Results 51 to 60 of about 33,389 (300)
Loss of chdp-1 causes reduced actin assembly in the dendritic growth cones.
, 2022 (A) A schematic diagram illustrating how the endogenously expressed CHDP-1 protein is specifically lighten up by GFP using the native and tissue-specific fluorescence approach.
Ting Zhao (434093) +5 more
core +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Wnt3a increases actin dynamics in growth cones.
, 2015 (A) DRG neurons were treated different concentrations of with CytoD and then recovered in control or Wnt3a growth media. Scale bar: 10μm. (B) Quantification shows that F-actin levels are after recovery are significantly higher in the presence of Wnt3a ...
Eleanna Stamatakou (781280) +2 more
core +1 more source
Arthritis Care &Research, Accepted Article.Objective To evaluate utility of an artificial intelligence (AI) health coach for systemic sclerosis (SSc) self‐management and identify patterns associated with participant engagement. Methods We conducted a mixed‐methods study in which an AI health coach, powered by a large language model (LLM), was used to support self‐management for SSc.
Nirali Shah +4 more
wiley +1 more source
Near‐Field Electrospinning Micro‐Printhead Achieves Precise Control of Nanofiber Deposition
Advanced Engineering Materials, EarlyView.A micro‐printhead for near‐field electrospinning enables reproducible deposition of polymer nanofibers with diameters below 50 nm. Systematic parameter studies uncover the mechanisms linking operating conditions to fiber morphology, paving the way for precise and low‐cost nanoscale 3D manufacturing.As a high‐resolution, cost‐effective, and rapid ...
Han Xu, Dario Mager, Jan G. Korvink
wiley +1 more source
, 2011 The tips of growing nerve axons flatten into growth cones, which are responsible for the navigation and elongation of the nerve toward the target. These sequences are of interactions between neurite growth cones dissociated from the sea hare, Aplysia ...
Chi, Hung Lin, Forscher, Paul
core +1 more source
Cell Reports, 2017 Summary: The growth cone is an essential structure for nerve growth. Although its membrane and cytoskeleton are likely to interact coordinately during nerve growth, the mechanisms are unknown due to their close proximity.
Motohiro Nozumi +3 more
doaj +1 more source
Wnt3a increases F-actin levels in growth cones.
, 2015 (A) Two hours treatment with Wnt3a induces F-actin accumulation in growth cones of DRG neurons. Pseudocolor images of growth cones labeled with Phalloidin (bottom panels) highlight the differences in F-actin levels between Wnt3a and control-treated cells.
Eleanna Stamatakou (781280) +2 more
core +1 more source
Molecular mechanisms separating two axonal pathways during embryonic development of the avian optic tectum [PDF]
, 1991 During embryonic development of the avian optic tectum, retinal and tectobulbar axons form an orthogonal array of nerve processes. Growing axons of both tracts are transiently very closely apposed to each other. Despite this spatial proximity, axons from
Kröger, Stephan +3 more
core +1 more source
, 2022 During neurodevelopment, neurons form growth cones, F-actin rich extensions located at the distal end of the neurites. Growth cones allow dendrites and axons to build synaptic connections through a process of neurite guidance whose mechanisms have not ...
CHOQUET, Daniel +4 more
core +1 more source