Results 151 to 160 of about 4,201 (162)

Gambogic Acid Induces Pyroptosis of Colorectal Cancer Cells through the GSDME-Dependent Pathway and Elicits an Antitumor Immune Response

Cancers, 2022
Rui Wei, Ling Xi, Danya Zhang
exaly  

Bnip3 mediates doxorubicin-induced cardiomyocyte pyroptosis via caspase-3/GSDME

Life Sciences, 2020
Deling Yin
exaly  

Identification of the First Single GSDME Exon 8 Structural Variants Associated with Autosomal Dominant Hearing Loss

Diagnostics, 2022
Christel Vache, Isabelle Perthus, Vasiliki Kalatzis   +2 more
exaly  

[Hearing phenotype and genotypic characteristics in GSDME-related deafness pedigrees].

Zhonghua yi xue za zhi
This retrospective study analyzed three GSDME-related deafness pedigrees diagnosed at the Chinese PLA General Hospital between January 2014 and December 2020. Through whole-exome sequencing and Sanger sequencing validation, all three pedigrees were found to carry splice-site variants causing exon 8 skipping.
X, Gao, S S, Huang, J, Zhao, J C, Xu, L M, Hu, W Q, Wang, X, Liu, J Y, Yang, D Y, Kang, Y Y, Yuan   +9 more
openaire   +1 more source

Chemotherapeutic paclitaxel and cisplatin differentially induce pyroptosis in A549 lung cancer cells via caspase-3/GSDME activation

Apoptosis: an International Journal on Programmed Cell Death, 2019
Xian-Hui He, Dong-Yun Ouyang, Bo Hu
exaly  

Miltirone induces cell death in hepatocellular carcinoma cell through GSDME-dependent pyroptosis

Acta Pharmaceutica Sinica B, 2020
Jun Chen
exaly  

Determination of the Potential Tumor-Suppressive Effects of Gsdme in a Chemically Induced and in a Genetically Modified Intestinal Cancer Mouse Model

Cancers, 2019
Guy Van Camp, Ken Op De Beeck, Erik Fransen   +2 more
exaly  

Metformin activates AMPK/SIRT1/NF-κB pathway and induces mitochondrial dysfunction to drive caspase3/GSDME-mediated cancer cell pyroptosis

Cell Cycle, 2020
Guorong Li
exaly  

The role of astrocytic GSDME in Sepsis-associated cognitive dysfunction

International Immunopharmacology
Xiaoqiang Zhao, Xinyi Wu, Qiwen Sun, Bowen Ma, Tongtong Zhang, Danjie Wang, Shenjia Gao, Yi Jiang, Ruling Shen, Wankun Chen, Jun Wang   +10 more
openaire   +1 more source

SPIROCYCLIC GSDME INHIBITORS

ZHONG QIFEI, LI ZHIHONG, WANG HEXIANG, TIAN ZHENHUA, WANG CHUNTING   +4 more
openaire   +1 more source