Results 1 to 10 of about 22,689,717 (333)

Epidermal Growth Factor

open access: yesAnnual Review of Biochemistry, 1972
During the course of the studies on the nerve growth factor of the submaxillary gland of the male mouse (1), it was observed that extracts of these glands, when injected into newborn mice, caused precocious opening of the eyelid and eruption of the incisors. A polypeptide responsible for this effect has been isolated (2).
Graham Carpenter, S Cohen
openaire   +10 more sources

Single Cell Center of Mass for the Analysis of BMP Receptor Heterodimers Distributions

open access: yesJournal of Imaging, 2021
At the plasma membrane, transmembrane receptors are at the interface between cells and their environment. They allow sensing and transduction of chemical and mechanical extracellular signals.
Hendrik Boog   +2 more
doaj   +1 more source

Advances in the correlation between growth factors and proliferative vitreoretinopathy [PDF]

open access: yesGuoji Yanke Zazhi, 2022
Proliferative vitreoretinopathy(PVR)is a common complication of perforation injury and surgery for rhegmatogenous retinal detachment. The pathogenesis of this disease is still unclear.
Zi-Yi Wang   +3 more
doaj   +1 more source

Yap1-2 Isoform Is the Primary Mediator in TGF-β1 Induced EMT in Pancreatic Cancer

open access: yesFrontiers in Oncology, 2021
Pancreatic ductal adenocarcinoma (PDAC) is the most aggressive human malignancy and intrinsically resistant to conventional therapies. YAP1, as a key downstream effector of the Hippo pathway, plays an important role in tumorigenesis including PDAC ...
Chao Gao   +14 more
doaj   +1 more source

ESE1/AGR2 axis antagonizes TGF‐β‐induced epithelial‐mesenchymal transition in low‐grade pancreatic cancer

open access: yesCancer Medicine, 2023
Epithelium‐specific ETS transcription factor 1 (ESE1) has been implicated in epithelial homeostasis, inflammation, as well as tumorigenesis, and cancer progression.
Hui‐Jing Xu   +12 more
doaj   +1 more source

FGF10 and Lipofibroblasts in Lung Homeostasis and Disease: Insights Gained From the Adipocytes

open access: yesFrontiers in Cell and Developmental Biology, 2021
Adipocytes not only function as energy depots but also secrete numerous adipokines that regulate multiple metabolic processes, including lipid homeostasis.
Yu-Qing Lv   +8 more
doaj   +1 more source

FGF1 alleviates LPS-induced acute lung injury via suppression of inflammation and oxidative stress

open access: yesMolecular Medicine, 2022
Background Acute lung injury (ALI) and its severe form, acute respiratory distress syndrome (ARDS), are devastating clinical disorders with high mortality, and for which more effective therapies are urgently needed.
Qhaweni Dhlamini   +11 more
doaj   +1 more source

FGF10 Therapeutic Administration Promotes Mobilization of Injury-Activated Alveolar Progenitors in a Mouse Fibrosis Model

open access: yesCells, 2022
Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease with dire consequences and in urgent need of improved therapies. Compelling evidence indicates that damage or dysfunction of AT2s is of central importance in the development ...
Yu-Qing Lv   +12 more
doaj   +1 more source

Evaluation of PTEN Inhibitor Following Spinal Cord Injury on Recovery of Voiding Efficiency and Motor Function Observed by Regeneration in Spinal Cord [PDF]

open access: yesInternational Neurourology Journal, 2020
Purpose Neurogenic bladder (NB) associated with spinal cord injury (SCI) is a serious health problem. However, no effective treatment has been developed for SCI patients with NB.
Young Sam Cho, Su Jin Kim, Khae Hawn Kim
doaj   +1 more source

Growth factors of random butterfly matrices and the stability of avoiding pivoting [PDF]

open access: yesSIAM Journal on Matrix Analysis and Applications, Volume 44, Issue 3 (2023), 2022
Random butterfly matrices were introduced by Parker in 1995 to remove the need for pivoting when using Gaussian elimination. The growing applications of butterfly matrices have often eclipsed the mathematical understanding of how or why butterfly matrices are able to accomplish these given tasks.
arxiv   +1 more source

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