Results 31 to 40 of about 6,616,948 (200)

Gestation Regulates Growth Hormone and Its Receptor Expression in Sheep Immune Organs

Biology
There are multiple adaptations in maternal physiology, hormones, and immunology during pregnancy. Growth hormone (GH) is not only produced by the pituitary but also secreted by extra-pituitary tissues.
Zhouyuan Li, Xiaoxin Ma, Ziwang Du, Jingjing Li, Leying Zhang, Ling Yang   +5 more
doaj   +1 more source

Novel mechanisms of growth hormone regulation: growth hormone-releasing peptides and ghrelin

Brazilian Journal of Medical and Biological Research, 2006
Growth hormone secretion is classically modulated by two hypothalamic hormones, growth hormone-releasing hormone and somatostatin. A third pathway was proposed in the last decade, which involves the growth hormone secretagogues.
A.-M.J. Lengyel
doaj   +1 more source

Ghrelin Decreases Firing Activity of Gonadotropin-Releasing Hormone (GnRH) Neurons in an Estrous Cycle and Endocannabinoid Signaling Dependent Manner. [PDF]

, 2013
The orexigenic peptide, ghrelin is known to influence function of GnRH neurons, however, the direct effects of the hormone upon these neurons have not been explored, yet.
Farkas, Imre, Liposits, Zsolt, Vastagh, Csaba, Sárvári, Miklós   +3 more
core   +3 more sources

Hormone Receptor Expression Analyses in Neoplastic and Non-Neoplastic Canine Mammary Tissue by a Bead Based Multiplex Branched DNA Assay: A Gene Expression Study in Fresh Frozen and Formalin-Fixed, Paraffin-Embedded Samples. [PDF]

PLoS ONE, 2016
Immunohistochemistry (IHC) is currently considered the method of choice for steroid hormone receptor status evaluation in human breast cancer and, therefore, it is commonly utilized for assessing canine mammary tumors.
Annika Mohr, Florenza Lüder Ripoli, Susanne Conradine Hammer, Saskia Willenbrock, Marion Hewicker-Trautwein, Zdzisław Kiełbowicz, Hugo Murua Escobar, Ingo Nolte   +7 more
doaj   +1 more source

The role of Gai in the Gonadotropin-releasing hormone (GnRH) receptor inhibition of cell proliferation [PDF]

, 2011
Includes abstract.Includes bibliographical references (leaves 72-78).The activation of Gonadotropin-releasing hormone receptor (GnRHR) by the GnRH ligand has been shown to mediate antiproliferative effects in extra-pituitary cells and in reproductive ...
Phillips, Pumza Samantha
core   +1 more source

Mechanisms Underlying the Synergistic Action of Insulin and Growth Hormone on IGF-I and -II Expression in Grass Carp Hepatocytes

Frontiers in Endocrinology, 2018
In mammals, insulin is known to modify growth hormone (GH)-induced IGF-I expression at the hepatic level, which also contributes to the functional crosstalk between energy homeostasis and somatotropic axis. However, the studies on the comparative aspects
Quan Jiang, Quan Jiang, Jin Bai, Mulan He, Karen W. Y. Yuen, Anderson O. L. Wong   +5 more
doaj   +1 more source

Growth Hormone (GH)-Releasing Peptide Stimulation of GH Release from Human Somatotroph Adenoma Cells: Interaction with GH-Releasing Hormone, Thyrotropin- Releasing Hormone, and Octreotide. [PDF]

, 1994
The synthetic hexapeptide GH-releasing peptide (GHRP; His-D-Trp-Ala-Trp-D-Phe-Lys-NH2) specifically stimulates GH secretion in humans in vivo and in animals in vitro and in vivo via a still unknown receptor and mechanism.
Strasburger, Christian J., Renner, U., Müller, O., Stalla, G., Brockmeier, S., Schopohl, Jochen, Strasburger, C., Müller, Otto-Albrecht, Schopohl, J., Strasburger, C. J., Werder, K., Lange, M., Werder, K. von, Stalla, G. K., Müller, O. A.   +14 more
core   +1 more source

Structural basis for activation of the growth hormone-releasing hormone receptor

Nature Communications, 2020
Growth hormone-releasing hormone (GHRH) controls metabolism and tissue growth through binding to the cognate receptor (GHRHR). Here authors report the structure of the human GHRHR bound to its endogenous ligand and the stimulatory G protein which reveals
Fulai Zhou, Huibing Zhang, Zhaotong Cong, Li-Hua Zhao, Qingtong Zhou, Chunyou Mao, Xi Cheng, Dan-Dan Shen, Xiaoqing Cai, Cheng Ma, Yuzhe Wang, Antao Dai, Yan Zhou, Wen Sun, Fenghui Zhao, Suwen Zhao, Hualiang Jiang, Yi Jiang, Dehua Yang, H. Eric Xu, Yan Zhang, Ming-Wei Wang   +21 more
doaj   +1 more source

Effects of low salinity on epigenetic changes of growth hormone and growth hormone receptor in half smooth tongue sole (Cynoglossus semilaevis)

Reproduction and Breeding, 2021
Salinity is a crucial factor in marine teloest growth. Growth hormone (GH) and growth hormone receptor 1 (GHR1) are crucial regulators of somatic growth and development in teleosts, and may be involved in the mechanisms which drive growth sexual ...
Yufeng Si, Feng He, Haishen Wen, Siping Li, Huiwen He   +4 more
doaj   +1 more source

Anosmin-1 modulates fibroblast growth factor receptor 1 signaling in human gonadotropin-releasing hormone olfactory neuroblasts through a heparan sulfate-dependent mechanism [PDF]

, 2004
Defects of either anosmin-1 or fibroblast growth factor receptor 1 (FGFR1) are known to underlie hereditary Kallmann's syndrome (KS), a human disorder of olfactory and gonadotropin-releasing hormone (GnRH) neuronal ontogeny.
Guimond, S, Bouloux, PM, Turnbull, Jeremy, Turnbull, J, Hu, Youli, Kim, SH, Kim, Soo-Hyun, Schofield, Jonathan, Winyard, P, Winyard, Paul, Vannelli, GB, Bouloux, Pierre-Marc, Gonzalez-Martinez, D, Hu, YL, Schofield, J, Vannelli, Gabriella Barbara, González-Martínez, David, Guimond, Scott   +17 more
core   +1 more source