Results 31 to 40 of about 16,641 (168)

ERG and GSTP1 immunostainings of PCa samples from cohort PCa2.

, 2015
Representative immunohistochemical images of PCa samples are shown that were positive for ERG and negative for GSTP1 (A), positive for both ERG and GSTP1 (B), negative for both ERG and GSTP1(C), and negative for ERG and positive for GSTP1 (D).
Burkhard Kneitz (422040), Thibault Helleputte (732986), Sofie Isebaert (757211), Pierre Gramme (732979), Mathieu Bollen (151127), Steven Joniau (422037), Karin Haustermans (757212), Aleyde Van Eynde (151110), Olivier Gevaert (365396), Annouschka Laenen (647615), Kirill Litovkin (757210), Evelyne Lerut (156765), Thomas Gevaert (739229), Martin Spahn (422036)   +13 more
core   +1 more source

Gene-environment interactions between GSTs polymorphisms and targeted epigenetic alterations in hepatocellular carcinoma following organochlorine pesticides (OCPs) exposure

Environment International, 2020
Exposure to environmental pollutant organochlorine pesticides (OCPs) and the role of tumour suppressor GSTs gene polymorphisms as well as epigenetic alterations have all been well reported in hepatocarcinogenesis.
Meiping Tian, Benhua Zhao, Francis L. Martin, Camilo L.M. Morais, Liangpo Liu, Qingyu Huang, Jie Zhang, Heqing Shen   +7 more
doaj   +1 more source

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

Advanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang, Ziyao Wang, Dongyue Zuo, Zhaowen Su, Bowen Song, Jiamin Gao, Yizhou Zhang, Ruiting Zhao, Linjie Sun, Mengdi Li, Yirui Fan, Dandan Geng, Lei Wang   +12 more
wiley   +1 more source

Polimorfismo do gene gstp1 em um estudo epidemiológico e de associação com lúpus eritematoso sistêmico e artrite reumatóide em Santa Catarina [PDF]

, 2009
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.Aproximadamente 3% da população humana sofre de alguma disfunção autoimune, na qual pode partilhar genes em comum e também um mesmo mecanismo base.
Medeiros, Mayara Delagnelo
core  

GSTP1 A>G polymorphism and chemosensitivity of osteosarcoma: A meta-analysis

Open Medicine, 2016
The association between GSTP1 A>G polymorphism and chemosensitivity of osteosarcoma is controversial according to previously published studies. We conducted this meta-analysis to further investigate the role of GSTP1 A>G genetic variation in response to ...
Fengfeng Wu, Ruqing Ye, Juntao Xu
doaj   +1 more source

The Impact of Genetic Polymorphisms on Genotoxicity (DNA Damage) Among Children Exposed to Environmental Mutagens: A Systematic Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Children, as a particularly vulnerable group, are more susceptible to these mutagens due to their developing immune systems, higher physiological vulnerability, and increased exposure through behaviors like outdoor play and hand‐to‐mouth activities. This review aims to investigate the relationship between these environmental exposures, genetic
Thiago Guedes Pinto, Daniel Vitor de Souza, Gabriel Carvalhal de Aguiar, Ana Claudia Muniz Renno, Patricia Ramos Cury, Jean Nunes dos Santos, Rogerio Aparecido Dedivitis, Daniel Araki Ribeiro   +7 more
wiley   +1 more source

Protein convertase subtilisin/Kexin type 9 inhibits hepatocellular carcinoma growth by interacting with GSTP1 and suppressing the JNK signaling pathway

Cancer Biology & Medicine, 2022
Objective: Protein convertase subtilisin/Kexin type 9 (PCSK9) has been found to be closely associated with the occurrence and development of numerous tumors.
Mingyan He, Jing Hu, Tingting Fang, Wenqing Tang, Bei Lv, Biwei Yang, Jinglin Xia   +6 more
doaj   +1 more source

Cellular Toxicity of Short‐ and Long‐Term Exposures to Polystyrene Nanoplastics and Microplastics in Fish Skin Cell Derived From Fathead Minnow (Pimephales promelas)

Journal of Applied Toxicology, EarlyView.
ABSTRACT The ubiquitous presence of microplastics and nanoplastics (MNPs) is raising concerns about their impact on the health of humans and other living organisms. Due to its tiny size, this particle can accumulate and circulate in the body after uptake, resulting in a variety of harmful outcomes on the organism, such as increased oxidative stress and
Trang Thi Nguyen, Kiyun Park, Ihn‐Sil Kwak   +2 more
wiley   +1 more source

Results of meta-analysis of GSTP1 hypermethylation.

, 2013
Results of meta-analysis of GSTP1 hypermethylation.
Josephine Aguilar (462238), Rui Chen (95310), Tong Meng (462237), Shancheng Ren (121352), Yinghao Sun (121372)   +4 more
core   +1 more source

The Preliminary Study of Pesticide Mospilan Effect on the GSTP1 Gene Methylation in Bovine Lymphocytes

Folia Veterinaria, 2019
The epigenetic mechanisms represent a dynamic, reversible and heritable manner modulating gene expression during the life cycle of an animal organism. They generate the specific epigenetic marks which constitute so-called epigenome.
Halušková J., Holečková B., Staničová J., Verebová V.   +3 more
doaj   +1 more source