Results 131 to 140 of about 53,350 (260)

PTPN1/PTPN2 inhibition improves NK cancer therapy by enhancing IL-2 and mitigating TGFβ1 responses. [PDF]

EMBO Rep
Feng CH, Peltier L, Chouleur T, DiPonzio M, Aubry I, Poirier AJ, Cordova ZM, Shen Y, Tabariès S, Cao X, Chen G, Bikfalvi A, Vidal SM, Siegel PM, Laneuville P, Tremblay ML.   +15 more
europepmc   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Editorial: Roles of granzymes in inflammation, aging, and autoimmunity

Frontiers in Immunology
Fehim Esen, Christopher T. Turner
doaj   +1 more source

STAT6 inhibition of M2 macrophages suppresses tumor growth by modulating the tumor microenvironment in colon cancer model. [PDF]

Front Immunol
Yeun G, Han IH, Choi I, Kim S, Choi H, Bae H.   +5 more
europepmc   +1 more source

Tumor‐Regional Immune Microenvironment: A Critical Factor in the Design of Radiotherapy–Immunotherapy Combination Trials

International Journal of Cancer, EarlyView.
ABSTRACT Clinical trials combining radiotherapy (RT) with immune checkpoint blockade (ICB) have shown improved outcomes in only a fraction of patients, and optimal strategies for integrating these modalities remain under intense investigation. With a few exceptions, phase III combination trials have yielded disappointing results.
Xuanwei Zhang, Hui Wang, Weiyan Tang, Kai Kang, Kateryna Onyshchenko, Taotao Huang, Dan Liu, Jianxin Xue, You Lu, Gabriele Niedermann, Ren Luo   +10 more
wiley   +1 more source

CD73 activity controls cytotoxic CD4 T-cell response driving myocardial pathology in chronic Chagas disease. [PDF]

Front Immunol
Bergero G, Mazzocco YL, Cejas Gallardo ZM, Rivarola W, Del Rosso S, Aoki MP.   +5 more
europepmc   +1 more source

Anti‐NMDA receptor autoimmune encephalitis associated with ovarian teratoma: A case series and literature review

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 23-30, April 2025.
Abstract Autoimmune encephalitis is a group of disorders characterized by symptoms of dysfunction of the limbic and extra‐limbic systems that occur in association with antibodies against intracellular antigens, synapses, or proteins located on the surface of nerve cells. Anti‐NMDA (N‐methyl‐D‐aspartate) receptor encephalitis was first described in 2007
Pham Ba Nha, Nguyen Phuong Tu, Nguyen Viet Ha, Duong Thi Thu Hien, Nguyen Thi Thu Phuong, Nguyen Anh Son, Nguyen Tien Hoang   +6 more
wiley   +1 more source

Indolent natural killer-cell lymphoproliferative disorder of the gallbladder: a rare case report. [PDF]

Front Oncol
Jiang Y, Xie X, Gao Z, Xu W, Wang Y.
europepmc   +1 more source

Bile acid metabolism and signaling in human and animal health: A One Health perspective

iMetaOmics, EarlyView.
Bile acids maintain host homeostasis through enterohepatic circulation, microbial transformation, and bile acid receptor signaling, thereby regulating glucose and lipid metabolism, intestinal barrier integrity, and immunity. These effects support human disease intervention and health‐oriented animal production, reducing drug dependence and residue ...
Lei Li, Shuai Liu, Zhijun Cao, Yangchun Cao, Shengru Wu, Lu Deng, Junhu Yao, Jun Zhang   +7 more
wiley   +1 more source

KLRG1 defines a distinct tumor-infiltrating granzyme K+ CD8 + T cell population. [PDF]

J Cancer Res Clin Oncol
Thomas J, Kennedy S, Darcy S, Malaco H, Chambwe N, Kamdar D, Periera L, Salama A, Scarola D, Miles B, Frank D, Seetharamu N, Mandal R.   +12 more
europepmc   +1 more source