A Scalable Model of Cerebellar Adaptive Timing and Sequencing: The Recurrent Slide and Latch (RSL) Model [PDF]
From the dawn of modern neural network theory, the mammalian cerebellum has been a favored object of mathematical modeling studies. Early studies focused on the fan-out, convergence, thresholding, and learned weighting of perceptual-motor signals within ...
Bullock, Daniel, Rhodes, Bradley
core +1 more source
Synaptophysin and synaptoporin expression in the developing rat olfactory system [PDF]
The expressions of two closely related synaptic vesicle antigens synaptophysin and synaptoporin were examined in the olfactory system of the adult rat and during pre- and postnatal development.
Bayer+50 more
core +1 more source
Mast cell clones: a model for the analysis of cellular maturation. [PDF]
Cloned mouse mast cells resemble, by ultrastructure, immature mast cells observed in vivo. These mast cell clones can be grown in the absence of any other cells, facilitating direct investigations of their biochemistry and function.
Cantor, H+10 more
core +2 more sources
Exploring adult hippocampal neurogenesis using optogenetics [PDF]
In the 1980s, it was widely accepted that new neurons are continuously generated in the dentate gyrus of the mammalian hippocampus. Since its acceptance, researchers have employed various techniques and behavioral paradigms to study the proliferation ...
Pinardo, Heinrich
core
The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress [PDF]
The MRE11/RAD50/NBS1 (MRN) complex is a major sensor of DNA double strand breaks, whose role in controlling faithful DNA replication and preventing replication stress is also emerging. Inactivation of the MRN complex invariably leads to developmental and/
A Dupre+70 more
core +1 more source
On the Existence of a Cell Granule in a Thermophilic Bacterium.
ConclusionThe red fraction, previously isolated from a stenothermophilic bacterium, represents a specific piece of bacterial protoplasm. The evidence presented consists of photographs taken with the phase contrast microscope, photomicrographs of stained preparations of bacteria and of red fraction, and of enzymatic data. The enzymatic data rest chiefly
James Heotis+3 more
openaire +3 more sources
Network structure determines patterns of network reorganization during adult neurogenesis [PDF]
New cells are generated throughout life and integrate into the hippocampus via the process of adult neurogenesis. Epileptogenic brain injury induces many structural changes in the hippocampus, including the death of interneurons and altered connectivity ...
Ben-Jacob, Eshel+4 more
core
Adaptive Neural Models of Queuing and Timing in Fluent Action [PDF]
Temporal structure in skilled, fluent action exists at several nested levels. At the largest scale considered here, short sequences of actions that are planned collectively in prefrontal cortex appear to be queued for performance by a cyclic competitive ...
Bullock, Daniel
core +1 more source
In vivo characterization of hippocampal electrophysiological processes in the heterozygous Pten knockout model of autism [PDF]
While cognitive deficits have been described in the heterozygous Pten (+/-) KO mouse model of autism, little work has been done to demonstrate how corresponding in vitro physiological alterations in this model may underpin these cognitive deficits in ...
Barry, Jeremy+2 more
core +1 more source
Histone bivalency regulates the timing of cerebellar granule cell development. [PDF]
Mätlik K+4 more
europepmc +1 more source