Results 71 to 80 of about 11,206 (235)

Influence of ghrelin and growth hormone deficiency on AMP-activated protein kinase and hypothalamic lipid metabolism [PDF]

, 2010
This is the peer reviewed version of the article which has been published in final form at Wiley Online Library. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for self-archiving[Abstract] Current ...
Boit, K. Da, Cordido, Fernando, Diéguez, Carlos, López, Miguel, Saha, A.K., Sangiao-Alvarellos, Susana, Varela, Luis, Vázquez, María J.   +7 more
core   +2 more sources

Ghrelin and growth hormone secretagogues, physiological and pharmacological aspect [PDF]

, 2009
[Abstract] The first “growth hormone secretagogues” (GHSs) were discovered by Bowers et al. in 1977. In 1996 the GHSs receptor (GHS-R 1a) was cloned. The endogenous ligand for this receptor, ghrelin, was not identified until 1999.
Cordido, Fernando, Isidro, María Luisa, Nemina, Rosa, Sangiao-Alvarellos, Susana   +3 more
core   +2 more sources

The role of ghrelin in anorexia nervosa [PDF]

, 2018
Ghrelin, a 28-amino acid peptide hormone expressed in X/A-like endocrine cells of the stomach, is the only known peripherally produced and centrally acting peptide that stimulates food intake and therefore attracted a lot of attention with one major ...
Schalla, Martha A., Stengel, Andreas
core   +1 more source

Dynamin Is Functionally Coupled to Insulin Granule Exocytosis [PDF]

, 2007
The insulin granule integral membrane protein marker phogrin-green fluorescent protein was co-localized with insulin in Min6B1 beta-cell secretory granules but did not undergo plasma membrane translocation following glucose stimulation.
Gaisano, HY, Halban, PA, Hou, JC, Leung, YM, Min, L, Pessin, JE, Tomas, A, Watson, RT   +7 more
core   +2 more sources

Ghrelin contributes to protection of hepatocellular injury induced by ischaemia/reperfusion [PDF]

, 2013
Background & Aims Ghrelin, a gut hormone with pleiotropic effects, may act as a protective signal in parenchymal cells. We investigated the protective effects of ghrelin on hepatocytes after ischaemia/reperfusion (I/R).
Li, Yin, Li, Ziru, Mulholland, Michael, Qin, Yan, Wang, Zhigang, Zhang, Weizhen, Zhao, Jing   +6 more
core   +1 more source

Endocrine factors in the hypothalamic regulation of food intake in females: a review of the physiological roles and interactions of ghrelin, leptin, thyroid hormones, oestrogen and insulin [PDF]

, 2011
Controlling energy homeostasis involves modulating the desire to eat and regulating energy expenditure. The controlling machinery includes a complex interplay of hormones secreted at various peripheral endocrine endpoints, such as the gastrointestinal ...
Bartha, Tibor, Frenyó, Vilmos László, Goszleth, Gréta, Győrffy, Andrea, Kiss, Dávid Sándor, Scalise, Johnson, Trudy, Somogyi, Virág, Zsarnovszky, Attila   +7 more
core   +1 more source

Slow Transit Constipation: Pathophysiological Perspectives and Management Updates

Journal of Digestive Diseases, EarlyView.
Slow transit constipation (STC) is a complex neuromuscular disorder driven by interstitial cells of Cajal (ICCs) loss and enteric neuropathy. Diagnosis relies on objective transit testing while excluding pelvic floor dysfunction. Management follows a stepwise, phenotype‐driven approach, progressing from conventional laxatives to emerging targeted ...
Athanasios Syllaios, Stavros P. Papadakos, Alexandros Ioannou, Maximos Frountzas, Dimosthenis Michelakis, Dimitrios Patsouras, Spyridon Dritsas, Manousos‐Georgios Pramateftakis, Dimitrios Schizas   +8 more
wiley   +1 more source

Acetylcholine regulates ghrelin secretion in humans [PDF]

, 2004
Ghrelin secretion has been reportedly increased by fasting and energy restriction but decreased by food intake, glucose, insulin, and somatostatin. However, its regulation is still far from clarified.
Aart Jan van der Lely, Andrea Benso, Ariyasu, Arosio, Barkan, Batterham, Bellone, Broglio, Broglio, Broglio, Broglio, Broglio, Caixas, Carlotta Gauna, Chey, Cohen, Cristina Gottero, Cummings, Cummings, Date, Date, Emanuela Arvat, Espelund, Ezio Ghigo, Fabio Broglio, Flanagan, Flavia Prodam, Ghigo, Ghigo, Gilon, Giustina, Gnanapavan, Haqq, Haqq, Kojima, Lee, Leo Hofland, Lucidi, Masuda, Mohlig, Muccioli, Muller, Nagaya, Nakagawa, Norrelund, Patel, Peter Van Koetsveld, Prodam, Rigamonti, Saad, Schaller, Shiiya, Shimada, Silvia Destefanis, Smith, Sugino, Sun, Tolle, Toshinai, Williams, Yoshihara   +60 more
core   +2 more sources

Transforming Treatment: The Impact of Bariatric Surgery on Oral Drug Absorption

Obesity Reviews, EarlyView.
ABSTRACT Obesity represents a significant threat to global public health, with an estimated 16% of adults worldwide (2022) being classified as people with obesity, with a body mass index of 30 or more. Bariatric surgery is regarded as the most effective treatment option for people with obesity, with the three main types of bariatric surgery being ...
Danielle Wigg, Andrea Edginton, Matthew D. Jones, Nikoletta Fotaki   +3 more
wiley   +1 more source

Therapeutic applications of ghrelin agonists in the treatment of gastroparesis [PDF]

, 2015
There remains an unmet need for effective pharmacologic treatments for gastroparesis. Ghrelin is the endogenous ligand for the growth hormone secretagogue receptor and has been shown to regulate energy homeostasis and exert prokinetic effects on ...
Shin, Andrea, Wo, John M.
core   +1 more source