) are the most numerous cell type in the cerebellum and indeed, in the brain: at least 99% of all cerebellar neurons are granule cells.
G. Giacomo Consalez   +3 more
doaj   +1 more source

Task-dependent optimal representations for cerebellar learning

open access: yeseLife, 2023
The cerebellar granule cell layer has inspired numerous theoretical models of neural representations that support learned behaviors, beginning with the work of Marr and Albus.
Marjorie Xie   +3 more
doaj   +1 more source

Short-Term Plasticity in Cortical GABAergic Synapses on Olfactory Bulb Granule Cells Is Modulated by Endocannabinoids

open access: yesFrontiers in Cellular Neuroscience, 2021
Olfactory bulb and higher processing areas are synaptically interconnected, providing rapid regulation of olfactory bulb circuit dynamics and sensory processing. Short-term plasticity changes at any of these synapses could modulate sensory processing and
Fu-Wen Zhou, Adam C. Puche
doaj   +1 more source

RNA Granules in Germ Cells [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2011
"Germ granules" are cytoplasmic, nonmembrane-bound organelles unique to germline. Germ granules share components with the P bodies and stress granules of somatic cells, but also contain proteins and RNAs uniquely required for germ cell development. In this review, we focus on recent advances in our understanding of germ granule assembly, dynamics, and ...
Ekaterina, Voronina   +3 more
openaire   +2 more sources

Hilar mossy cell circuitry controlling dentate granule cell excitability

open access: yesFrontiers in Neural Circuits, 2013
Glutamatergic hilar mossy cells of the dentate gyrus can either excite or inhibit distant granule cells, depending on whether their direct excitatory projections to granule cells or their projections to local inhibitory interneurons dominate. However, it
Seiichiro eJinde   +2 more
doaj   +1 more source

Drug-induced stress granule formation protects sensory hair cells in mouse cochlear explants during ototoxicity [PDF]

open access: yes, 2019
Stress granules regulate RNA translation during cellular stress, a mechanism that is generally presumed to be protective, since stress granule dysregulation caused by mutation or ageing is associated with neurodegenerative disease.
Dawson, Sally J.   +6 more
core   +2 more sources

Polyphosphate granule biogenesis is temporally and functionally tied to cell cycle exit during starvation in Pseudomonas aeruginosa [PDF]

open access: yes, 2017
Polyphosphate (polyP) granule biogenesis is an ancient and ubiquitous starvation response in bacteria. Although the ability to make polyP is important for survival during quiescence and resistance to diverse environmental stresses, granule genesis is ...
Dieterle, Michael G.   +5 more
core   +1 more source

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