Results 31 to 40 of about 7,309,384 (308)
Summary: Hepatocellular carcinoma (HCC) is an aggressive primary liver cancer. However, its origin remains a debated question. Using human data and various hepatocarcinogenesis mouse models, we show that, in early stages, transformed hepatocytes ...
Krishna S. Tummala +6 more
doaj +1 more source
SIRT1 Mediates Effects of FGF21 to Ameliorate Cisplatin-Induced Acute Kidney Injury
Acute kidney injury (AKI) is a common complication in cancer patients. Kidney function is closely related to patients’ quality of life and tumor prognosis. Cisplatin is a highly effective anti-tumor drug.
Qiongzhen Chen +7 more
doaj +1 more source
Neovascular growth factors [PDF]
Neovascularisation is the biological process of forming new blood vessels. Many conditions can initiate neovascularisation including trauma or chronic ischaemia produced by diseases such as diabetes. Neovascularisation proceeds through a series of steps beginning with destruction of the basement membrane surrounding the microvascular endothelial cells,
G S, Schultz, M B, Grant
openaire +2 more sources
IL-17A produced by POMC neurons regulates diet-induced obesity
Summary: Overeating leads to obesity, a low-grade inflammatory condition involving interleukin-17A (IL-17A). While pro-opiomelanocortin (POMC) neurons regulate feeding, their connection with IL-17A is not well understood.
Rosa Gallo +3 more
doaj +1 more source
Activity-dependent neuroprotective protein (ADNP) was discovered and first characterized in the laboratory of Prof. Illana Gozes to be regulated by vasoactive intestinal peptide (VIP), and pituitary adenylate cyclase-activating peptide (PACAP) toward ...
Shlomo Sragovich +3 more
doaj +1 more source
During the course of purifying nerve growth factor from the submaxillary gland of the mouse, Cohen (1960) and Levi-Montalcini and Cohen (1960) noticed that daily injections of certain gland extract fractions into newborn mice produced developmental changes that could not be ascribed to nerve growth factor.
G, Carpenter, S, Cohen
openaire +3 more sources
Beyond Metropolitan Startup Rates: Regional Factors Associated with Startup Growth [PDF]
Understanding what fosters -- and hinders -- firm formation and growth at the metropolitan level across the United States is a challenge. Entrepreneurship can be measured by a variety of indicators, and they each can tell somewhat different stories ...
Jordan Bell-Masterson, Yasuyuki Motoyama
core +1 more source
Treatment Decision‐Making Roles and Preferences Among Adolescents and Young Adults With Cancer
ABSTRACT Background Decision‐making (DM) dynamics between adolescents and young adults (AYAs) with cancer, parents, and oncologists remain underexplored in diverse populations. We examined cancer treatment DM preferences among an ethnically and socioeconomically diverse group of AYAs and their parents.
Amanda M. Gutierrez +14 more
wiley +1 more source
The Factors Affecting Growth and Development of Toddler (Age 1-3 Years) with History of Low Birth Weight Infant [PDF]
Background : Low birth weight (LBW) babies would have growth and development disorder in his life. Growth and development in toddler age (1-3 years) are influenced by various factors. This study aims to determine the relationship between sex, nutritional
Girsang, B. M. (Bina) +2 more
core
Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano +7 more
wiley +1 more source

