Results 21 to 30 of about 272,903 (354)

Mitral cell spike synchrony modulated by dendrodendritic synapse location

Frontiers in Computational Neuroscience, 2012
On their long lateral dendrites, mitral cells of the olfactory bulb form dendrodendritic synapses with large populations of granule cell interneurons. The mitral-granule cell microcircuit operating through these reciprocal synapses has been implicated in
Thomas S McTavish, Michele eMigliore, Gordon M Shepherd, Michael L. Hines   +3 more
doaj   +1 more source

Hippocampal neurogenesis is not enhanced by lifelong reduction of glucocorticoid levels. [PDF]

, 2005
Neurogenesis of dentate gyrus granule cells is generally considered to be negatively regulated by glucocorticoids. We tested the hypothesis that exposure to low plasma corticosteroid levels starting in the early postnatal period enhances granule cell ...
Baram, Tallie Z, Bender, Roland A, Brunson, Kristen L   +2 more
core   +1 more source

Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus

Molecular Brain, 2010
New granule cells are continuously generated in the dentate gyrus of the adult hippocampus. During granule cell maturation, the mechanisms that differentiate new cells not only describe the degree of cell differentiation, but also crucially regulate the ...
Ohira, Koji, Hagihara, Hideo, Toyama, Keiko, Takao Keizo, Kanai Masaaki, Funakoshi Hiroshi, Nakamura Toshikazu, Miyakawa Tsuyoshi   +7 more
doaj   +1 more source

Acute ethanol exposure inhibits silencing of cerebellar Golgi cell firing induced by granule cell axon input

Frontiers in Integrative Neuroscience, 2014
Golgi cells (GoCs) are specialized interneurons that provide inhibitory input to granule cells in the cerebellar cortex. GoCs are pacemaker neurons that spontaneously fire action potentials, triggering spontaneous inhibitory postsynaptic currents in ...
Paolo eBotta, Aya eZucca, Carlos Fernando Valenzuela   +2 more
doaj   +1 more source

Biosensor measurement of purine release from cerebellar cultures and slices [PDF]

, 2010
We have previously described an action-potential and Ca2+-dependent form of adenosine release in the molecular layer of cerebellar slices. The most likely source of the adenosine is the parallel fibres, the axons of granule cells. Using microelectrode
Dale, Nicholas, Eason, Robert, Wall, Mark J.   +2 more
core   +3 more sources

Long-Term Effects of Moderate Concussive Brain Injury During Adolescence on Synaptic and Tonic GABA Currents in Dentate Granule Cells and Semilunar Granule Cells

Frontiers in Neuroscience, 2022
Progressive physiological changes in the hippocampal dentate gyrus circuits following traumatic brain injury (TBI) contribute to temporal evolution of neurological sequelae.
Akshay Gupta, Akshay Gupta, Laura Dovek, Archana Proddutur, Archana Proddutur, Fatima S. Elgammal, Vijayalakshmi Santhakumar, Vijayalakshmi Santhakumar   +7 more
doaj   +1 more source

Population-scale organization of cerebellar granule neuron signaling during a visuomotor behavior. [PDF]

, 2017
Granule cells at the input layer of the cerebellum comprise over half the neurons in the human brain and are thought to be critical for learning. However, little is known about granule neuron signaling at the population scale during behavior.
Aksay, Emre RF, Goldman, Mark S, Lee, Melanie M, Lim, Sukbin, Ramirez, Alexandro D, Sylvester, Sherika JG   +5 more
core   +2 more sources

Granule-Dependent NK Cell Killing of Cryptococcus Requires Kinesin to Reposition the Cytolytic Machinery for Directed Cytotoxicity

Cell Reports, 2018
Summary: Cryptococcus is the most important cause of fungal meningitis in immunocompromised individuals. Host defense against Cryptococcus involves direct killing by NK cells.
Henry Ogbomo, Martina Timm-McCann, Tavish Barnes, Richard F. Xiang, Khusraw Jamil, Anutosh Ganguly, Danuta Stack, Shaunna M. Huston, Shu Shun Li, Pina Colarusso, Christopher H. Mody   +10 more
doaj   +1 more source

Neurogenesis Drives Stimulus Decorrelation in a Model of the Olfactory Bulb [PDF]

, 2012
The reshaping and decorrelation of similar activity patterns by neuronal networks can enhance their discriminability, storage, and retrieval. How can such networks learn to decorrelate new complex patterns, as they arise in the olfactory system?
A Arevian, A Fantana, A Mouret, A Mouret, A Sahay, AM McNamara, B Johnson, B Winner, Boris S. Gutkin, C Linster, C Rochefort, CW Lin, D Chaudhury, D Rinberg, D Wilson, DA Wilson, DJ Heeger, E Yaksi, F David, F Kermen, F Lazarini, F Lazarini, GA Cecchi, GK Mak, GK Mak, GM Shepherd, Hermann Riecke, I Imayoshi, I Ortega-Perez, J Ninkovic, JT Davie, L Belnoue, L Petreanu, LM Kay, M Alonso, M Satou, M Valley, M Whitman, M Yamaguchi, MC Whitman, MD Döbrössy, MM Moreno, MT Wiechert, N Kaneko, N Mandairon, N Mandairon, N Mandairon, N Mandairon, N Mandairon, N Mandairon, N Miwa, O Escanilla, P Panzanelli, PA Brennan, PE Castillo, PM Lledo, Q Nai, R Pressler, RE Dolmetsch, RW Friedrich, RW Friedrich, S Sultan, S Sultan, S Sultan, S Wick, Siu-Fai Chow, SR Olsen, SS Magavi, Stuart D. Wick, SW Kuffler, SX Luo, T Shingo, TA Cleland, TA Cleland, TB Woolf, TK Yokoyama, V Breton-Provencher, V Egger, V Egger, W Kelsch, W Kim, Y Gao   +81 more
core   +6 more sources

Cadherin-2 controls directional chain migration of cerebellar granule neurons.

PLoS Biology, 2009
Long distance migration of differentiating granule cells from the cerebellar upper rhombic lip has been reported in many vertebrates. However, the knowledge about the subcellular dynamics and molecular mechanisms regulating directional neuronal migration
Sandra Rieger, Niklas Senghaas, Axel Walch, Reinhard W Köster   +3 more
doaj   +1 more source