Results 111 to 120 of about 10,555 (248)

Molecular characterization of the bovine GHRL gene [PDF]

, 2009
peer reviewedaudience: researcherBovine ghrelin, a 27 amino acid pepticle, has been identified in oxyntic glands of the abomasum. It is an endogenous ligand for growth hormone secretagogue receptor and stimulates food intake and growth hormone secretion.
Colinet, Frédéric, Portetelle, Daniel, Renaville, Robert   +2 more
core   +1 more source

A novel non-peptidic agonist of the ghrelin receptor with orexigenic activity in vivo [PDF]

, 2016
Loss of appetite in the medically ill and ageing populations is a major health problem and a significant symptom in cachexia syndromes, which is the loss of muscle and fat mass. Ghrelin is a gut-derived hormone which can stimulate appetite.
Clarke, Sarah L., Kandil, Dalia, McGlacken, Gerard P., Pardo, Leticia M., Pastor-Cavada, Elena, Schellekens, Harriët, Shaban, Hamdy, Torres-Fuentes, Cristina   +7 more
core   +2 more sources

Nucleus accumbens ghrelin signaling controls anxiety-like behavioral response to acute stress

Behavioral and Brain Functions
Background Anxiety disorders are one of the most common mental disorders. Ghrelin is a critical orexigenic brain-gut peptide that regulates food intake and metabolism.
Leilei Chang, Yecheng He, Tian Tian, Bin Li   +3 more
doaj   +1 more source

Fasting and postprandial plasma ghrelin levels are decreased in patients with liver failure previous to liver transplantation [PDF]

, 2009
[Abstract] Anorexia is a problem of paramount importance in patients with advanced liver failure. Ghrelin has important actions on feeding and weight homeostasis. Concentrations of ghrelin are controversial in liver cirrhosis.
A Asakawa, A Caixas, A Laviano, AJ Lely van der, AL Barkan, AM Haqq, AM Madden, AM Wren, B Otto, C Gauna, C Gauna, C Matos, DE Cummings, DE Cummings, DE Cummings, DE Flanagan, DR Matthews, E Kalaitzakis, ET Vestergaard, F Cordido, F Tacke, Fernando Cordido, FM Toorn Van der, Francisco Suarez, G Marchesini, G Marchesini, G Muccioli, G Murdolo, G Schaller, H Ataseven, H Hosoda, H Takahashi, HIM Davidson, HJ Kim, HU Lautz, I Bedendi, J Kozakowski, J Liu, J Ockenga, Jesús Garcia-Buela, K Toshinai, KE Foster-Schubert, M Breidert, M Granado, M Hotta, M Kojima, M Kojima, M Merli, M Nakazato, M Perez-Fontán, M Perez-Fontán, M Pérez-Fontán, M Tschop, M Tschop, M Tschöp, MA Bednarek, Maria Teresa Diz-Lois, ML Isidro, NM Thompson, O Kasımay, O Selberg, O Ukkola, Ovidio Vidal, P Alvarez, P Cassoni, PU Freda, R Nass, SO Işeri, Susana Sangiao-Alvarellos, T McLaughlin, T Shiiya, V Cappiello, WAM Blom, X Zhu, Y Shuto, Z Jarkovska   +75 more
core   +2 more sources

Effect of acute and regular exercise on growth hormone secretagogue receptor-1a expression in human lymphocytes, T cell subpopulation and monocytes [PDF]

, 2013
Effect of acute and regular exercise on growth hormone secretagogue receptor-1a expression in human lymphocytes, T cell subpopulation and ...
Charlotte Coombs (7247834), David Stensel (1257075), Harumi Hayashida (7242104), Megan Clark (7247831), Nicolette Bishop (1255977), Sean Miller (218704)   +5 more
core   +1 more source

Ghrelin Increases Beta-Catenin Level through Protein Kinase A Activation and Regulates OPG Expression in Rat Primary Osteoblasts. [PDF]

, 2015
Ghrelin, by binding growth hormone secretagogue receptor (GHS-R), promotes osteoblast proliferation but the signaling mechanism of GHS-R on these cells remains unclear. Since canonical Wnt/β-catenin pathway is critically associated with bone homeostasis,
Casati, L, Mrak, E, Pagani, F, Rubinacci, A, Sibilia, V, Zarattini, G   +5 more
core   +4 more sources

The effect of intravenous injection of Ghrelin on the mean plasma concentrations of insulin in immature camels fed different levels of their energy requirements [PDF]

Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2009
Ghrelin is a peptide hormone secreted into the circulation from the stomach, but this peptide is also synthetized in a number of different body tissues including the brain and pancreas, suggesting both endocrine and paracrine effects.
doaj  

The G protein-coupled receptor heterodimer network (GPCR-HetNet) and its hub components [PDF]

, 2014
G protein-coupled receptors (GPCRs) oligomerization has emerged as a vital characteristic of receptor structure. Substantial experimental evidence supports the existence of GPCR-GPCR interactions in a coordinated and cooperative manner.
Agnati, Luigi F, Borroto-Escuela, Dasiel O, Brito, Ismel, Di Palma, Michael, Duchou, Jolien, Fuxe, Kjell, Guidolin, Diego, Oflijan, Julia, Rivera, Alicia, Romero-Fernandez, Wilber, Skieterska, Kamila, Suárez-Boomgaard, Diana, Van Craenenbroeck, Kathleen   +12 more
core   +4 more sources

Sodium is a negative allosteric regulator of the ghrelin receptor

Cell Reports, 2023
Summary: The functional properties of G protein-coupled receptors (GPCRs) are intimately associated with the different components in their cellular environment.
Guillaume Ferré, Antoniel A.S. Gomes, Maxime Louet, Marjorie Damian, Paulo M. Bisch, Olivier Saurel, Nicolas Floquet, Alain Milon, Jean-Louis Banères   +8 more
doaj  

The pentapeptide RM-131 promotes food intake and adiposity in wildtype mice but not in mice lacking the ghrelin receptor

Frontiers in Nutrition, 2015
The gastrointestinal peptide hormone ghrelin is the endogenous ligand of the growth hormone secretagogue receptor (GHSR, a.k.a. ghrelin receptor, GHR). Currently, ghrelin is the only circulating peripheral hormone with the ability to promote a positive ...
Katrin eFischer, Brian eFinan, Christoffer eClemmensen, Lex H.T. van der Ploeg, Matthias H. Tschöp, Timo D. Müller   +5 more
doaj   +1 more source