Results 31 to 40 of about 35,497 (235)

Additional file 6: of GSK-3β protects fetal oocytes from premature death via modulating TAp63 expression in mice

, 2019
Table S2. ChIP-qPCR primers. (DOCX 11 kb)
Wen, Jia, Yan, Hao, He, Meina, Zhang, Tuo, Xinyi Mu, Haibin Wang, Zhang, Hua, Guoliang Xia, Wang, Chao   +8 more
openaire   +1 more source

Gene expression profiling in mouse embryonic stem cells reveals glycogen synthase kinase-3-dependent targets of phosphatidylinositol 3-kinase and Wnt/β-catenin signaling pathways

Frontiers in Endocrinology, 2014
Glycogen synthase kinase-3 (Gsk-3) activity is an important regulator of numerous signal transduction pathways. Gsk-3 activity is the sum of two largely redundant proteins, Gsk-3α and Gsk-3β, and in general, Gsk-3 is a negative regulator of cellular ...
Colleen M Bartman, Jennifer eEgelston, Sravya eKattula, Leigh C Zeidner, Anthony eD'Ippolito, Bradley W Doble, Christopher J Phiel   +6 more
doaj   +1 more source

The Potential Role of Glycogen Synthase Kinase-3β in Neuropathy-Induced Apoptosis in Spinal Cord

Basic and Clinical Neuroscience, 2020
Introduction: Glycogen Synthase Kinase-3β (GSK-3β) participates in several signaling pathways and plays a crucial role in neurodegenerative diseases, inflammation, and neuropathic pain. The ratio of phosphorylated GSK-3β over total GSK-3β (p-GSK-3β/t-GSK-
Mina Rashvand, Samira Danyali, Homa Manaheji   +2 more
doaj  

GSK-3β at the Intersection of Neuronal Plasticity and Neurodegeneration

Neural Plasticity, 2019
In neurons, Glycogen Synthase Kinase-3β (GSK-3β) has been shown to regulate various critical processes underlying structural and functional synaptic plasticity.
Tomasz Jaworski, Ewa Banach-Kasper, Katarzyna Gralec   +2 more
doaj   +1 more source

Additional file 3: of The CXCL5/CXCR2 axis contributes to the epithelial-mesenchymal transition of nasopharyngeal carcinoma cells by activating ERK/GSK-3β/snail signalling

, 2018
Table S3. Primary antibodies used for the western blot, immunohistochemistry and immunofluorescence analyses. (DOCX 15 kb)
Qiu, Wen-Ze, Zhang, Hai-Bo, Xia, Wei-Xiong, Ke, Liang-Ru, Yang, Jing, Yu, Ya-Hui, Liang, Hu, Huang, Xin-Jun, Liu, Guo-Ying, Li, Wang-Zhong, Xiang, Yan-Qun, Kang, Tie-Bang, Guo, Xiang, Lv, Xing   +13 more
openaire   +1 more source

Glycogen Synthase Kinase-3 Beta Expression Correlates With Worse Overall Survival in Non-Small Cell Lung Cancer—A Clinicopathological Series

Frontiers in Oncology, 2021
BackgroundGlycogen Synthase Kinase-3 beta (GSK-3β) regulates diverse cell functions including metabolic activity, signaling and structural proteins. GSK-3β phosphorylates target pro-oncogenes and regulates programmed cell death-ligand 1 (PD-L1).
Marclesson Alves, Daniela de Paula Borges, Aline Kimberly, Aline Kimberly, Francisco Martins Neto, Ana Claudia Oliveira, Juliana Cordeiro de Sousa, Juliana Cordeiro de Sousa, Cleto D. Nogueira, Cleto D. Nogueira, Benedito A. Carneiro, Fabio Tavora, Fabio Tavora, Fabio Tavora   +13 more
doaj   +1 more source

Additional file 1: of The CXCL5/CXCR2 axis contributes to the epithelial-mesenchymal transition of nasopharyngeal carcinoma cells by activating ERK/GSK-3β/snail signalling

, 2018
Table S1. Median and range of the IRS for each antibody. (DOCX 13 kb)
Qiu, Wen-Ze, Zhang, Hai-Bo, Xia, Wei-Xiong, Ke, Liang-Ru, Yang, Jing, Yu, Ya-Hui, Liang, Hu, Huang, Xin-Jun, Liu, Guo-Ying, Li, Wang-Zhong, Xiang, Yan-Qun, Kang, Tie-Bang, Guo, Xiang, Lv, Xing   +13 more
openaire   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Additional file 2: of The CXCL5/CXCR2 axis contributes to the epithelial-mesenchymal transition of nasopharyngeal carcinoma cells by activating ERK/GSK-3β/snail signalling

, 2018
Table S2. Primers and vshRNAs/siRNAs used in the study. (DOCX 14 kb)
Qiu, Wen-Ze, Zhang, Hai-Bo, Xia, Wei-Xiong, Ke, Liang-Ru, Yang, Jing, Yu, Ya-Hui, Liang, Hu, Huang, Xin-Jun, Liu, Guo-Ying, Li, Wang-Zhong, Xiang, Yan-Qun, Kang, Tie-Bang, Guo, Xiang, Lv, Xing   +13 more
openaire   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source