Results 51 to 60 of about 372,166 (319)

Parallels between the Developing Vascular and Neural Systems: Signaling Pathways and Future Perspectives for Regenerative Medicine

open access: yesAdvanced Science, 2021
Neurovascular disorders, which involve the vascular and nervous systems, are common. Research on such disorders usually focuses on either vascular or nervous components, without looking at how they interact.
Idoia Elorza Ridaura   +2 more
doaj   +1 more source

Learning the Biochemical Basis of Axonal Guidance: Using Caenorhabditis elegans as a Model

open access: yesBiomedicines, 2023
Aim: Experimental models are a powerful aid in visualizing molecular phenomena. This work reports how the worm Caenorhabditis elegans (C. elegans) can be effectively explored for students to learn how molecular cues dramatically condition axonal guidance
Andreia Teixeira-Castro   +7 more
doaj   +1 more source

The Computational Complexity of Duality

open access: yes, 2016
We show that for any given norm ball or proper cone, weak membership in its dual ball or dual cone is polynomial-time reducible to weak membership in the given ball or cone.
Friedland, Shmuel, Lim, Lek-Heng
core   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

BDNF/trkB Induction of Calcium Transients through Cav2.2 Calcium Channels in Motoneurons Corresponds to F-actin Assembly and Growth Cone Formation on β2-Chain Laminin (221)

open access: yesFrontiers in Molecular Neuroscience, 2017
Spontaneous Ca2+ transients and actin dynamics in primary motoneurons correspond to cellular differentiation such as axon elongation and growth cone formation.
Benjamin Dombert   +6 more
doaj   +1 more source

A conic manifold perspective of elliptic operators on graphs

open access: yes, 2007
We give a simple, explicit, sufficient condition for the existence of a sector of minimal growth for second order regular singular differential operators on graphs. We specifically consider operators with a singular potential of Coulomb type and base our
Birkhoff   +14 more
core   +1 more source

Influence of umbrella pine (Pinus pinea L.) stand type and tree characteristics on cone production [PDF]

open access: yes, 2016
Most umbrella pine (Pinus pinea L.) stands are managed as agroforestry systems, whose main production is fruit, due to the edible and highly nutritious kernels, and are frequently associated to natural or seeded pastures and grazing.
Afonso, Anabela   +3 more
core   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

The Neuron Navigators: Structure, function, and evolutionary history

open access: yesFrontiers in Molecular Neuroscience, 2023
Neuron navigators (Navigators) are cytoskeletal-associated proteins important for neuron migration, neurite growth, and axon guidance, but they also function more widely in other tissues.
Regina M. Powers   +5 more
doaj   +1 more source

The edge visualization metric: Quantifying the improvement of lung SBRT target definition with 4D CBCT

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Four‐dimensional cone‐beam CT (4D CBCT) incorporates oversampling of 3D data to reconstruct multi‐phase CBCT data sets representing distinct phases of the breathing cycle based on a diaphragmatic correlate of respiratory motion. Motion artifacts and blurring can be reduced relative to three‐dimensional cone‐beam (3D CBCT), allowing ...
Colton Baley   +4 more
wiley   +1 more source

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