Heparan sulfate mimetics can efficiently mobilize long-term hematopoietic stem cells
Background Although mobilization of hematopoietic stem cells and hematopoietic progenitor cells can be achieved with a combination of granulocyte colony-stimulating factor and plerixafor (AMD3100), improving approaches for hematopoietic progenitor cell ...
Fabio Di Giacomo +6 more
doaj +1 more source
Aim. To evaluate the changes in the total cellularity (Nuc) of the rat sciatic nerve regenerative neuroma (RegN) and its representation of CD90, CD44, CD146, and CD133 positive cells, as well as its neurotization under the conditions of dexamethasone ...
O. M. Grabovyi +4 more
doaj +1 more source
Effect in supralethally irradiated rats of granulocyte colony- stimulating factor and lisofylline on hematopoietic reconstitution by syngeneic bone marrow or whole organ passenger leukocytes [PDF]
We have previously shown the existence of migratory hematopoietic stem cells in adult solid organs. This study demonstrates that granulocyte colony- stimulating factor (G-CSF) and lisofylline, a phosphatidic acid inhibitor that suppresses hematopoiesis ...
Abdul Rao +23 more
core +1 more source
G-CSF Prevents the Progression of Structural Disintegration of White Matter Tracts in Amyotrophic Lateral Sclerosis: A Pilot Trial [PDF]
Background: The hematopoietic protein Granulocyte-colony stimulating factor (G-CSF) has neuroprotective and regenerative properties. The G-CSF receptor is expressed by motoneurons, and G-CSF protects cultured motoneuronal cells from apoptosis.
A Nitkunan +64 more
core +6 more sources
Effect of filgrastim (Recombinant human granulocyte colony stimulating factor) on spatial memory in aged rats [PDF]
Background: Apart from functioning as a multimodal hematopoietic growth factor, granulocyte colony-stimulating factor (G-CSF) causes intense consequences on the brain.
Mehrazin, E., Sepehri, H.
core +1 more source
Lack of effect of the human GM-CSF analog E21R on the survival of primary human acute myeloid leukemia cells [PDF]
The granulocyte-macrophage colony-stimulating factor (GM-CSF) analog E21R binds to the GM-CSF receptor complex with low affinity and acts as a competitive antagonist.
Grandage, V.L. +3 more
core +1 more source
Towards a new understanding of decision-making by hematopoietic stem cells [PDF]
Cells within the hematopoietic stem cell compartment selectively express receptors for cytokines that have a lineage(s) specific role; they include erythropoietin, macrophage colony-stimulating factor, granulocyte colony-stimulating factor, granulocyte ...
Brown, Geoff
core +1 more source
Background Information about the long-term follow-up and safety of granulocyte colony-stimulating factor administration to healthy donors is limited.
Javier de la Rubia +9 more
doaj +1 more source
The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor [PDF]
Mobilized blood has supplanted bone marrow (BM) as the primary source of hematopoietic stem cells for autologous and allogeneic stem cell transplantation.
A Dar +47 more
core +1 more source
We present a seven-month-old boy referred to our hospital with a history of recurrent suppurative infections starting in his neonatal period. Anemia, absolute neutropenia absolute neutrophil count (ANC: 500 cells/pl), pneumonia, purulent otitis media ...
Volkan Hazar +3 more
doaj +1 more source

