Results 111 to 120 of about 22,140 (207)

Development of a Core Outcome Set and Minimum Reporting Set for intervention studies in growth restriction in the NEwbOrN (COSNEON): study protocol for a Delphi study

Trials, 2019
Background Growth restriction in the newborn (GRN) can predispose to severe complications including hypoglycemia, sepsis, and necrotizing enterocolitis.
Martine Knol, Helena Wang, Frank Bloomfield, Tabitha Piet, Stefanie Damhuis, Asma Khalil, Wessel Ganzevoort, Sanne Gordijn   +7 more
doaj   +1 more source

Drought and salinity stress remodel Asian rice (Oryza sativa) leaf development through cell‐type‐specific regulatory programs

New Phytologist, EarlyView.
Osmotic stressors induce developmental and physiological changes in rice (Oryza sativa) seedlings, which are modulated by cell‐type‐specific gene expression and regulatory networks. We exposed plants to two levels of drought and salinity stress and measured the effects of these stressors on developing leaves by measuring physiological traits, ion ...
Sean M. Robertson, Obaid Maqsood, Chi Dang, Asher Pasha, Claudio Stasolla, Nicholas J. Provart, Olivia Wilkins   +6 more
wiley   +1 more source

Modifiers of GRN-associated frontotemporal lobar degeneration [PDF]

, 2017
: Heterozygous loss-of-function (LOF) mutations in the human progranulin gene (GRN) cause frontotemporal lobar degeneration (FTLD) by a mechanism of haploinsufficiency.
van der Zee, Julie, Van Mossevelde, Sara, Wauters, Eline, Cruts, Marc, Van Broeckhoven, Christine   +4 more
core  

From knowledge graph to topological data analysis: a novel framework to analyze gene regulatory networks for tomato–multi‐pathogen interactions

New Phytologist, EarlyView.
GENIAL framework. Summary of the main steps of the framework to infer and analyze GRN. Summary Tomato (Solanum lycopersicum), despite being the most important vegetable crop world‐wide, remains vulnerable to over 200 diseases caused by different pests.
Maxime Multari, Mathieu Carrière, Xavier Amorós‐Gabarrón, Krishna Kumar, Pratila Debnath, Alexina Damy, Ludo Andrianirina Mamisoa, Sebastian Lobentanzer, Julio Saez‐Rodriguez, Stéphanie Jaubert, Aurélien Dugourd, Justyna J. Olas, Silvia Bottini   +12 more
wiley   +1 more source

Neuron-microglia crosstalk in FTLD-GRN models [PDF]

Frontotemporal dementia (FTD) is a devastating neurodegenerative disease affecting more than a million people worldwide. Progranulin (PGRN) haploinsufficiency is the primary genetic cause of a subtype of frontotemporal lobar degeneration (FTLD-GRN ...
Reich, Marvin
core  

Spatial Regulation of Silicon Accumulation in Peduncle Confers Sheathed Spike in Barley

Plant Biotechnology Journal, EarlyView.
ABSTRACT Peduncle, the uppermost internode in cereals, connects the stem to the inflorescence and is critical for the transport of water, nutrients and photosynthetic assimilates. While peduncle length associates with plant height and its elongation is primarily regulated by phytohormones, we report a previously unrecognized mechanism involving the ...
Wenxue Wu, Congcong Jiang, Guangqi Gao, Namiki Mitani‐Ueno, Yu Guo, Jinhong Kan, Yehui Xiong, Martin Mascher, Zhongfu Ni, Jian Feng Ma, Ke Wang, Ping Yang   +11 more
wiley   +1 more source

Microglia in frontotemporal lobar degeneration with progranulin or C9ORF72 mutations

Annals of Clinical and Translational Neurology, 2019
Objective To identify clinicopathological differences between frontotemporal lobar degeneration (FTLD) due to mutations in progranulin (FTLD‐GRN) and chromosome 9 open reading frame 72 (FTLD‐C9ORF72).
Nobutaka Sakae, Shanu F. Roemer, Kevin F. Bieniek, Melissa E. Murray, Matthew C. Baker, Koji Kasanuki, Neill R. Graff‐Radford, Leonard Petrucelli, Marka Van Blitterswijk, Rosa Rademakers, Dennis W. Dickson   +10 more
doaj   +1 more source

Drought affects Fe deficiency‐induced responses in a purple durum wheat (Triticum turgidum subsp. durum) genotype

Plant Biology, EarlyView.
Combined Fe deficiency and drought in durum wheat trigger interactive responses: drought suppressed root Fe uptake regardless of Fe availability, and both stresses altered phytosiderophore release, ABA level and Fe transporter gene expression, revealing a trade‐off between water and Fe. Abstract Iron (Fe) is essential for plants and humans, with over 2
G. Quagliata, M. D. G. Molina, G. Mannino, E. Coppa, M. N. Saidi, S. Palombieri, F. Sestili, G. Vigani, S. Astolfi   +8 more
wiley   +1 more source

Sulphur‐mediated iron homeostasis in four tetraploid wheats (Triticum turgidum L.)

Plant Biology, EarlyView.
Polish wheat's tolerance to S limitation enables a well‐orchestrated response for efficient Fe acquisition when S is scarce, involving increased Fe accumulation, enhanced phytosiderophore release, and upregulated TdIRO2 and TdYSL15 expression. Abstract Sulphur (S) deficiency is known to hinder iron (Fe) uptake and distribution in wheat, mainly by ...
E. Coppa, G. Quagliata, M. D. G. Molina, M. Maghrebi, G. Vigani, F. Sestili, S. Astolfi   +6 more
wiley   +1 more source

Time‐series multi‐omics analysis of micronutrient stress in Sorghum bicolor reveals iron and zinc crosstalk and regulatory network conservation

Plant Biology, EarlyView.
Overlap between Fe and Zn responsive gene regulatory networks (GRNs) were found, indicative of micronutrient crosstalk, and conservation of root and leaf GRNs and genes suggests strong constraint on homeostasis networks in plants. Abstract Micronutrient stress impacts growth, biomass production, and grain yield in crops.
A. Mishra, A. Bhat, S. Kumari, R. Sharma, J. Braynen, D. Tadesse, S. El Alaoui, S. Seaver, N. Grosjean, D. Ware, M. Xie, T. Paape   +11 more
wiley   +1 more source