Rabs, Rips, FIPs, and Endocytic Membrane Traffic
Rab GTPases, proteins belonging to the Ras-like small GTP-binding protein superfamily, have emerged as master regulators of cellular membrane transport.
Rytis Prekeris
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The GDP-GTP exchange factor collybistin: an essential determinant of neuronal gephyrin clustering [PDF]
Glycine receptors (GlyRs) and specific subtypes of GABA(A) receptors are clustered at synapses by the multidomain protein gephyrin, which in turn is translocated to the cell membrane by the GDP-GTP exchange factor collybistin.
Ward, H +53 more
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In the crenarchaeon Sulfolobus acidocaldarius, the archaellum, a type-IV pilus like motility structure, is synthesized in response to nutrient starvation. Synthesis of components of the archaellum is controlled by the archaellum regulatory network (arn).
Xing Ye +10 more
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Novel split-luciferase-based genetically encoded biosensors for noninvasive visualization of Rho GTPases. [PDF]
Rho family GTPases are critical regulators of many important cellular processes and the dysregulation of their activities is implicated in a variety of human diseases including oncogenesis and propagation of malignancy.
Weibing Leng +10 more
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The individual and common repertoire of DNA-binding transcriptional regulators of Corynebacterium glutamicum, Corynebacterium efficiens, Corynebacterium diphtheriae and Corynebacterium jeikeium deduced from the complete genome sequences [PDF]
Brune I, Brinkrolf K, Kalinowski J, Pühler A, Tauch A. The individual and common repertoire of DNA-binding transcriptional regulators of Corynebacterium glutamicum, Corynebacterium efficiens, Corynebacterium diphtheriae and Corynebacterium jeikeium ...
Brune, Iris +4 more
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Borrelia valaisiana resist complement-mediated killing independently of the recruitment of immune regulators and inactivation of complement components [PDF]
Spirochetes belonging to the Borrelia (B.) burgdorferi sensu lato complex differ in their resistance to complement-mediated killing, particularly in regard to human serum.
Christine Skerka +24 more
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Allosteric binding sites in Rab11 for potential drug candidates.
Rab11 is an important protein subfamily in the RabGTPase family. These proteins physiologically function as key regulators of intracellular membrane trafficking processes.
Ammu Prasanna Kumar, Suryani Lukman
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Function and regulation of Rnd proteins in cortical projection neuron migration
The mammalian cerebral cortex contains a high variety of neuronal subtypes that acquire precise spatial locations and form long or short-range connections to establish functional neuronal circuits.
Roberta eAzzarelli +3 more
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High throughput transcriptome profiling of lithium stimulated human mesenchymal stem cells reveals priming towards osteoblastic lineage. [PDF]
Human mesenchymal stem cells (hMSCs) present in the bone marrow are the precursors of osteoblasts, chondrocytes and adipocytes, and hold tremendous potential for osteoregenerative therapy.
Neeraj Kumar Satija +4 more
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Backbone dynamics of complement control protein (CCP) modules reveals mobility in binding surfaces [PDF]
The regulators of complement activation (RCA) are critical to health and disease because their role is to ensure that a complement-mediated immune response to infection is proportionate and targeted.
Krystyna Bromek +19 more
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