Results 1 to 10 of about 152,400 (305)

Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family.

Proceedings of the National Academy of Sciences of the United States of America, 1995
Tsung‐Hsien Chuang, Xuemin Xu, Vesa Kaartinen, Nora Heisterkamp, John Groffen, Gary Bokoch   +5 more
openalex   +3 more sources

The Bacillus subtilis GTP Binding Protein Obg and Regulators of the ς ^B Stress Response Transcription Factor Cofractionate with Ribosomes

Journal of Bacteriology, 2000
Janelle M. Scott, Jingliang Ju, Theresa Mitchell, W G Haldenwang   +3 more
openalex   +2 more sources

Oncogene ect2 is related to regulators of small GTP-binding proteins

Nature, 1993
Toru Miki, Cheryl L. Smith, Jason E. Long, Alessandra Eva, Timothy P. Fleming   +4 more
openalex   +3 more sources

Mechanistic insights into the effect of phosphorylation on Ras conformational dynamics and its interactions with cell signaling proteins

Computational and Structural Biotechnology Journal, 2021
Ras undergoes interconversion between the active GTP-bound state and the inactive GDP-bound state. This GTPase cycle, which controls the activities of Ras, is accelerated by Ras GTPase-activating proteins (GAPs) and guanine nucleotide exchange factors ...
Yuanhao Wang, Dong Ji, Chaoyu Lei, Yingfei Chen, Yuran Qiu, Xinyi Li, Mingyu Li, Duan Ni, Jun Pu, Jian Zhang, Qiang Fu, Yaqin Liu, Shaoyong Lu   +12 more
doaj   +1 more source

Wheat TaRab7 GTPase is part of the signaling pathway in responses to stripe rust and abiotic stimuli. [PDF]

PLoS ONE, 2012
Small GTP-binding proteins function as regulators of specific intercellular fundamental biological processes. In this study, a small GTP-binding protein Rab7 gene, designated as TaRab7, was identified and characterized from a cDNA library of wheat leaves
Furong Liu, Jun Guo, Pengfei Bai, Yinhui Duan, Xiaodong Wang, Yulin Cheng, Hao Feng, Lili Huang, Zhensheng Kang   +8 more
doaj   +1 more source

Allosteric binding sites in Rab11 for potential drug candidates. [PDF]

PLoS ONE, 2018
Rab11 is an important protein subfamily in the RabGTPase family. These proteins physiologically function as key regulators of intracellular membrane trafficking processes.
Ammu Prasanna Kumar, Suryani Lukman
doaj   +1 more source

Regulation of the Single Polar Flagellar Biogenesis

Biomolecules, 2020
Some bacterial species, such as the marine bacterium Vibrio alginolyticus, have a single polar flagellum that allows it to swim in liquid environments.
Seiji Kojima, Hiroyuki Terashima, Michio Homma   +2 more
doaj   +1 more source

ARHGEF3 regulates the stability of ACLY to promote the proliferation of lung cancer

Cell Death and Disease, 2022
Rho GTPases play an essential role in many cellular processes, including cell cycle progress, cell motility, invasion, migration, and transformation.
Feifei Zhou, Wenqian Ai, Yixing Zhang, Qifan Hu, Mingxi Gan, Jian-Bin Wang, Tianyu Han   +6 more
doaj   +1 more source

Posttranslational modification of the RHO of plants protein RACB by phosphorylation and cross-kingdom conserved ubiquitination.

PLoS ONE, 2022
Small RHO-type G-proteins act as signaling hubs and master regulators of polarity in eukaryotic cells. Their activity is tightly controlled, as defective RHO signaling leads to aberrant growth and developmental defects.
Lukas Weiß, Lana Gaelings, Tina Reiner, Julia Mergner, Bernhard Kuster, Attila Fehér, Götz Hensel, Manfred Gahrtz, Jochen Kumlehn, Stefan Engelhardt, Ralph Hückelhoven   +10 more
doaj   +1 more source

Oxytocin Downregulates the Ca_V1.2 L-Type Ca²⁺ Channel via Gi/cAMP/PKA/CREB Signaling Pathway in Cardiomyocytes

Membranes, 2021
Oxytocin (OT) and its receptor (OTR) are expressed in the heart and are involved in the physiological cardiovascular functional system. Although it is known that OT/OTR signaling is cardioprotective by reducing the inflammatory response and improving ...
Masaki Morishima, Shintaro Tahara, Yan Wang, Katsushige Ono   +3 more
doaj   +1 more source