Results 251 to 260 of about 7,029,797 (363)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Synergistic Effects of Insulin-like Growth Factor-1 and Platelet-Derived Growth Factor-BB in Tendon Healing. [PDF]

Int J Mol Sci
Rieber J, Wolint P, Meier-Bürgisser G, Ongini E, Giovanoli P, Calcagni M, Snedeker JG, Buschmann J.   +7 more
europepmc   +1 more source

Observations on an Unknown Dietary Factor Essential for Human Growth

, 1950
Selma E. Snyderman, L. Emmett Holt, Rosa Lee Nemir, Loren P. Guy, R.M. Carretero, Katherine C. Ketron   +5 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Spinocerebellar Ataxia 27 A with Episodic Ataxia: Case Series of Fibroblast Growth Factor 14 (FGF14) Microdeletions. [PDF]

Cerebellum
Conci E, Kelly TL, Armstrong R, Harijan P, Horvath R.   +4 more
europepmc   +1 more source

Studies on a Growth Factor Present in Polished Rice and Required by Chicks on a Simplified Diet

, 1940
E. L. R. Stokstad, P.D.V. Manning, R.E. Rogers   +2 more
openalex   +1 more source

Factor Decomposition of Sectoral Growth in South Africa, 1970-2007 [PDF]

, 2009
Tregenna, Fiona
core   +2 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Cells Derived from Concentrated Growth Factor Exhibit a Multilineage Differentiation Capacity. [PDF]

Int J Mol Sci
Giannotti L, Calabriso N, Spedicato F, Palermo A, Di Chiara Stanca B, Demitri C, De Sangro MA, Carluccio MA, Damiano F, Siculella L, Stanca E.   +10 more
europepmc   +1 more source

Some Factors Affecting the Growth of Certain Strains of P. Roqueforti Blue Mold. II

, 1926
N. S. Golding
openalex   +1 more source