Results 131 to 140 of about 9,380 (213)

Beef-Derived Peptides Mediated Desensitization of Bitter Taste Receptor T2R14 Through GPCR Kinase 2. [PDF]

Nutrients
Singh N, Drube J, Hoffmann C, Aluko RE, Chelikani P.   +4 more
europepmc   +1 more source

Trastuzumab resistance features GRK2 activation.

We studied whole tumor gene expression in humans with pathologic complete response (pCR) or residual disease (RD) following treatment for HER2+ breast cancer to discover gene expression changes associated with, resulting from or causing resistance to treatment with the HER2-targeted treatment trastuzumab (Herceptin). We identified activation of GRK2 in
openaire   +2 more sources

Proteogenomic decoding of chemotherapy resistance in patients with triple-negative breast cancer. [PDF]

Genome Biol
Lee DK, Kim MH, Hwang Y, Kim SG, Ryu WJ, Kim GU, Yun HM, Park S, Lee JD, Han HJ, Kim GM, Kim KH, Park JB, Kim MJ, Koo JS, Kim JY, Park HS, Kim SI, Gee HY, Park S, Sohn J.   +20 more
europepmc   +1 more source

G protein-coupled receptor kinase 2 activity impairs cardiac glucose uptake and promotes insulin resistance after myocardial ischemia. [PDF]

, 2011
Chen M, Chuprun JK, Ciccarelli M, Dorn GW 2nd, Gao E, Gold JI, Gumpert A, Iaccarino G, Koch WJ, Otis NJ, Peroutka RJ, RENGO, GIUSEPPE, TRIMARCO, BRUNO, Wei Z   +13 more
core   +1 more source

Hepatic-vascular crosstalk via GRK2: fenofibrate improves endothelial function by restoring lipid metabolism and NO signaling in obese mice. [PDF]

Front Physiol
Taguchi K, Yonaiyama H, Furukawa T, Matsumoto T, Kobayashi T.   +4 more
europepmc   +1 more source

Quantifying effects of neutrophil memory on migration patterns using microfluidic platforms and ODE modeling of the mechanistic molecular pathways [PDF]

, 2018
Boribong, Brittany P, Ciupe, Stanca, Jonea, Caroline N, Kadelka, Mirjam Sarah, Lenzi, Mark J, Li, Liwu   +5 more
core   +1 more source

Small Extracellular Vesicle External Surface Adiponectin-Mediated Adipocytes/Cardiomyocytes Communication in Diabetic Ischemic Heart Failure. [PDF]

Circulation
Zhang Z, Zhu D, Liu C, Gan L, Zhao J, Meng Z, Yao P, Liu D, Gu G, Lopez B, Christopher TA, Wang Y, Ma X.   +12 more
europepmc   +1 more source

Adrenergic Receptors [PDF]

, 2016
D. Sorriento, E. Coscioni, G. Iaccarino, G. Santulli, M. Ciccarelli   +4 more
core   +1 more source

Cell-based and isoform-selective G protein-coupled receptor kinase assays for comprehensive inhibitor evaluation. [PDF]

Commun Biol
Blum NK, Kiefer MC, Decker A, Klement L, Matthees ESF, Weitzel V, Nagel F, Joseph B, Drube J, Uehling D, Hoffmann C, Schulz S.   +11 more
europepmc   +1 more source

Nicotine Diminishes Alpha2-Adrenergic Receptor-Dependent Protection Against Oxidative Stress in H9c2 Cardiomyocytes

Drug Design, Development and Therapy
Giselle Del Calvo, Celina M Pollard, Teresa Baggio Lopez, Jordana I Borges, Malka S Suster, Anastasios Lymperopoulos Laboratory for the Study of Neurohormonal Control of the Circulation, Department of Pharmaceutical Sciences (Pharmacology), Barry and ...
Del Calvo G, Pollard CM, Baggio Lopez T, Borges JI, Suster MS, Lymperopoulos A   +5 more
doaj