Results 11 to 20 of about 26,786,639 (354)

Advances in the Relationship Between Pyroptosis and Diabetic Neuropathy

Frontiers in Cell and Developmental Biology, 2021
Pyroptosis is a novel programmed cell death process that promotes the release of interleukin-1β (IL-1β) and interleukin-18 (IL-18) by activating inflammasomes and gasdermin D (GSDMD), leading to cell swelling and rupture.
Jingyu Xu, Shufang Cai, Jiaxin Zhao, Ke Xu, Hao Ji, Chengbiao Wu, Jian Xiao, Yanqing Wu   +7 more
doaj   +1 more source

A comprehensive analysis of prefoldins and their implication in cancer

iScience, 2021
Summary: Prefoldins (PFDNs) are evolutionary conserved co-chaperones, initially discovered in archaea but universally present in eukaryotes. PFDNs are prevalently organized into hetero-hexameric complexes.
Irene Herranz-Montoya, Solip Park, Nabil Djouder   +2 more
doaj   +1 more source

The Reciprocal Causation of the ASK1-JNK1/2 Pathway and Endoplasmic Reticulum Stress in Diabetes-Induced Cognitive Decline

Frontiers in Cell and Developmental Biology, 2020
Diabetes significantly induces cognitive dysfunction. Neuronal apoptosis is the main cause of diabetes-induced cognitive decline (DICD). Apoptosis signal-regulating kinase 1 (ASK1) and endoplasmic reticulum (ER) stress are remarkably activated by ...
Yanqing Wu, Yanqing Wu, Yuan Yuan, Chengbiao Wu, Ting Jiang, Beini Wang, Jun Xiong, Peipei Zheng, Yiyang Li, Jingyu Xu, Ke Xu, Yaqian Liu, Xiaokun Li, Jian Xiao   +13 more
doaj   +1 more source

Modified poloxamer 407 and hyaluronic acid thermosensitive hydrogel-encapsulated keratinocyte growth factor 2 improves knee osteoarthritis in rats

Materials & Design, 2021
Osteoarthritis (OA) is one of the most common chronic diseases, causing degenerative changes in articular cartilage and subchondral bones. To date, there is no effective drug to delay the progression of OA in clinical practice.
Rongshuai Yang, Min Chen, Xuanxin Yang, Wenzhe Sun, Chao Lu, Qi Hui, Changcan Shi, Xiaokun Li, Xiaojie Wang   +8 more
doaj   +1 more source

Hepatic regeneration and growth factors [PDF]

, 1993
Nessun ...
Azzarone, A, Barone, M, Francavilla, A, Polimeno, L, Starzl, TE   +4 more
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Diet, Microbiota, and Colorectal Cancer

iScience, 2019
The intestinal epithelium is a very dynamic tissue under a high regenerative pressure, which makes it susceptible to malignant transformation. Proper integration of various cell signaling pathways and a balanced cross talk between different cell types ...
Tatiana P. Grazioso, Marta Brandt, Nabil Djouder   +2 more
doaj   +1 more source

Detection of chromosome instability by interphase FISH in mouse and human tissues

STAR Protocols, 2021
Summary: Chromosomal instability (CIN), a type of genomic instability, favors changes in chromosome number and structure and it is associated with the progression and initiation of multiple diseases, including cancer.
Raul Torres-Ruiz, Tatiana P. Grazioso, Marta Brandt, Marta Martinez-Lage, Sandra Rodriguez-Perales, Nabil Djouder   +5 more
doaj   +1 more source

Growth factors and experimental arterial grafts [PDF]

, 2016
Background: The production of growth factors from several experimental arterial conduits was determined. Methods: We implanted 105 experimental arterial grafts that were 1 cm long in the abdominal aorta of Lewis rats (average weight, 250 g).
BORRELLI, Valeria, CUCINA, Alessandra, DI MARZO, Luca, Lepidi, Sandro, SAPIENZA, Paolo, STERPETTI, ANTONIO, VENTURA, Marco   +6 more
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The forgotten art of cold therapeutic properties in cancer: A comprehensive historical guideGlossary

iScience, 2023
Summary: Cold therapy has been used for centuries, from Julius Caesar to Mohandas Gandhi, as a potent therapeutic approach. However, it has been largely forgotten in modern medicine.
Tatiana P. Grazioso, Nabil Djouder
doaj   +1 more source

Dynamics of growth factor production in monolayers of cancer cells and evolution of resistance to anticancer therapies [PDF]

, 2013
Tumor heterogeneity is well documented for many characters, including the production of growth factors, which improve tumor proliferation and promote resistance against apoptosis and against immune reaction.
Achilles, Aktipis, Aktipis, Amit, André, Archetti, Archetti, Archetti, Archetti, Archetti, Archetti, Armitage, Ashley, Axelrod, Basanta, Basanta, Basanta, Basanta, Basanta, Boza, Byrne, Cairns, Charles, Chuang, Crespi, Crespi, Dexter, Dingli, Durrett, Eungdamrong, Fisher, Foster, Frank, Gatenby, Gatenby, Gerstung, Gonzalez-Garcia, Greaves, Hanahan, Hardin, Hauert, Hemker, Ifti, Iwasa, Jouanneau, Knudson, Lambert, Maley, Marusyk, Maynard Smith, Mendes, Merlo, Motro, Nagy, Nordling, Nowell, Ohtsuki, Pacheco, Palfrey, Pepper, Perc, Rapoport, Ricard, Sugden, Tomlinson, Tomlinson, Traulsen, Traulsen   +67 more
core   +1 more source