Results 81 to 90 of about 360,657 (334)

Contribution of mitochondrial GSH transport to matrix GSH status and colonic epithelial cell apoptosis [PDF]

Free Radical Biology and Medicine, 2008
Previously, we showed that cellular glutathione/glutathione disulfide (GSH/GSSG) play an important role in apoptotic signaling, and early studies linked mitochondrial GSH (mtGSH) loss to enhanced cytotoxicity. The current study focuses on the contribution of mitochondrial GSH transport and mitochondrial GSH/GSSG status to apoptosis initiation in a ...
Magdalena L, Circu, Cynthia, Rodriguez, Ronald, Maloney, Mary Pat, Moyer, Tak Yee, Aw   +4 more
openaire   +2 more sources

Tailoring the Properties of Functional Materials With N‐Oxides

Advanced Functional Materials, EarlyView.
The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich, Michelle Kobus, Shirin Mesgarha, Erica Moretto, Laurens Grosche, Wolfgang Maison   +5 more
wiley   +1 more source

MOTIVOS DE DESPREZO DE PLAQUETAS POR AFÉRESE COLETADAS NO BANCO DE SANGUE SÃO PAULO

Hematology, Transfusion and Cell Therapy, 2023
Objetivo: O presente estudo tem como objetivo quantificar e identificar os motivos de desprezo de plaquetas por aférese, com o intuito de avaliar se as ações estratatégicas foram eficazes na melhoria de processo e promover dimiminuição de perdas no ...
DE Rossetto, RA Bento, APC Rodrigues, AP Sessim, JA Santos, ARA Pitol   +5 more
doaj   +1 more source

The Glutathione Derivative, GSH Monoethyl Ester, May Effectively Whiten Skin but GSH Does Not [PDF]

International Journal of Molecular Sciences, 2016
Glutathione in its reduced form (GSH) is an antioxidant and also is involved in pheomelanin formation. Thus, it has been long believed that GSH has a skin whitening effect. However, its actual or direct effect is unproven. We evaluated the anti-melanogenic effects of GSH and its derivatives in vitro.
Bo Chung, So Choi, Ik Moon, Chun Park, Young-Hoon Kim, Sung Chang   +5 more
openaire   +2 more sources

Electrochemically Driven Dissipative Growth of Affinity Hydrogels for Bioresponsive Interfaces

Advanced Functional Materials, EarlyView.
Voltage pulses drive the growth and reinforcement of hydrogel films under dissipative conditions. This biocompatible strategy enables efficient integration of affinity ligands into the hydrogel matrix, enhancing the selective capture of growth factors and allowing precise temporal control over their release, making them well‐suited as adaptive ...
Roberto Baretta, Marco Frasconi
wiley   +1 more source

PERFIL DO ABASTECIMENTO DE HEMOCOMPONENTES NA REGIONAL SÃO PAULO INTERIOR E PARANÁ, PELO BANCO DE SANGUE RIBEIRÃO PRETO – GRUPO GSH

Hematology, Transfusion and Cell Therapy
Introdução: O gerenciamento de estoque de hemocomponentes é imprescindível para alcançar equilíbrio entre oferta e demanda. Para o atendimento das demandas, o Banco de Sangue Ribeirão Preto realiza em média 870 coleta de bolsas/mês entre sangue total e ...
LCM Silva, ALG Amaral, MIA Madeira, GMM Spereta, AM Sousa, EAI Rebeleto, C Zutin, TRAC Donato, M Ramos, FS Hoelz   +9 more
doaj   +1 more source

IMPLEMENTAÇÃO DO PROCESSO TRANSFUSIONAL EM PRONTUÁRIO ELETRONICO DO PACIENTE

Hematology, Transfusion and Cell Therapy, 2023
Resumo: A transfusão de hemocomponentes é de suma importância e em todo o processo transfusional existem inúmeros cuidados e procedimentos, que contribuem de forma significativa segurança transfusional do paciente.
GMM Spereta, TO Souza, YH Andrade, IC Teixeira, L Silva, TG Souza, TVG Silva, ED Campos, E Queiroz   +8 more
doaj   +1 more source

Massive Stellar Content of the Galactic Supershell GSH 305+01-24 [PDF]

, 2013
The distribution of OB stars along with that of H$\alpha$, $^{12}$CO, dust infrared emission, and neutral hydrogen is carried out in order to provide a more complete picture of interactions of the young massive stars and the observed supershell GSH 305 ...
Golev, V., Kaltcheva, N., Moran, K.
core   +1 more source

Doxorubicin‐Loaded Metal–Organic Framework for Ferroptosis‐Enhanced Chemotherapy Through Sustained Zn Release and Glutathione Peroxidase Downregulation

Advanced Healthcare Materials, EarlyView.
A robust zinc‐based metal–organic framework (ZnMOF) enables dual functions of doxorubicin delivery and sustained Zn2+ release to trigger ferroptosis‐enhnaced chemotherapy. DOX@ZnMOF effectively depletes intracellular glutathione, suppresses GPX4, and elevates reactive oxygen species, leading to efficient oxidative DNA damage and apoptosis.
Xin Ma, Chenghua Deng, Chaoyu Wang, Langston Tilman, Jinhong Li, Wenbin Lin   +5 more
wiley   +1 more source

Antioxidant status in acute stroke patients and patients at stroke risk [PDF]

, 2004
Background and Purpose: Antioxidant enzymes like copper/ zinc superoxide dismutase (SOD), catalase and gluthatione peroxidase (GSHPx) are part of intracellular protection mechanisms to overcome oxidative stress and are known to be activated in vascular ...
Haberl, R. L., Roskos, M., Streck, S., Winnefeld, K., Zimmermann, C.   +4 more
core   +1 more source