Results 81 to 90 of about 16,641 (168)

GSTP1, GSTM1 and GSTT1 genetic polymorphisms and total serum GST concentration in stable male COPD

Acta Pharmaceutica, 2014
The aim of this study was to test the hypothesis that glutathione- S-transferase (GST) genotypes were associated with COPD. GSTP1, GSTM1 and GSTT1 genotypes were determined by DNA methods and GST activity spectrophotometrically in older male Caucasian ...
Žuntar Irena, Petlevski Roberta, Dodig Slavica, Popović-Grle Sanja   +3 more
doaj   +1 more source

STUDY OF ASSOCIATION OF SINGLE NUCLEOTIDE POLYMORHISMS IN GENES OF ANTIOXIDANT DEFENCE ENZYMES WITH RISK OF DEVELOPING PROSTATE CANCER IN SIBERIA

Сибирский онкологический журнал, 2016
The influence of polymorphic substitutions in antioxidant system genes (SNPsrs1050450 in the GPX1 gene, rs1695 and rs1138272 in the GSTP1gene and rs4880 in the MnSOD gene) on the risk of prostate cancer development in men living in the Siberian region of
N. A. Oskina, N. A. Ermolenko, U. A. Boyarskikh, A. F. Lazarev, V. D. Petrova, D. I. Ganov, I. S. Kunin, O. G. Tonacheva, G. I. Lifshits, M. L. Filipenko   +9 more
doaj  

Correlation and clinical significance of GSTP1 hypermethylation in hepatocellular carcinoma: a systematic review and meta-analysis

Frontiers in Genetics
BackgroundHepatocellular carcinoma (HCC) is one of the most prevalent and fatal cancers globally, with poor prognosis due to late-stage diagnosis and limited early detection methods.
Pengfei Li, Lei He, Chunxia Zhang, Chunxia Zhang, Xinyao Huang, Rong Sun, Yan Zhang, Yan Wang   +7 more
doaj   +1 more source

RETRACTED: Combined GSTM1-Null, GSTT1-Active, GSTA1 Low-Activity and GSTP1-Variant Genotype Is Associated with Increased Risk of Clear Cell Renal Cell Carcinoma.

PLoS ONE, 2016
The aim of this study was to evaluate specific glutathione S-transferase (GST) gene variants as determinants of risk in patients with clear cell renal cell carcinoma (cRCC), independently or simultaneously with established RCC risk factors, as well as to
Vesna M Coric, Tatjana P Simic, Tatjana D Pekmezovic, Gordana M Basta-Jovanovic, Ana R Savic Radojevic, Sanja M Radojevic-Skodric, Marija G Matic, Dejan P Dragicevic, Tanja M Radic, Ljiljana M Bogdanovic, Zoran M Dzamic, Marija S Pljesa-Ercegovac   +11 more
doaj   +1 more source

Inter-day and intra-day levels of salivary GSTP1-1.

, 2014
(A) Inter-day activity of GSTP1-1 (early morning recovery -Men+women). (B) Sex distribution of the salivary GSTP1-1 as average of three days (early morning recovery).
Giorgio Ricci (235478), Fabrizio Ottaviani (659868), Serena Camerini (469772), Irene Francia (659872), Raffaele Fabrini (235455), Massimo Castagnola (333882), Marco Fusetti (659867), Federica Iavarone (659871), Alessio Bocedi (235459), Francesco M. Passali (659869), Davide Topazio (659870)   +10 more
core   +1 more source

The role of GSTP1 in non-small cell lung cancer

, 2015
The unsatisfactory outcomes often encountered in the treatment of non-small cell lung cancers can be attributed to multiple drug resistance, tumour metastases, and tumour recrudescence.
王思騏, Wang, Siqi
core   +1 more source

Overexpression of long noncoding RNA LINC01419 in esophageal squamous cell carcinoma and its relation to the sensitivity to 5-fluorouracil by mediating GSTP1 methylation

Therapeutic Advances in Medical Oncology, 2019
Background: Genome-wide sequencing investigations have identified numerous long noncoding RNAs (lncRNAs) among mammals, many of which exhibit aberrant expression in cancers, including esophageal squamous cell carcinoma (ESCC).
Jian-Liang Chen, Zhi-Xiong Lin, Yun-Sheng Qin, Yu-Qi She, Yun Chen, Chen Chen, Guo-Dong Qiu, Jie-Ting Zheng, Zhong-Lin Chen, Shu-Yao Zhang   +9 more
doaj   +1 more source

GSTP1 e farmacoresistenza: sintesi e caratterizzazione di analoghi della sulfasalazina

, 2013
Le GST sono una classe enzimatica coinvolta nel metabolismo di fase 2. Negli ultimi tempi le GST, in particolare la GSTP1, hanno susictato interesse in quanto enzimi coinvolti nella farmacoresistenza.
Piubelli, Giulia
core  

GSTP1 promoter hypermethylation during breast cancer development.

, 2009
Abstract #5042 Background. Promoter hypermethylation in precursor lesions of the breast cancer may be biomarkers of cancer risk and targets for cancer chemoprevention.
M Park, J Lee, J Yoon, S Jung, M Choi, H Youn   +5 more
core   +1 more source