Results 11 to 20 of about 40,561 (247)

Health-related quality of life in adult-type ovarian granulosa cell tumor survivors. [PDF]

Acta Obstet Gynecol Scand
The health‐related quality of life of adult‐type granulosa cell tumor survivors was similar to the general female population. Slight impairment was detected in areas of excretion and sexual activity. A history of tumor recurrence, an increasing number of other chronic illnesses, and financial difficulties each diminished health‐related quality of life.
Haltia UM, Torvinen S, Bryk S, Sintonen H, Tapper J.   +4 more
europepmc   +2 more sources

Oocyte-granulosa cell interactions [PDF]

Human Reproduction Update, 2000
In the past, different protocols of ovulation induction, aimed to overcome problems of anovulatory infertility in humans, have been developed during IVF programmes. However, administration of exogenous hormones may cause severe health problems, e.g. ovarian hyperstimulation syndrome.
openaire   +2 more sources

PMS2 gene mutation results in DNA mismatch repair system failure in a case of adult granulosa cell tumor

Journal of Ovarian Research, 2017
Background Granulosa cell tumors are rare ovarian malignancies. Their characteristics include unpredictable indolent growth with malignant potential and late recurrence. Approximately 95% are of adult type. Recent molecular studies have characterized the
Wen-Chung Wang, Ya-Ting Lee, Yen-Chein Lai   +2 more
doaj   +1 more source

Extraovarian granulosa cell tumor

Indian Journal of Pathology and Microbiology, 2009
Extraovarian granulosa cell tumor (GCT) is a very uncommon tumor, assumed to arise from the ectopic gonadal tissue along the embryonal route of the genital ridge. One such rare case of extraovarian GCT was encountered in a 58-year-old female who presented with a large intraabdominal lump.
Jayati Chakraborty, Sudipta Chakrabarti, Bitan Chattopadhyay, Prabir Chandra Paul   +3 more
openaire   +4 more sources

Paracrine effects of oocyte secreted factors and stem cell factor on porcine granulosa and theca cells in vitro

Reproductive Biology and Endocrinology, 2003
Oocyte control of granulosa and theca cell function may be mediated by several growth factors via a local feedback loop(s) between these cell types. This study examined both the role of oocyte-secreted factors on granulosa and thecal cells, cultured ...
Webb Bob, Mitchell Marcus RP, Brankin Victoria, Hunter Morag G   +3 more
doaj   +1 more source

Granulosa cell proliferation is inhibited by PGE2 in the primate ovulatory follicle

Animal Cells and Systems, 2020
Prostaglandin E2 (PGE2) is a key paracrine mediator of ovulation. Few specific PGE2-regulated gene products have been identified, so we hypothesized that PGE2 may regulate the expression and/or activity of a network of proteins to promote ovulation.
Patric S. Lundberg, Gil J. Moskowitz, Carmel Bellacose, Esra Demirel, Heidi A. Trau, Diane M. Duffy   +5 more
doaj   +1 more source

FGF12 regulates cell cycle gene expression and promotes follicular granulosa cell proliferation through ERK phosphorylation in geese

Poultry Science, 2023
: The granulosa cells play an important role in the fate of follicular development or atresia in poultry. Fibroblast growth factor 12 (FGF12) is downregulated in atretic follicles and may be involved in regulating granulosa cell survival in previous ...
Wanli Yang, Shiqi Yu, Jinzhou Peng, Penghui Chang, Xingyong Chen   +4 more
doaj  

Recurrent granulosa cell tumor of the retroperitoneum during the COVID-19 Pandemic

Gynecologic Oncology Reports, 2022
Extraovarian granulosa cell tumors are rare with very few cases of isolated retroperitoneal granulosa cell tumors reported in the literature. Granulosa cell tumors are notorious for late recurrences and patients should have long term oncologic follow up.
Yasmin Abedin, Upasana Madan, Deena Graham, Mira C. Hellmann   +3 more
doaj  

Transcriptomic analysis of the effects exerted by curcumin on dihydrotestosterone-induced ovarian granulosa cells

Frontiers in Endocrinology
PurposeHyperandrogenism is a leading cause of developmental retardation in ovarian granulosa cells. Previous studies have indicated that curcumin significantly improves follicular dysplasia, a characteristic of the polycystic ovary syndrome.
Dejian Chen, Dejian Chen, Qian Yu, Shuhao Sheng, Lingshi Cai, Jisuo Zheng, Yaling Zhang   +6 more
doaj   +1 more source

Dynamic expression patterns of Irx3 and Irx5 during germline nest breakdown and primordial follicle formation promote follicle survival in mouse ovaries.

PLoS Genetics, 2018
Women and other mammalian females are born with a finite supply of oocytes that determine their reproductive lifespan. During fetal development, individual oocytes are enclosed by a protective layer of granulosa cells to form primordial follicles that ...
Anqi Fu, Sydney M Oberholtzer, Stefan Bagheri-Fam, Raphael H Rastetter, Claire Holdreith, Valeria L Caceres, Steven V John, Sarah A Shaw, Kathleen J Krentz, Xiaoyun Zhang, Chi-Chung Hui, Dagmar Wilhelm, Joan S Jorgensen   +12 more
doaj   +1 more source