Results 41 to 50 of about 26,786,639 (354)

SIRT1 Mediates Effects of FGF21 to Ameliorate Cisplatin-Induced Acute Kidney Injury

Frontiers in Pharmacology, 2020
Acute kidney injury (AKI) is a common complication in cancer patients. Kidney function is closely related to patients’ quality of life and tumor prognosis. Cisplatin is a highly effective anti-tumor drug.
Qiongzhen Chen, Junfeng Ma, Xiaoning Yang, Qinyao Li, Zhuofeng Lin, Zhuofeng Lin, Fanghua Gong, Fanghua Gong   +7 more
doaj   +1 more source

VIP/PACAP-Based Drug Development: The ADNP/NAP-Derived Mirror Peptides SKIP and D-SKIP Exhibit Distinctive in vivo and in silico Effects

Frontiers in Cellular Neuroscience, 2020
Activity-dependent neuroprotective protein (ADNP) was discovered and first characterized in the laboratory of Prof. Illana Gozes to be regulated by vasoactive intestinal peptide (VIP), and pituitary adenylate cyclase-activating peptide (PACAP) toward ...
Shlomo Sragovich, Noy Amram, Adva Yeheskel, Illana Gozes   +3 more
doaj   +1 more source

Modern Integrated Associations: Comparative Analysis of Economic Growth Factors [PDF]

, 2015
In the article, the results of the research, which purpose is to ground and assess the factors of economic growth of regional integration communities and national economies of member countries that develop them, are presented.
Doroshenko, S. V., Khusainov, B. D., Shelomentsev, A. G.   +2 more
core   +2 more sources

Growth and Growth Factors [PDF]

Yearbook of Paediatric Endocrinology, 2014
The majority of articles selected for this chapter refer to novel pathophysiological mechanisms that have recently been elucidated. Levels of expression and methylation as well as specific polymorphisms in the IGF2 gene were shown to play a key role not only in fetal growth but also in early postnatal weight gain.
Inzaghi, Elena, Cianfarani, Stefano
openaire   +1 more source

Growth factor and pro-inflammatory cytokine contents in platelet-rich plasma (PRP), plasma rich in growth factors (PRGF), advanced platelet-rich fibrin (A-PRF), and concentrated growth factors (CGF)

International Journal of Implant Dentistry, 2016
BackgroundThe development of platelet-rich fibrin (PRF) drastically simplified the preparation procedure of platelet-concentrated biomaterials, such as platelet-rich plasma (PRP), and facilitated their clinical application.
Hideo Masuki, T. Okudera, Taisuke Watanebe, Masashi Suzuki, Kazuhiko Nishiyama, Hajime Okudera, K. Nakata, Kohya Uematsu, C. Su, T. Kawase   +9 more
semanticscholar   +1 more source

Role of insulin-like growth factors in embryonic and postnatal growth.

Cell, 1993
A developmental analysis of growth kinetics in mouse embryos carrying null mutations of the genes encoding insulin-like growth factor I (IGF-I), IGF-II, and the type 1 IGF receptor (IGF1R), alone or in combination, defined the onset of mutational effects
J. Baker, Jeh-Ping Liu, E. Robertson, A. Efstratiadis   +3 more
semanticscholar   +1 more source

Clinical Application of Growth Factors and Cytokines in Wound Healing

Wound Repair and Regeneration, 2014
Wound healing is a complex and dynamic biological process that involves the coordinated efforts of multiple cell types and is executed and regulated by numerous growth factors and cytokines.
Stephan Barrientos, H. Brem, Olivera Stojadinović, M. Tomic‐Canic   +3 more
semanticscholar   +1 more source

Why and When Are Evidence‐Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie, Kara A. Gray‐Burrows, Peter F. Day, Bob Phillips, Carl A. Thompson   +4 more
wiley   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source