Results 31 to 40 of about 3,184,534 (315)

SIRT1 Mediates Effects of FGF21 to Ameliorate Cisplatin-Induced Acute Kidney Injury

Frontiers in Pharmacology, 2020
Acute kidney injury (AKI) is a common complication in cancer patients. Kidney function is closely related to patients’ quality of life and tumor prognosis. Cisplatin is a highly effective anti-tumor drug.
Qiongzhen Chen, Junfeng Ma, Xiaoning Yang, Qinyao Li, Zhuofeng Lin, Zhuofeng Lin, Fanghua Gong, Fanghua Gong   +7 more
doaj   +1 more source

VIP/PACAP-Based Drug Development: The ADNP/NAP-Derived Mirror Peptides SKIP and D-SKIP Exhibit Distinctive in vivo and in silico Effects

Frontiers in Cellular Neuroscience, 2020
Activity-dependent neuroprotective protein (ADNP) was discovered and first characterized in the laboratory of Prof. Illana Gozes to be regulated by vasoactive intestinal peptide (VIP), and pituitary adenylate cyclase-activating peptide (PACAP) toward ...
Shlomo Sragovich, Noy Amram, Adva Yeheskel, Illana Gozes   +3 more
doaj   +1 more source

Glycosaminoglycan synthesis and shedding induced by growth factors are cell and compound specific

, 2007
The interactions between growth factors and sulphated glycosaminoglycans (GAG) have been extensively studied. the aim of this study is to investigate if growth factors would show specificity of action on the synthesis and shedding of sulphated GAG, using
Suarez, Eloah R., Mataveli, Fabio [UNIFESP], De Matos, Leandro L., Nohara, Angela S. [UNIFESP], Pinhal, Maria Aparecida da Silva [UNIFESP], Nader, Helena Bonciani [UNIFESP]   +5 more
core   +1 more source

Growth factor regulation of growth factor production by multiple gene transfer to chondrocytes

, 2013
Of the many classes of molecules regulated by growth factors, growth factors themselves are not well investigated. We tested the hypothesis that combinations of endogenous growth factors interactively regulate the production of other growth factors ...
Trippel, Stephen B., Shi, Shuiliang, Eckert, George J., Mercer, Scott   +3 more
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Growth factors and lipid transport in early mammalian development

, 1990
The insulin-like growth factors (IGFs) are broadly distributed in the human conceptus and are thought to play a role in the growth and differentiation of tissues during development.
Brice, Amy L.
core   +1 more source

Key factors influencing the sustained growth of high-tech SMEs in South Korea - the perspectives of founder owner-managers [PDF]

, 2023
Purpose This paper explores key factors influencing high performing, sustained growth, high-tech small and medium-sized enterprises (SMEs) in South Korea.
Park, C., McQuaid, R., Mawson, S.
core   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Growth and Growth Factors [PDF]

Yearbook of Paediatric Endocrinology, 2014
The majority of articles selected for this chapter refer to novel pathophysiological mechanisms that have recently been elucidated. Levels of expression and methylation as well as specific polymorphisms in the IGF2 gene were shown to play a key role not only in fetal growth but also in early postnatal weight gain.
Inzaghi, Elena, Cianfarani, Stefano
openaire   +1 more source