Results 31 to 40 of about 14,563,375 (182)
[14C]-Tryptophan Metabolic Tracing in Liver Cancer Cells
Bio-Protocol, 2015 Nicotinamide adenine dinucleotide (NAD+) is a coenzyme for many NAD+-consuming proteins with diverse biological functions. Oscillations in NAD+ levels may influence several cellular signaling pathways.
Krishna Tummala, Nabil Djouder
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Frontiers in Bioengineering and Biotechnology, 2021 In this study, the optimum human aFGF gene encoding haFGF135 was cloned in pET3c and transferred to Escherichia coli BL21(DE3) plysS. To enhance the yield of fermentation and the expression level of the target protein, the fermentation parameters ...
Bingjie Yu +14 more
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Myocardial protection by heparin-based coacervate of FGF10
Bioactive Materials, 2021 Heart disease is still the leading killer all around the world, and its incidence is expected to increase over the next decade. Previous reports have already shown the role of fibroblast growth factor10 (FGF10) in alleviating heart diseases.
Zhouguang Wang +7 more
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, 1975 http://babel.hathitrust.org/cgi/pt?id=mdp.39015007423828;view=2up;ui=fullscreen#page/n0/mode ...
Symposium on Craniofacial Growth
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Frontiers in Pharmacology, 2021 Podocytes are essential components of the glomerular basement membrane. Epithelial-mesenchymal-transition (EMT) in podocytes results in proteinuria. Fibroblast growth factor 1 (FGF1) protects renal function against diabetic nephropathy (DN).
Dezhong Wang +13 more
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Growth Factor Regulation of Growth Factors in Articular Chondrocytes [PDF]
Journal of Biological Chemistry, 2009 Several lines of evidence indicate that polypeptide growth factors are important in articular cartilage homeostasis and repair. It is not yet clear how these growth factors are regulated. We tested the hypothesis that the growth factors responsible for regulating cartilage are themselves regulated by growth factors.
Shuiliang, Shi +3 more
openaire +2 more sources
Frontiers in Pharmacology, 2023 Introduction: Recombinant human fibroblast growth factor 21 (FGF-21) is a potential therapeutic agent for multiple metabolic diseases. However, little is known about the toxicokinetic characteristics of FGF-21.Methods: In the present study, we ...
Chao Lu +17 more
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IL-17A produced by POMC neurons regulates diet-induced obesity
iScienceSummary: Overeating leads to obesity, a low-grade inflammatory condition involving interleukin-17A (IL-17A). While pro-opiomelanocortin (POMC) neurons regulate feeding, their connection with IL-17A is not well understood.
Rosa Gallo +3 more
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Cell Reports, 2017 Summary: Hepatocellular carcinoma (HCC) is an aggressive primary liver cancer. However, its origin remains a debated question. Using human data and various hepatocarcinogenesis mouse models, we show that, in early stages, transformed hepatocytes ...
Krishna S. Tummala +6 more
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FGF21 Attenuated LPS-Induced Depressive-Like Behavior via Inhibiting the Inflammatory Pathway
Frontiers in Pharmacology, 2020 Major depressive disorder is a serious neuropsychiatric disorder with high rates of recurrence and mortality. Many studies have supported that inflammatory processes play a central role in the etiology of depression.
Xue Wang +15 more
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