Results 11 to 20 of about 5,937 (164)
Acta Medica, 2016 Goeckerman therapy (GT) represents an effective treatment of psoriasis including a combination of pharmaceutical grade crude coal tar (CCT) and ultraviolet irradiation (UV-R). Coal tar contains a mixture of polycyclic aromatic hydrocarbons.
Martin Beránek +6 more
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GSTM1 (Glutathione S-transferase M1) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2017 Review on GSTM1, with data on DNA, on the protein encoded, and where the gene is implicated.
Pljesa-Ercegovac, Marija, Matic, Marija
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Population-specific GSTM1 copy number variation [PDF]
Human Molecular Genetics, 2008 As one of the major glutathione conjugation enzymes, GSTM1 detoxifies a number of drugs and xenobiotics. Its expression and activity have been shown to correlate both with cancer risks and drug resistance. Through a genome-wide association study, we identified a significant association between HapMap SNP rs366631 and GSTM1 expression.
R Stephanie, Huang +8 more
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Effect of the GSTM1 genotype on the biomarkers of exposure to polycyclic aromatic hydrocarbons: Meta-analysis [PDF]
International Journal of Occupational Medicine and Environmental Health, 2017 The role of glutathione S-transferase Mu 1 (GSTM1) in the biomonitoring of polycyclic aromatic hydrocarbons (PAHs) is not clear. Our purpose has been to evaluate the influence of GSTM1 genotypes on 1-hydroxypyrene (1-OHP), deoxyribonucleic acid (DNA ...
Dandan Li +5 more
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Polymorphisms in the CYP2E1 and GSTM1 genes as possible protection factors for leprosy patients.
PLoS ONE, 2012 BackgroundThe CYP2E1 and GSTM1 genes encode metabolic enzymes that have key functions in drug modification and elimination.Methodology/principal findingsWe investigated the possible effects of CYP2E1 and GSTM1 polymorphisms in 71 leprosy patients and in ...
Pablo Pinto +6 more
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Cellular & Molecular Biology LettersBackground and aims Epidemiological evidence suggests that the phenotype of glutathione S-transferase mu 1 (GSTM1), a hepatic high-expressed phase II detoxification enzyme, is closely associated with the incidence of alcohol-related liver disease (ALD ...
Tiantian Xu +11 more
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Role of GSTM1 in resistance to lung inflammation [PDF]
Free Radical Biology and Medicine, 2012 Lung inflammation resulting from oxidant/antioxidant imbalance is a common feature of many lung diseases. In particular, the role of enzymes regulated by the NF-E2-related factor 2 (Nrf2) transcription factor has recently received increased attention.
Weidong, Wu +2 more
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Chinese Journal of Lung Cancer, 2010 Background and objective Glutathione S-transferase M1 (GSTM1) is an important phase II metabolic enzyme gene which involves metabolism of various carcinogens in human body.
Qinghua ZHOU +4 more
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Trimodal GSTT1 and GSTM1 Genotyping Assay by Real-Time PCR
The International Journal of Biological Markers, 2005 The GSTT1 and GSTM1 genes are characterized by the existence of a GST*0 null allele responsible for a lack of enzyme activity, with the respective null genotypes GSTT1*0/0 and GSTM1*0/0.
I. Girault, R. Lidereau, I. Bièche
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Frontiers in ImmunologyIntroductionCisplatin is a widely used chemotherapeutic agent prescribed to treat solid tumors. However, its clinical application is limited because of cisplatin- induced nephrotoxicity.
Peipei Li +36 more
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