Results 61 to 70 of about 3,184,534 (315)
Growth and Growth Factors [PDF]
The last year has again seen some major advances in the Growth and Growth Factors field. Significant advances have been made in our understanding of the genetics of growth. For example, mutations in the pericentrin gene PCNT are associated with both primordial dwarfism and Seckel syndrome.
Evelien F. Gevers, Mehul T. Dattani
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
NAP protects memory, increases soluble tau and reduces tau hyperphosphorylation in a tauopathy model
NAP (NAPVSIPQ) provides broad neuroprotection through microtubule interaction. Here, NAP was investigated for neuroprotection in an in vivo tauopathy model.
Natalia Shiryaev +6 more
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021. [PDF]
BACKGROUND: Understanding the health consequences associated with exposure to risk factors is necessary to inform public health policy and practice. To systematically quantify the contributions of risk factor exposures to specific health outcomes, the ...
GBD 2021 Risk Factors Collaborators +1 more
core +1 more source
Diabetes hinders nerve recovery after spinal cord injury (SCI). The complex pathological factors of diabetes increase the difficulty of treating diabetes combined with SCI. Maintaining normal microglial function is essential for SCI recovery. However, it
Jingyu Xu +14 more
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
The effects of serial correlation on the curve-of-factors growth model [PDF]
textThis simulation study examined the performance of the curve-of-factors growth model when serial correlation and growth processes were present in the first-level factor structure. As previous research has shown (Ferron, Dailey, & Yi, 2002; Kwok,
Murphy, Daniel Lee
core
末梢血から作製したConcentrated Growth Factorsが抜歯創治癒に与える影響 [PDF]
大阪歯科大学Osaka Dental University博士(歯学)This study investigated the effects of Concentrated Growth Factors (CGF) on extraction wound healing using beagle dogs.
岡森, 大典 +2 more
core +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source

