Results 81 to 90 of about 6,173,170 (321)

Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation [PDF]

, 2010
Study found that treatment with recombinant human growth hormone gave significantly greater benefits in stature for children with growth hormone deficiency (GHD), Turner syndrome, Prader–Willi syndrome, chronic renal insufficency, short stature homeobox ...
Bird, A., Baxter, L, Gospodarevskaya, E., K Welch, Cooper, Keith, L Baxter, Frampton, G. K., A Bird, Frampton, GK, Gospodarevskaya, Elena, Gospodarevskaya, E, Welch, K, Bryant, J, Takeda, A, Frampton, G.K., Cooper, K., GK Frampton, Takeda, Andrea, Bird, A, Bryant, J., J Bryant, K Cooper, Welch, Karen, Welch, K., Baxter, L., Takeda, A., Bryant, Jackie, A Takeda, E Gospodarevskaya, Cooper, K   +29 more
core   +1 more source

Renal growth hormone--insulin-like growth factor-I system in acute renal failure.

Kidney International, 1995
The renal growth hormone--insulin-like growth factor-I system in acute ischemic renal failure. Recovery from acute tubular necrosis (ATN) is accelerated by IGF-I therapy.
T. Tsao, Jin Wang, F. Fervenza, T. Vu, Isabella H. Jin, A. Hoffman, R. Rabkin   +6 more
semanticscholar   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Leptin Level in Newly Diagnosed Iraqi Acromegaly Patients

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2018
Acromegaly is a serious endocrine disease resulting from an increase of growth hormone in the blood. Excessive growth hormone secretion may be caused by an adenoma of the pituitary.
Noor Thair Tahir
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Osteosarcoma associated with diamond-blackfan anaemia: a case of a child receiving growth hormone therapy [PDF]

, 2004
Purpose: Diamond–Blackfan anaemia (DBA) is a rare pure congenital red cell aplasia, usually presenting in infancy or early childhood. The literature suggests a predisposition to haemopoietic malignancy but in addition solid tumours have been reported ...
Briggs, TW, Pringle, J, Lee, RS, Higgs, D, Haddo, O   +4 more
core  

The exon3-deleted growth hormone receptor gene polymorphism (d3-GHR) is associated with insulin and spontaneous growth in short SGA children (NESGAS)

, 2017
Objective The effect of a common polymorphism in the Growth Hormone (GH) receptor (d3-GHR) gene on growth, metabolism and body composition was examined in short children born small for gestational age (SGA) on GH treatment.
Thankamony, Ajay, Dunger, David B., Mathilde Gersel Wegmann, Roche, Edna,, Ivarsson, Sten A., Roche, E, Ajay Thankamony, Hoey, Hilary,, Kirk, Jeremy, Ivarsson, Sten-A., Thankamony, A, Rikke Beck Jensen, Jeremy Kirk, Thankamony, Ajay,, Roche, Edna, Juul, Anders,, Söder, Olle, Jensen, Rikke Beck,, Wegmann, Mathilde Gersel, David B. Dunger, Ivarsson, Sten A.,, Ivarsson, Sten-A, Soder, O, Jensen, Rikke Beck, Juul, A, Guftar Shaikh, Söder, Olle,, Edna Roche, Hoey, Hilary, Hoey, H, Kirk, J, Dunger, DB, Kirk, Jeremy,, Dunger, David B, Sten-A. Ivarsson, Anders Juul, Ivarsson, S-A, Wegmann, MG, Hilary Hoey, Juul, Anders, Shaikh, Guftar, Wegmann, Mathilde Gersel,, Dunger, David B.,, Shaikh, Guftar,, Lund University., Shaikh, G, Olle Söder   +46 more
core   +1 more source

The GH-IGF-I axis and breast cancer [PDF]

, 2012
MD (Res)Breast cancer remains one of the most common causes of death amongst women today. Worldwide approximately 1.3 million women are diagnosed as having breast cancer every year.
Laban, Christiana
core   +4 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source