Results 21 to 30 of about 324,189 (163)

Effects of low salinity on epigenetic changes of growth hormone and growth hormone receptor in half smooth tongue sole (Cynoglossus semilaevis)

Reproduction and Breeding, 2021
Salinity is a crucial factor in marine teloest growth. Growth hormone (GH) and growth hormone receptor 1 (GHR1) are crucial regulators of somatic growth and development in teleosts, and may be involved in the mechanisms which drive growth sexual ...
Yufeng Si, Feng He, Haishen Wen, Siping Li, Huiwen He   +4 more
doaj   +1 more source

The Growth Hormone Receptor

Comprehensive Physiology, 1998
Abstract The sections in this article are: Cloning of the Receptor The Hematopoietic Cytokine Receptor Family The Crystal Structure of the Growth Hormone Receptor and its Complex ...
openaire   +3 more sources

Novel mechanisms of growth hormone regulation: growth hormone-releasing peptides and ghrelin

Brazilian Journal of Medical and Biological Research, 2006
Growth hormone secretion is classically modulated by two hypothalamic hormones, growth hormone-releasing hormone and somatostatin. A third pathway was proposed in the last decade, which involves the growth hormone secretagogues.
A.-M.J. Lengyel
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Hormone Receptor Expression Analyses in Neoplastic and Non-Neoplastic Canine Mammary Tissue by a Bead Based Multiplex Branched DNA Assay: A Gene Expression Study in Fresh Frozen and Formalin-Fixed, Paraffin-Embedded Samples. [PDF]

PLoS ONE, 2016
Immunohistochemistry (IHC) is currently considered the method of choice for steroid hormone receptor status evaluation in human breast cancer and, therefore, it is commonly utilized for assessing canine mammary tumors.
Annika Mohr, Florenza Lüder Ripoli, Susanne Conradine Hammer, Saskia Willenbrock, Marion Hewicker-Trautwein, Zdzisław Kiełbowicz, Hugo Murua Escobar, Ingo Nolte   +7 more
doaj   +1 more source

The growth hormone secretagogue receptor

Growth Hormone & IGF Research, 1999
The specific human growth hormone (GH) secretagogue receptor (type la) was cloned in 1996 using the nonpeptide GH secretagogue MK-0677 as a ligand. 1,2 It belongs to the G-protein coupled seven transmembrane domain receptor family, but does not show close homology with any of the known subgroups of receptors, though its sequence is conserved between ...
KORBONITS M., CICCARELLI E., GHIGO, Ezio, GROSSMAN AB   +3 more
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Compound heterozygosity for two GHR missense mutations in a patient affected by Laron Syndrome: a case report

Italian Journal of Pediatrics, 2017
Background Mutations localized in the Growth Hormone Receptor (GHR) gene are often associated with the pathogenesis of Laron Syndrome, an autosomal recessive hereditary disorder characterized by severe growth retardation.
Stefania Moia, Daniele Tessaris, Silvia Einaudi, Luisa de Sanctis, Gianni Bona, Simonetta Bellone, Flavia Prodam   +6 more
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Structural basis for activation of the growth hormone-releasing hormone receptor

Nature Communications, 2020
Growth hormone-releasing hormone (GHRH) controls metabolism and tissue growth through binding to the cognate receptor (GHRHR). Here authors report the structure of the human GHRHR bound to its endogenous ligand and the stimulatory G protein which reveals
Fulai Zhou, Huibing Zhang, Zhaotong Cong, Li-Hua Zhao, Qingtong Zhou, Chunyou Mao, Xi Cheng, Dan-Dan Shen, Xiaoqing Cai, Cheng Ma, Yuzhe Wang, Antao Dai, Yan Zhou, Wen Sun, Fenghui Zhao, Suwen Zhao, Hualiang Jiang, Yi Jiang, Dehua Yang, H. Eric Xu, Yan Zhang, Ming-Wei Wang   +21 more
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Mechanisms Underlying the Synergistic Action of Insulin and Growth Hormone on IGF-I and -II Expression in Grass Carp Hepatocytes

Frontiers in Endocrinology, 2018
In mammals, insulin is known to modify growth hormone (GH)-induced IGF-I expression at the hepatic level, which also contributes to the functional crosstalk between energy homeostasis and somatotropic axis. However, the studies on the comparative aspects
Quan Jiang, Quan Jiang, Jin Bai, Mulan He, Karen W. Y. Yuen, Anderson O. L. Wong   +5 more
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Exploring the growth hormone and growth hormone receptor gene families in rainbow trout (Oncorhynchus mykiss): A genome-wide perspective

In Silico Research in Biomedicine
The growth hormone (GH) and growth hormone receptor (GHR) system is a central regulator of growth and metabolism in vertebrates, with critical implications for aquaculture productivity and functional genomics research.
Neethi Ajith, Urwah Farooq, Tabinda Waheed, Suvadip Ghara, Somasundaram Iyyappan, Irfan Ahmad Bhat, Irfan Ahmad Khan, Mohd Ashraf Rather   +7 more
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The Growth Hormone Receptor: Mechanism of Receptor Activation, Cell Signaling, and Physiological Aspects

Frontiers in Endocrinology, 2018
The growth hormone receptor (GHR), although most well known for regulating growth, has many other important biological functions including regulating metabolism and controlling physiological processes related to the hepatobiliary, cardiovascular, renal ...
Farhad Dehkhoda, Christine M. M. Lee, Johan Medina, Andrew J. Brooks   +3 more
doaj   +1 more source