Results 1 to 10 of about 127,404 (181)

Oncogene ect2 is related to regulators of small GTP-binding proteins [PDF]

open access: greenNature, 1993
We have developed an efficient expression cloning system that allows rapid isolation of complementary DNAs able to induce the transformed phenotype. We searched for molecules expressed in epithelial cells and possessing transforming potential to fibroblasts, and cloned a cDNA for the normal receptor of a growth factor secreted by NIH/3T3 cells. Here we
Toru Miki   +4 more
semanticscholar   +5 more sources

Small GTP-binding protein Ran is regulated by posttranslational lysine acetylation [PDF]

open access: yesProceedings of the National Academy of Sciences, 2015
Significance The small GTPase Ran plays fundamental roles in cellular processes such as nucleo-cytoplasmic transport, mitotic spindle formation, and nuclear envelope assembly. Recently, Ran was found to be lysine acetylated, among others, in functionally important regions such as switch I and switch II.
Susanne de Boor   +9 more
semanticscholar   +3 more sources

Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family.

open access: greenProceedings of the National Academy of Sciences of the United States of America, 1995
Tsung‐Hsien Chuang   +5 more
openalex   +3 more sources

The RGK family of GTP-binding proteins: Regulators of voltage-dependent calcium channels and cytoskeleton remodeling

open access: greenCellular Signalling, 2007
Robert N. Correll   +4 more
openalex   +3 more sources

Mechanistic insights into the effect of phosphorylation on Ras conformational dynamics and its interactions with cell signaling proteins

open access: yesComputational and Structural Biotechnology Journal, 2021
Ras undergoes interconversion between the active GTP-bound state and the inactive GDP-bound state. This GTPase cycle, which controls the activities of Ras, is accelerated by Ras GTPase-activating proteins (GAPs) and guanine nucleotide exchange factors ...
Yuanhao Wang   +12 more
doaj   +1 more source

Wheat TaRab7 GTPase is part of the signaling pathway in responses to stripe rust and abiotic stimuli. [PDF]

open access: yesPLoS ONE, 2012
Small GTP-binding proteins function as regulators of specific intercellular fundamental biological processes. In this study, a small GTP-binding protein Rab7 gene, designated as TaRab7, was identified and characterized from a cDNA library of wheat leaves
Furong Liu   +8 more
doaj   +1 more source

Regulation of the Single Polar Flagellar Biogenesis

open access: yesBiomolecules, 2020
Some bacterial species, such as the marine bacterium Vibrio alginolyticus, have a single polar flagellum that allows it to swim in liquid environments.
Seiji Kojima   +2 more
doaj   +1 more source

ARHGEF3 regulates the stability of ACLY to promote the proliferation of lung cancer

open access: yesCell Death and Disease, 2022
Rho GTPases play an essential role in many cellular processes, including cell cycle progress, cell motility, invasion, migration, and transformation.
Feifei Zhou   +6 more
doaj   +1 more source

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