Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg +18 more
wiley +1 more source
Prevention in stroke - Current state, present gaps and probable next steps. [PDF]
Thielscher CS +5 more
europepmc +1 more source
Lessons From Drug Discovery for Cryoprotective Agent Design: An AI‐Oriented Perspective
Cryoprotectant design is reframed through the lens of drug discovery as a multiparameter optimization problem. This perspective highlights how AI and systematic design strategies could enable safer, more effective cryoprotectants, while identifying key limitations that currently constrain predictive progress in cryobiology. ABSTRACT Cryopreservation is
Dominika Wilczok +4 more
wiley +1 more source
Seaweed bioactives: A comprehensive review of their nutritional, medicinal, and functional roles. [PDF]
Elango AC +2 more
europepmc +1 more source
Femtosecond‐Laser‐Induced Physical Unclonable Random Maze Structure for Storage‐Free Encryption
Femtosecond‐laser‐induced gold random maze structures serve as multimodal physical unclonable functions for storage‐free encryption. Their stochastic optical, electrical, and Raman responses are generated by plasmon‐assisted Marangoni formation and converted into AES‐compatible keys without permanent secret‐key storage, offering a portable route toward
Shiru Jiang +6 more
wiley +1 more source
Why Do Consumers Hesitate to Purchase Near-Expiration Food? A Benefit-Risk Perspective on the Green Purchase Paradox. [PDF]
Chen X, Wang Y, Chen J, Yang C.
europepmc +1 more source
A machine learning‐assisted framework optimizes the KCl‐CaCl2‐LiCl ternary electrolyte. The optimized 13:35:52 mol% composition enables Ca‐based liquid metal batteries to operate stably at 480 °C, with >99.5% coulombic efficiency, ultralow self‐discharge, and excellent cycling stability, advancing low‐temperature large‐scale energy storage.
Xinglin Zhou +3 more
wiley +1 more source
Which population-level interventions promote physical activity equitably across socioeconomic groups? A rapid systematic review. [PDF]
Spiers GF +8 more
europepmc +1 more source
Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation
Exploring biodegradable Zn‐based implants offers a promising pathway to next‐generation biomedical devices with balanced degradation and biocompatibility. A comprehensive overview of biodegradable Zn‐based implants, covering their biological significance, material design principles, and advanced engineering strategies is provided.
Panfeng Zhao +10 more
wiley +1 more source
Content Analysis of Derived Intoxicating Cannabis Vape Product Attributes and Marketing In an Online Retail Environment. [PDF]
Chen-Sankey J +9 more
europepmc +1 more source

