Results 151 to 160 of about 6,248 (265)

Gasdermin E benefits CD8+T cell mediated anti-immunity through mitochondrial damage to activate cGAS-STING-interferonβ axis in colorectal cancer

Biomarker Research
Background Pyroptosis belongs to a unique type of programmed cell death among which GSDME is reported to exert anti-tumor immunity. However, the underlying mechanisms of how to boost tumor-infiltrating lymphocytes and whether it could benefit the ...
Bixian Luo, Shun Zhang, Xinbo Yu, Dan Tan, Ying Wang, Mingliang Wang   +5 more
doaj   +1 more source

A novel 3-acyl isoquinolin-1(2H)-one induces G2 phase arrest, apoptosis and GSDME-dependent pyroptosis in breast cancer

, 2022
Lei Ma, Mengyao Bian, Hui Gao, Zhi Zhou, Wei Yi   +4 more
openalex   +2 more sources

Hypericin photoactivation induces triple-negative breast cancer cells pyroptosis by targeting the ROS/CALR/Caspase-3/GSDME pathway

Journal of Advanced Research
Chen Liang, Xiao Liu, Jie Yu, Lingyun Shi, Wenchao Wei, Yalu Zhu, Maoping Feng, Tingting Tang, Dameng Li, Tao Yang, Junnian Zheng, Bo Ma, Liang Wei   +12 more
semanticscholar   +1 more source

Lipin3 deficiency aggravates cisplatin induced acute kidney injury via activating Sirt1-p21-Caspase 3-GSDME pyroptosis pathway [PDF]

Yu‐Xing Liu, Hao Huang, Fang Wang, Meifang Zhao, Jie‐Yuan Jin, Yi Dong, Qian Wang, Liang‐Liang Fan, Rong Xiang   +8 more
openalex   +1 more source

Inhibition of caspase-3-mediated GSDME-derived pyroptosis aids in noncancerous tissue protection of squamous cell carcinoma patients during cisplatin-based chemotherapy.

, 2020
Zixian Huang, Qianyu Zhang, Yan Wang, Rui Chen, Yongqiang Wang, Zhuoshan Huang, Guangming Zhou, Haigang Li, Xi Rui, Tingting Jin, Shihao Li, Yin Zhang, Zhiquan Huang   +12 more
openalex   +1 more source

Fenbendazole induces pyroptosis in breast cancer cells through HK2/caspase-3/GSDME signaling pathway [PDF]

Tingting Pan, Sha Jin, Xiaoxia Huang, Xin Xin, Qiming Xing, Wenhui Yang, Jing Dong, Lin Li   +7 more
openalex   +1 more source

TNFSF15 Inhibits Progression of Diabetic Retinopathy by Blocking Pyroptosis via Interacting with GSDME [PDF]

, 2023
Hua Li, Hongkun Zhao, Yating Dai, Yunqin Li   +3 more
openalex   +1 more source

Tables S1-S5 from Molecular Targeted Therapies Elicit Concurrent Apoptotic and GSDME-Dependent Pyroptotic Tumor Cell Death

, 2023
Haijiao Lu, Shengzhe Zhang, Jie Wu, Minjiang Chen, Mei‐Chun Cai, Yujie Fu, Wenfeng Li, Jing Wang, Xiaojing Zhao, Zhuang Yu, Pengfei Ma, Guanglei Zhuang   +11 more
openalex   +1 more source

Table1_Epithelial-Mesenchymal Transition Induces GSDME Transcriptional Activation for Inflammatory Pyroptosis.XLSX

, 2021
Chenqiang Jia (11757158), Zhuqing Zhang (674071), Jun Tang (32983), Mei-Chun Cai (491810), Jingyu Zang (11757161), Kaixuan Shi (11757164), Yunheng Sun (11757167), Jie Wu (10038), Hailei Shi (11757170), Weiping Shi (753538), Pengfei Ma (80420), Xiaojing Zhao (600854), Zhuang Yu (702576), Yujie Fu (315269), Guanglei Zhuang (3506570)   +14 more
openalex   +2 more sources

RSV temporally reprograms apoptosis and pyroptosis to balance immune evasion and replication. [PDF]

Sci Adv
Liu C, Zhou H, Li J, Meng Y, Wang J, He M, Wang W, Li Z, Qin Y, Chen M.   +9 more
europepmc   +1 more source