Results 71 to 80 of about 60,269 (268)
A Sleep‐Specific Midbrain Target for Sevoflurane Anesthesia
Advanced Science, 2023 Sevoflurane has been the most widely used inhaled anesthetics with a favorable recovery profile; however, the precise mechanisms underlying its anesthetic action are still not completely understood.
Tingting Yi +21 more
doaj +1 more source
Growth Hormone Secretagogue Receptor Expression in Human Pituitary Tumors1 [PDF]
The Journal of Clinical Endocrinology & Metabolism, 1998 The GH secretagogue (GHS) receptor (GHS-R) has been characterized and cloned. It is a member of a family of seven transmembrane receptors and is closely related to the neurotensin and TRH receptors. To determine the expression of this receptor in normal anterior pituitary and in 24 human pituitary adenomas, we analyzed GHS-R messenger ribonucleic acid (
Beatriz Lopes +4 more
openaire +3 more sources
The Ghrelin Receptor (Ghsr) Gene Polymorphism in Indonesian Local Chicken and Crossbreed is Associated with Carcass Traits [PDF]
, 2017 Ghrelin receptor (GHSR) gene is candidate gene for growth performance in chicken by modulating growth hormone release from the pituitary by binding to its ligand of ghrelin.
Arief, I. I. (Irma) +4 more
core +2 more sources
Effect of Ghrelin on the Cardiovascular System
Biology, 2022 Ghrelin, an n-octanoyl-modified 28-amino-acid-peptide, was first discovered in the human and rat stomach as an endogenous ligand for the growth hormone secretagogue receptor (GHS-R). Ghrelin-GHS-R1a signaling regulates feeding behavior and energy balance,
Hiroshi Hosoda
doaj +1 more source
Signal transduction mechanism of the seabream growth hormone secretagogue receptor
FEBS Letters, 2004 We have recently cloned the full‐length cDNAs of the two growth hormone secretagogue receptor (GHSR) subtypes from a teleost species, the black seabream (Acanthopagrus schlegeli) [Mol. Cell. Endocrinol. 214 (2004) 81], namely sbGHSR‐1a and sbGHSR‐1b.
Cheng, Christopher H K +3 more
openaire +5 more sources
Journal of Physiology, 2018 Presynaptic CaV2 voltage‐gated calcium channels link action potentials arriving at the presynaptic terminal to neurotransmitter release. Hence, their regulation is essential to fine tune brain circuitry.
Valentina Martínez Damonte +2 more
semanticscholar +1 more source
Children, 2021 Astragalus extract mixture HT042 is a standardized functional food granted by the Korean FDA for promoting “Children’s Height Growth”. In this study, we determined whether HT042 affects circulatory Insulin-like growth factor-1 (IGF-1) after ...
Donghun Lee +5 more
doaj +1 more source
Ghrelin accelerates synapse formation and activity development in cultured cortical networks [PDF]
, 2014 Background: While ghrelin was initially related to appetite stimulation and growth hormone secretion, it also has a neuroprotective effect in neurodegenerative diseases and regulates cognitive function. The cellular basis of those processes is related to
Feber, J. le, Stoyanova, I.I.
core +2 more sources
Impact of G protein-coupled receptor heteromers in endocrine systems. [PDF]
, 2017 The fine-tuning of endocrine homeostasis is regulated by dynamic receptor mediated processes. The superfamily of G protein-coupled receptors (GPCRs) have diverse roles in the modulation of all endocrine axes, thus understanding the mechanisms ...
Hanyaloglu, AC, Jonas, KC
core +1 more source
Recent Advances in Potential Clinical Application of Ghrelin in Obesity
Journal of Obesity, 2012 Ghrelin is the natural ligand of the growth hormone secretagogue receptor (GHS-R1a). Ghrelin is a 28 amino acid peptide possessing a unique acylation on the serine in position 3 catalyzed by ghrelin O-acyltransferase (GOAT).
Christine Delporte
doaj +1 more source