Results 111 to 120 of about 60,269 (268)

Predictors of Mortality in Patients With Multiple Endocrine Neoplasia Type 1

Clinical Endocrinology, Volume 103, Issue 1, Page 50-56, July 2025.
SUMMARY Objective Multiple Endocrine Neoplasia Type 1 (MEN 1) is an autosomal dominant disease predisposing to hyperplasia and neoplasia in diverse endocrine tissues. Patients typically present with endocrine abnormalities before the age of 30 years and have reduced life expectancy.
Jasmine J. Zhu, John R Burgess
wiley   +1 more source

Neuroendocrine Regulation of Metabolism [PDF]

, 2016
Given the current environment in most developed countries, it is a challenge to maintain a good balance between calories consumed and calories burned, although maintenance of metabolic balance is key to good health. Therefore, understanding how metabolic
Becu Villalobos, D., Coirini, Hector, Cornejo, María Paula, Elias, C. F., Hentges, S.T., Maliqueo, M.   +5 more
core   +3 more sources

The Essentiality of Amino Acids in Healthiness and Disease State: Type II Diabetes as a Case Study

Food Science &Nutrition, Volume 13, Issue 6, June 2025.
This review investigates the functions of amino acids in normal physiological states, their potential as a diagnostic biomarker, the probable risk of deficiency, and the therapeutic ability for managing and preventing type 2 diabetes mellitus. ABSTRACT A healthy life depends on the availability and the synthesis of amino acids as they are building ...
Samuel Idowu Fayomi, Ochuko Lucky Erukainure, Nontokozo Zimbili Msomi   +2 more
wiley   +1 more source

Hypothalamic Growth Hormone Secretagogue-Receptor (GHS-R) Expression Is Regulated by Growth Hormone in the Rat [PDF]

Endocrinology, 1997
Synthetic GH secretagogues (GHSs) act via a receptor (GHS-R) distinct from that for GH-releasing hormone (GHRH). We have studied the hypothalamic expression and regulation of this receptor by in situ hybridization using a homologous riboprobe for rat GHS-R.
Gregory B. Thomas, Gregory B. Thomas, Pamela A. Bennett, Pamela A. Bennett, Scott D. Feighner, Scott D. Feighner, Lex H.T. Van der Ploeg, Lex H.T. Van der Ploeg, Roy G. Smith, Roy G. Smith, Iain C. A. F. Robinson, Iain C. A. F. Robinson, Andrew D. Howard, Andrew D. Howard   +13 more
openaire   +3 more sources

Ghrelin protects alveolar macrophages against lipopolysaccharide-induced apoptosis through growth hormone secretagogue receptor 1a-dependent c-Jun N-terminal kinase and Wnt/β-catenin signaling and suppresses lung inflammation.

Endocrinology, 2015
Alveolar macrophages (AMs) undergo increased apoptosis during sepsis-induced acute respiratory distress syndrome (ARDS). Ghrelin exhibits an antiapoptotic effect in several cell types and protects against sepsis-induced ARDS in rats; however, the ...
Bin Li, M. Zeng, Wanmei He, Xubin Huang, Liang Luo, Hongwu Zhang, David Y B Deng   +6 more
semanticscholar   +1 more source

Expression pattern of the fused in sarcoma gene and its contextual influence on the density-specific response of the growth hormone/insulin-like growth factor 1 axis in zig-zag eels (Mastacembelus armatus)

Frontiers in Marine Science
The fused in sarcoma (FUS) protein is a DNA/RNA binding protein from the ten-eleven translocation protein family that is associated with neurodegeneration, and it has been shown to promote cell proliferation through the growth hormone/insulin-like growth
Lingzhan Xue, Yu Gao, Songpei Zhang, Manxin Weng, Manxin Weng, Gaoxiong Zeng, Jiajia Chen, Mengxiang Liao, Sayyed Mohammad Hadi Alavi, Yann Guiguen   +9 more
doaj   +1 more source

Integrating solid-state NMR and computational modeling to investigate the structure and dynamics of membrane-associated ghrelin. [PDF]

PLoS ONE, 2015
The peptide hormone ghrelin activates the growth hormone secretagogue receptor 1a, also known as the ghrelin receptor. This 28-residue peptide is acylated at Ser3 and is the only peptide hormone in the human body that is lipid-modified by an octanoyl ...
Gerrit Vortmeier, Stephanie H DeLuca, Sylvia Els-Heindl, Constance Chollet, Holger A Scheidt, Annette G Beck-Sickinger, Jens Meiler, Daniel Huster   +7 more
doaj   +1 more source

Ghrelin; The Renown Hormone [PDF]

, 2006
Ghrelin , a 28 amino acid gastric peptide, was found to be a potent releaser of GH and in addition, actively participate in controlling energy balance and the regulation of food intake. Specifically, plasma ghrelin originates in the oxyntic gland where A-
H. Murat Bilgin
core  

Ghrelin contributes to protection of hepatocellular injury induced by ischaemia/reperfusion [PDF]

, 2013
Background & Aims Ghrelin, a gut hormone with pleiotropic effects, may act as a protective signal in parenchymal cells. We investigated the protective effects of ghrelin on hepatocytes after ischaemia/reperfusion (I/R).
Li, Yin, Li, Ziru, Mulholland, Michael, Qin, Yan, Wang, Zhigang, Zhang, Weizhen, Zhao, Jing   +6 more
core   +1 more source

Cisplatin‐Induced Muscle Wasting and Atrophy: Molecular Mechanism and Potential Therapeutic Interventions

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 3, June 2025.
ABSTRACT Platinum‐based chemotherapeutics, particularly cisplatin, are crucial in the treatment of various malignancies due to their strong antitumor effects. However, a significant side effect of cisplatin is muscle atrophy, which severely impairs physical strength, diminishes quality of life and complicates cancer therapy.
Ko‐Chieh Huang, Yi‐Fen Chiang, Mohamed Ali, Shih‐Min Hsia   +3 more
wiley   +1 more source