Results 151 to 160 of about 2,664,104 (296)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Corporate social responsibility and behavioral intentions in an emerging market: The mediating roles of green brand image and green trust

Cleaner and Responsible Consumption
Bang Nguyen-Viet, Cong-Thanh Tran, Hoa T. B. Ngo   +2 more
semanticscholar   +1 more source

Building Trust in Sustainable Journeys: The Interplay Between Green Marketing, Green Brand Trust, and Tourism Purchase Intentions

Sustainability
This study aimed to examine the impact of green marketing on green purchase intention among tourists, with a specific focus on the mediating roles of brand engagement and green brand trust. The research sought to develop an explanatory model that integrates both cognitive and emotional dimensions in shaping sustainable tourism behavior.
openaire   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Greenwashing and Green Marketing on Social Media: Implications for Trust-Related Reactions in the Food Sector. [PDF]

Foods
Vukasović T, Trglavčnik M, Faganel A.
europepmc   +1 more source

Trust Formation in Green Marketing : The impact of shared environmental values, green communication and greenwashing on consumer trust

Background: Growing environmental awareness has increased the importance of green marketing, while simultaneously creating challenges for consumers in evaluating the credibility of brands’ environmental claims. As a result, consumer trust has become a central mechanism in reducing uncertainty within green marketing contexts.
Lindstedt, Christina, Wilbaste, Matilda
openaire   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Building trust, reducing skepticism: Green branding and sustainable purchase behavior in Indonesia

Asian Management and Business Review
Growing consumer pressure for businesses to adopt sustainable practices has made green branding a global priority, particularly in emerging markets such as Indonesia where environmental challenges and rising awareness intersect.
Sitti Mujahida Baharuddin, Badaruddin Badaruddin, Fatmasari Fatmasari, Hafipah Hafipah   +3 more
doaj  

Influential factors of residents' online green behavior in China: the mediating role of social trust. [PDF]

Sci Rep
Li Y, Yu X, Wang R.
europepmc   +1 more source