The gene and virus-induced expression of IRF-5 in grass carp Ctenopharyngodon idella [PDF]
The interferon regulatory factor 5 (IRF-5) is known to be involved in the innate immune response and in the regulation of DNA damage-induced apoptosis.
Xu, Qiao Q. +5 more
core
Toll-like receptor 4 signaling pathway can be triggered by grass carp reovirus and Aeromonas hydrophila infection in rare minnow Gobiocypris rarus [PDF]
Toll-like receptor 4 (TLR4) is critical for LPS recognition and cellular responses. It also recognizes some viral envelope proteins. Detection mostly results in the inflammation rather than specific antiviral responses. However, it's unclear in fish.
Yang, Chunrong +5 more
core +1 more source
Prokaryotic expression and immunoassay of grass carp reovirus capsid VP6 protein
Grass carp reovirus (GCRV) of the genus Aquareovirus and the family Reoviridae causes a severe hemorrhagic disease in grass carp fingerlings in China. GCRV genome is composed of 11 double-stranded RNA segments, of which segment 8 encodes the major core capsid protein VP6.
Y, Zhou, Y D, Fan, L B, Zeng, J, Ma
openaire +2 more sources
Enhanced grass carp reovirus resistance of Mx-transgenic rare minnow (Gobiocypris rarus) [PDF]
In the interferon-induced antiviral mechanisms, the Mx pathway is one of the most powerful. Mx proteins have direct antiviral activity and inhibit a wide range of viruses by blocking an early stage of the viral genome replication cycle.
Yang, Chunrong +6 more
core +1 more source
Genome segment S8 of grass carp hemorrhage virus encodes a virion protein [PDF]
The complete nucleotide sequence of the genome segment S8 of grass carp hemorrhage virus (GCHV) was determined from cDNA corresponding to the viral genomic RNA. It is 1,287 nucleotides in length and contains a large open reading frame that could encode a
Zhu, ZY +4 more
core
Immunization with recombinant baculovirus expressing the VP6 protein of grass carp reovirus induces immunity in grass carp [PDF]
Qin, Li +10 more
openaire +2 more sources
Nuclear factors of activated T cells (NFATs) are pivotal regulatory factors of immune responses, primarily by modulating T cell activity and regulating inflammatory cytokine gene transcription.
Yao Shen +8 more
doaj +1 more source
Grass carp reovirus type II (GCRV-II) has inflicted substantial economic damage to aquaculture industry due to highly contagious. To combat epidemic GCRV-II, we rational designed and constructed a multi-epitope nanoparticle vaccine (Pep-Fn) that ...
Fei-Fan Xu +4 more
doaj +1 more source
Nonstructural protein NS17 of grass carp reovirus Honghu strain promotes virus infection by mediating cell-cell fusion and apoptosis. [PDF]
Dai Y +9 more
europepmc +1 more source
Molecular Characterization of Outer Capsid Proteins VP5 and VP7 of Grass Carp Reovirus. [PDF]
Zhang F, Sun D, Fang Q.
europepmc +1 more source

