Results 41 to 50 of about 4,439,363 (293)

Phytochrome regulates GTP‐binding protein activity in the envelope of pea nuclei [PDF]

The Plant Journal, 1993
Three GTP‐binding proteins with apparent molecular masses of 27, 28 and 30 kDa have been detected in isolated nuclei of etiolated pea plumules. After LDS‐PAGE and transfer to nitrocellulose these proteins bind [32p]GTP in the presence of excess ATP, suggesting that they are monomeric G proteins.
G B, Clark, A R, Memon, , Tong C-G, G A, Thompson, S J, Roux   +4 more
openaire   +2 more sources

Recruitment of AP-1 clathrin adaptors to liposomal membranes [PDF]

, 2004
Protein and membrane traffic between organelles within the endocytic and exocytic pathway is mediated most prominently by coated vesicles. These vesicles are formed by the assembly of cytosolic coat proteins onto the donor membrane, which deform it into ...
Meyer, Daniel Markus
core   +1 more source

Small GTP-binding protein Ran is regulated by posttranslational lysine acetylation [PDF]

Proceedings of the National Academy of Sciences, 2015
Significance The small GTPase Ran plays fundamental roles in cellular processes such as nucleo-cytoplasmic transport, mitotic spindle formation, and nuclear envelope assembly. Recently, Ran was found to be lysine acetylated, among others, in functionally important regions such as switch I and switch II.
Susanne, de Boor, Philipp, Knyphausen, Nora, Kuhlmann, Sarah, Wroblowski, Julian, Brenig, Lukas, Scislowski, Linda, Baldus, Hendrik, Nolte, Marcus, Krüger, Michael, Lammers   +9 more
openaire   +2 more sources

Guanosine nucleotides regulate B2 kinin receptor affinity of agonists but not of antagonists: Discussion of a model proposing receptor precoupling to G protein [PDF]

, 2000
The effect of nucleotides on binding of the B2 kinin (BK) receptor agonist {[}H-3]BK and the antagonist {[}H-3]NPC17731 to particulate fractions of human foreskin fibroblasts was studied.
Er Faussner, Faussner, Alexander, Adelbert A. Roscher, Roscher, Adelbert A.   +3 more
core   +1 more source

Characterisation of Bombyx mori odorant-binding proteins reveals that a general odorant-binding protein discriminates between sex pheromone components [PDF]

, 2009
In many insect species, odorant-binding proteins (OBPs) are thought to be responsible for the transport of pheromones and other semiochemicals across the sensillum lymph to the olfactory receptors (ORs) within the antennal sensilla.
Field, L.M., Pickett, J. A., Dufour, S. G. L., Zhou, J.J., Keep, N. H., Dufour, Samuel, Field, Linda M., He, X., Hooper, A.M., Hooper, A. M., Pickett, John A., Pickett, J.A., He, Xiaoli, Dufour, S., Field, L. M., Keep, Nicholas H., Robertson, G., Robertson, Giles, Zhou, J-J., Hooper, Antony M., Zhou, Jing-Jiang   +20 more
core   +1 more source

The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondii [PDF]

, 2011
Background: The interferon-inducible immunity-related GTPases (IRG proteins/p47 GTPases) are a distinctive family of GTPases that function as powerful cell-autonomous resistance factors.
Khaminets, Aliaksandr, Wolf, Eva, Vopper, G., Pawlowski, Nikolaus, Schmidt, Andreas, Lange Rita, Aliaksandr Khaminets, Nikolaus Pawlowski, Papic, Natasa, Gabriela Vopper, Papic Natasa, Pawlowski, N., Uthaiah, Revathy C., Natasa Papic, Howard, J. C., Hunn, Julia P., Uthaiah, R. C., Andreas Schmidt, Eva Wolf, Hunn, J., Vopper, Gabriela, Julia P Hunn, Schmidt Andreas, Rita Lange, Sascha Martens, Uthaiah, Revathy Chottekalapanda, Martens Sascha, Wolf, E., Jonathan C Howard, Lange, Rita, Martens, Sascha, Papic, N., Wolf Eva, Lange, R., Hunn Julia P, Khaminets Aliaksandr, Howard, Jonathan C., Howard, J., Howard Jonathan C, Schmidt, A., Uthaiah Revathy C, Khaminets, A., Pawlowski Nikolaus, Revathy C Uthaiah, Uthaiah, R., Martens, S., Hunn, J. P., Hunn, Julia, Vopper Gabriela   +48 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Substrate binding disrupts dimerization and induces nucleotide exchange of the chloroplast GTPase Toc33

, 2011
GTPases act as molecular switches to control many cellular processes, including signalling, protein translation and targeting. Switch activity can be regulated by external effector proteins or intrinsic properties, such as dimerization.
Ivo Tews, Patrick Koenig, Danny J. Schnell, Tews, Ivo, Sinning, Irmgard, Enrico Schleiff, Oreb, Mislav, Schnell, Danny, Koenig, Patrick, Mislav Oreb, Maik S. Sommer, Sommer, Maik S, Wang, Fei, Schnell, Danny J., Schleiff, Enrico, Irmgard Sinning, Sommer, Maik S., Fei Wang, Anja Höfle, Höfle, Anja   +19 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Pathogenic single nucleotide polymorphisms in RhoA gene: Insights into structural and functional impacts on RhoA-PLD1 interaction through molecular dynamics simulation

Current Research in Structural Biology
Molecular switches serve as key regulators of biological systems by acting as one of the crucial driving forces in the initiation of signal transduction pathway cascades.
Mahbub Hasan, Md. Nayem Sarker, Tazkia Jabin, Saifuddin Sarker, Shamim Ahmed, Mohammad Abdullah-Al-Shoeb, Tanvir Hossain   +6 more
doaj   +1 more source