Results 21 to 30 of about 14,563,375 (182)
Endocrine Journal, 2023 Measurements of serum insulin-like growth factor 1 (IGF-1) levels are useful surrogate markers for the diagnosis and management of patients with growth hormone-related disorders.
Tsuyoshi Isojima, Akira Shimatsu
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Advances in the Relationship Between Pyroptosis and Diabetic Neuropathy
Frontiers in Cell and Developmental Biology, 2021 Pyroptosis is a novel programmed cell death process that promotes the release of interleukin-1β (IL-1β) and interleukin-18 (IL-18) by activating inflammasomes and gasdermin D (GSDMD), leading to cell swelling and rupture.
Jingyu Xu +7 more
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Growth, growth factors and diabetes [PDF]
European Journal of Endocrinology, 2004 Type 1 diabetes mellitus (T1DM) and other chronic diseases in children are well known to adversely affect linear growth and pubertal development. In the years immediately following the introduction of insulin therapy, short stature was consistently reported in children with T1DM.
CHIARELLI, Francesco +2 more
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A comprehensive analysis of prefoldins and their implication in cancer
iScience, 2021 Summary: Prefoldins (PFDNs) are evolutionary conserved co-chaperones, initially discovered in archaea but universally present in eukaryotes. PFDNs are prevalently organized into hetero-hexameric complexes.
Irene Herranz-Montoya +2 more
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Frontiers in Cell and Developmental Biology, 2020 Diabetes significantly induces cognitive dysfunction. Neuronal apoptosis is the main cause of diabetes-induced cognitive decline (DICD). Apoptosis signal-regulating kinase 1 (ASK1) and endoplasmic reticulum (ER) stress are remarkably activated by ...
Yanqing Wu +13 more
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Materials & Design, 2021 Osteoarthritis (OA) is one of the most common chronic diseases, causing degenerative changes in articular cartilage and subchondral bones. To date, there is no effective drug to delay the progression of OA in clinical practice.
Rongshuai Yang +8 more
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Diet, Microbiota, and Colorectal Cancer
iScience, 2019 The intestinal epithelium is a very dynamic tissue under a high regenerative pressure, which makes it susceptible to malignant transformation. Proper integration of various cell signaling pathways and a balanced cross talk between different cell types ...
Tatiana P. Grazioso +2 more
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Detection of chromosome instability by interphase FISH in mouse and human tissues
STAR Protocols, 2021 Summary: Chromosomal instability (CIN), a type of genomic instability, favors changes in chromosome number and structure and it is associated with the progression and initiation of multiple diseases, including cancer.
Raul Torres-Ruiz +5 more
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The forgotten art of cold therapeutic properties in cancer: A comprehensive historical guideGlossary
iScience, 2023 Summary: Cold therapy has been used for centuries, from Julius Caesar to Mohandas Gandhi, as a potent therapeutic approach. However, it has been largely forgotten in modern medicine.
Tatiana P. Grazioso, Nabil Djouder
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Cell Reports Medicine, 2020 Summary: Enteroviruses are suspected to contribute to insulin-producing β cell loss and hyperglycemia-induced diabetes. However, mechanisms are not fully defined.
Hugo Bernard +7 more
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