Actin re-organization induced by Chlamydia trachomatis serovar D--evidence for a critical role of the effector protein CT166 targeting Rac. [PDF]
PLoS ONE, 2010 The intracellular bacterium Chlamydia trachomatis causes infections of urogenital tract, eyes or lungs. Alignment reveals homology of CT166, a putative effector protein of urogenital C. trachomatis serovars, with the N-terminal glucosyltransferase domain
Jessica Thalmann +7 more
doaj +1 more source
Structural Insights into HypB, a GTP-binding Protein That Regulates Metal Binding [PDF]
Journal of Biological Chemistry, 2006 HypB is a prokaryotic metal-binding guanine nucleotide-binding protein that is essential for nickel incorporation into hydrogenases. Here we solved the x-ray structure of HypB from Methanocaldococcus jannaschii. It shows that the G-domain has a different topology than the Ras-like proteins and belongs to the SIMIBI (after Signal Recognition Particle ...
Gasper, Raphael +2 more
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The small GTP-binding protein Rac is a regulator of cell death in plants [PDF]
Proceedings of the National Academy of Sciences, 1999 Cell death plays important roles in the development and defense of plants as in other multicellular organisms. Rapid production of reactive oxygen species often is associated with plant defense against pathogens, but their molecular mechanisms are not known. We introduced the constitutively active and the dominant negative forms of
T, Kawasaki +6 more
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The Rho GDI Rdi1 regulates Rho GTPases by distinct mechanisms [PDF]
, 2008 © 2008 by The American Society for Cell Biology. Under the License and Publishing Agreement, authors grant to the general public, effective two months after publication of (i.e.,.
Sakwa, I, Höfken, T, Just, U, Tiedje, C
core +1 more source
The pH dependence of polymerization and bundling by the essential bacterial cytoskeltal protein FtsZ [PDF]
, 2011 There is a growing body of evidence that bacterial cell division is an intricate coordinated process of comparable complexity to that seen in eukaryotic cells.
Raúl Pacheco-Gómez +17 more
core +2 more sources
Differential proteome analysis of pea roots at the early stages of symbiosis with nodule bacteria
Вавиловский журнал генетики и селекции, 2018 In this paper, we have analyzed changes in the proteomic spectrum of pea Pisum sativum L. roots during inoculation with rhizobial bacteria with the aim of revealing new regulators of symbiosis development. To study the changes in the proteome spectrum of
I. V. Leppyanen +3 more
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The cationic region of Rhes mediates its interactions with specific Gβ subunits [PDF]
, 2009 Ras homologue enriched in striatum (Rhes) is a small monomeric G protein which functions in a variety of cellular processes, including attenuation of G protein-coupled receptor (GPCR)signalling.
Ladds, Graham +3 more
core +1 more source
Regulation of the small GTP‐binding protein Rho by cell adhesion and the cytoskeleton [PDF]
The EMBO Journal, 1999 Soluble factors from serum such as lysophosphatidic acid (LPA) are thought to activate the small GTP-binding protein Rho based on their ability to induce actin stress fibers and focal adhesions in a Rho-dependent manner. Cell adhesion to extracellular matrices (ECM) has also been proposed to activate Rho, but this point has been controversial due to ...
X D, Ren, W B, Kiosses, M A, Schwartz
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Regulators of G protein signalling proteins in the human myometrium [PDF]
, 2009 The contractile state of the human myometrium is controlled by extracellular signals that promote relaxation or contraction. Many of these signals function through G proteincoupled receptors at the cell surface, stimulating heterotrimeric G proteins and ...
Ladds, Graham +4 more
core +1 more source
PLoS ONE, 2019 Regulators of G Protein Signaling (RGS proteins) inhibit G protein-coupled receptor (GPCR) signaling by accelerating the GTP hydrolysis rate of activated Gα subunits.
Adam B Schroer +5 more
doaj +1 more source