Results 71 to 80 of about 16,641 (168)

The GSTP1 Ile105Val polymorphism affects breast cancer cell response to cyclophosphamide.

, 2013
(A) The GSTP1 mRNA expression levels in breast cancer cell lines were detected using RT-QPCR. (B) The GSTP1 protein expression levels in breast cancer cell lines were detected using western blot.
Yue Yu (260119), Xiao-Qing Li (333801), Xu-Chen Cao (383777), Ai-Xian Tian (425583), Yu-Mei Feng (333805), Jie Ge (425582), Qing-Shan Wang (5655394), Peng-Zhou Kong (404552)   +7 more
core   +1 more source

Distribution of polymorphic genotypes of GSTP1, GSTM1 and GSTT1 and their association with primary open-angle glaucoma

Journal of Ophthalmology, 2018
Background: The role of genetic factors in the development of primary open-angle glaucoma (POAG) has been confirmed previously. Activation of oxidative stress with a reduction in the activity of glutathione S transferase (GST) family enzymes is a major ...
S.O. Rykov, A.V. Burdei, S.V. Ziablitsev, S.Iu. Mogilevskyy   +3 more
doaj   +1 more source

Predictive value of clinical toxicities of chemotherapy with fluoropyrimidines and oxaliplatin in colorectal cancer by DPYD and GSTP1 gene polymorphisms

World Journal of Surgical Oncology, 2020
Background Fluoropyrimidines and platinum are still widely used for colorectal cancer (CRC) management. Several studies have reported that mutations of dihydropyrimidine dehydrogenase (DPYD) and glutathione S-transferase pi-1 (GSTP1) polymorphisms are ...
Xunwei Deng, Jingyuan Hou, Qiaoting Deng, Zhixiong Zhong   +3 more
doaj   +1 more source

Combined effects of GSTP1 and MRP1 in melanoma drug resistance

, 2005
International audienceGlutathione-S-transferase Pi1 (GSTP1) and multidrug resistance protein 1 (MRP1) are overexpressed in melanoma, a skin cancer notoriously resistant to all current modalities of cancer therapy.
Depeille, P, Cuq, P, Evrard, A, Vian, L, P Depeille, A Evrard, P Cuq, Passagne, I, I Passagne, L Vian   +9 more
core   +1 more source

GSTP1-Mediated Inhibition of Rac1–Mineralocorticoid Receptor Signaling Underlies the Renoprotective Effect of Huangqi Tujian Decoction in Diabetic Nephropathy

Journal of Diabetes Research
Diabetic nephropathy (DN) is a leading cause of end-stage renal disease, and current therapies often fail to adequately address oxidative stress–induced podocyte injury.
Xinyuan Liu, Li Zhao, Dehai Yin, Yuanlin Piao   +3 more
doaj   +1 more source

Abstract 4002: C-terminal phosphorylation of human GSTP1 by EGFR and site-directed mutation allows JNK reactivation in glioma cells

, 2010
In malignant gliomas, the c-jun N-terminal kinase (JNK) pathway regulates tumor growth and resistance to apoptosis, and correlates with histologic grade and epidermal growth factor receptor (EGFR) tyrosine kinase expression.
Tatsunori Okamura, Francis Ali-Osman
core   +1 more source

Investigation of GSTP1 and PTEN gene polymorphisms and their association with susceptibility to colorectal cancer

Radiology and Oncology
This study investigates the association of single nucleotide polymorphism in glutathione S transferase P1 (rs1695 and rs1138272) and phosphatase and TENsin homolog (rs701848 and rs2735343) with the risk of colorectal cancer (CRC).
Durr-e-Shahwar, Zubair Hina, Raza Muhammad Kashif, Khan Zahid, Mansour Lamjed, Ali Aktar, Imran Muhammad   +6 more
doaj   +1 more source

MOESM2 of The prognostic impact of GSTM1/GSTP1 genetic variants in bladder Cancer

, 2019
Additional file 2: Figure S2. Kaplan-Meier survival curves demonstrating the overall survival of GSTP1 adjusted with HER2 status. (A) GSTP1 genotypes with HER2 gene amplification. (B) GSTP1 genotypes with HER2 gene Non-amplification.
Nada Albarakati (7538555), Asharf Dallol (7538561), Taoufik Nedjadi (6093275), Jaudah Al-Maghrabi (2620867), Dareen Khayyat (7538558)   +4 more
core   +1 more source

miR-133b controls expression of glutathione-S-transferase pi (GSTP1).

, 2012
(A) miR-133b target sites within the 3′-UTR of GSTP1 as predicted by TargetScan and MicroCosm Targets. (B) 3′-UTR targeting assay. HeLa cells were cotransfected with different combinations of miR mimics and a luciferase reporter plasmid harboring the ...
Annika Fendler (169443), Stefan H. E. Kaufmann (149315), Juan P. Patron (169439), Carsten Stephan (169480), Chloe Piso (169473), Bernd Thiede (169487), Magnus Ø. Arntzen (169464), Klaus Jung (65489), Matthias Bild (67518), Ulrike Jung (169452), Jörg Schreiber (169502), Henrik Müller (169457), Hans-Joachim Mollenkopf (157038)   +12 more
core   +1 more source

STEREOLOGIC ESTIMATION OF KI-67, CASPASE 3 AND GSTP1 POSITIVE CELLS IN PROSTATE LESIONS [PDF]

, 2011
Cell proliferation, caspase 3 and pi-form of glutathione S transferase (GSTP1) were evaluated in prostate carcinoma (PCA), proliferative inflammatory atrophy (PIA) and prostate intraepithelial neoplasia (PIN).
Rocío Martín, Vicente Gómez, Luis Santamaría, Rafael Revestido, Consuelo López, Ildefonso Ingelmo   +5 more
core   +1 more source