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The Growth Hormone/Prolactin Receptor Family
1993Publisher Summary This chapter provides an overview of growth hormone (GH) and prolactin receptor (PRL) family. Sequence analysis has confirmed that GH and PRL have selected regions of strong homology and, along with placental lactogen (PL) or chorionic somatotropin (CS), form a family of polypeptide hormones that appear to have arisen by the ...
P.A. KELLY +10 more
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Regulation of Growth Hormone Receptor Turnover by Growth Hormone
Acta Paediatrica, 1990Z, Hochberg +4 more
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Annales d'endocrinologie, 1990
Specific binding sites for growth hormone (GH) have been found in a variety of tissues. The rabbit liver GH receptor has recently been purified, sequenced and cloned. It is a polypeptide chain of 620 aminoacids with a single transmembrane domain. The sequence of the extracellular hormone binding domain of the receptor is identical to the sequence of ...
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Specific binding sites for growth hormone (GH) have been found in a variety of tissues. The rabbit liver GH receptor has recently been purified, sequenced and cloned. It is a polypeptide chain of 620 aminoacids with a single transmembrane domain. The sequence of the extracellular hormone binding domain of the receptor is identical to the sequence of ...
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Prolactin and growth hormone receptors
Clinical Endocrinology, 1996V, Goffin, P A, Kelly
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Growth hormone secretagogue receptor antagonists.
Expert opinion on therapeutic patents, 2012The patent claims peptidic/nonpeptidic inhibitors of the ghrelin receptor, the growth hormone secretagogue receptor (GHSR) 1A. Among these compounds, it was disclosed that the addition in some compounds of a GlyMetAla tripeptide at the N-terminus of the ghrelin peptide agonists converts them into ghrelin receptor antagonists.
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The growth hormone receptor and growth hormone sensitivity in man
2008It is well established that the response to endogenous and exogenous growth hormone (GH) varies between individuals. For example, conditions with increased catabolic rate, such as trauma, sepsis and surgery, are believed to be associated with acquired GH insensitivity.
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Signaling pathways activated by the growth hormone receptor
Trends in Endocrinology and Metabolism, 2001Christin Carter-Su +2 more
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