Results 51 to 60 of about 6,896,550 (362)

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Cross-sectional time series models for identifying the most important factors of e-government growth in Arab countries

Iraqi Journal for Computers and Informatics
The goal of this study was to determine the key elements driving the expansion of e-government in Arab nations. One of the econometric models—the cross-sectional time series model (panel)—was employed to accomplish the intended outcome.
Ban Qasim Al nidawy
doaj   +1 more source

In Vitro Characterization of Hypoxia Preconditioned Serum (HPS)—Fibrin Hydrogels: Basis for an Injectable Biomimetic Tissue Regeneration Therapy

Journal of Functional Biomaterials, 2019
Blood-derived growth factor preparations have long been employed to improve perfusion and aid tissue repair. Among these, platelet-rich plasma (PRP)-based therapies have seen the widest application, albeit with mixed clinical results to date.
Ektoras Hadjipanayi, Philipp Moog, Sanjar Bekeran, Katharina Kirchhoff, Andrei Berezhnoi, Juan Aguirre, Anna-Theresa Bauer, Haydar Kükrek, Daniel Schmauss, Ursula Hopfner, Sarah Isenburg, Vasilis Ntziachristos, Milomir Ninkovic, Hans-Günther Machens, Arndt F. Schilling, Ulf Dornseifer   +15 more
doaj   +1 more source

Growth Pattern and Condition Factor of Yellowfin Tuna Thunnus Albacares (Bonnaterre, 1788) in Eastern Indian Ocean [PDF]

, 2018
Tuna madidihang, Thunnus albacares (Bonnaterre,1788), merupakan salah satu spesies tuna ekonomis penting dan ter-sebar di perairan Indonesia, termasuk di WPP 572 (Samudra Hindia bagian barat Sumatera). Salah satu aspek penting yang berkaitan dengan upaya
Jatmiko, I. (Irwan), Nugroho, S. C. (Suciadi), Wujdi, A. (Arief)   +2 more
core  

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Density pertubation of unparticle dark matter in the flat Universe

, 2009
The unparticle has been suggested as a candidate of dark matter. We investigated the growth rate of the density perturbation for the unparticle dark matter in the flat Universe. First, we consider the model in which unparticle is the sole dark matter and
A. Kiakotou, A.G. Riess, A.L.B. Ribeiro, C. Di Porto, C.X. Zhang, D. Huterer, D. Polarski, E. Bertschinger, E.W. Kolb, G. Ballesteros, H. Davoudiasl, H. Georgi, H. Georgi, H. Wei, I. Laszlo, J.H. He, J.L. Feng, J.R. Mureika, Jiliang Jing, K.M. Cheung, L. Knox, L. Wang, M. Ishak, M. Kunz, M. Sereno, M.C. Kumar, N. Fornengo, P. Bernardis de, P.J.E. Peebles, P.J.E. Peebles, R. Gannouji, S. Daniel, S. Nesseris, S. Perlmutter, S. Perlmutter, S. Weinberg, S. Weinberg, S.L. Chen, Songbai Chen, T. Kikuchi, T. Padmanabhan, V. Acquaviva, V. Sahni, X.G. He, X.G. He, Xiangyun Fu, Y. Gong, Y. Wang, Y.G. Gong, Y.G. Gong   +49 more
core   +1 more source

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Current insights on use of growth factors as therapy for Intervertebral Disc Degeneration

Biomolecular Concepts, 2018
Chronic low back pain is a critical health problem and a leading cause of disability in aging populations. A major cause of low back pain is considered to be the degeneration of the intervertebral disc (IVD). Recent advances in therapeutics, particularly
Kennon Justin C., Awad Mohamed E., Chutkan Norman, DeVine John, Fulzele Sadanand   +4 more
doaj   +1 more source

Microglial Progranulin: Involvement in Alzheimer’s Disease and Neurodegenerative Diseases

Cells, 2019
Neurodegenerative diseases such as Alzheimer’s disease have proven resistant to new treatments. The complexity of neurodegenerative disease mechanisms can be highlighted by accumulating evidence for a role for a growth factor, progranulin (PGRN ...
Anarmaa Mendsaikhan, Ikuo Tooyama, Douglas G. Walker   +2 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source