Results 191 to 200 of about 153,070 (268)

Small GTP-binding Proteins—A New Family of Biologic Regulators

American Journal of Respiratory Cell and Molecular Biology, 1992
Alan Hall
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Developmentally regulated GTP-binding protein-2 regulates adipocyte differentiation

Biochemical and Biophysical Research Communications, 2021
Developmentally regulated GTP-binding protein 2 (DRG2) participates in the regulation of proliferation and differentiation of multiple cells. However, whether DRG2 regulates adipocyte differentiation and related metabolic control remains elusive. This study revealed increases in body weight and adiposity in DRG2 transgenic (Tg) mice overexpressing DRG2.
Byong Seo Park, Hye Li Im, Nal Ae Yoon, Thai Hien Tu, Jeong Woo Park, Jae Geun Kim, Byung Ju Lee   +6 more
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Common Properties of Receptors Coupled to GTP Binding Regulator Proteins

, 1989
A number of membrane receptors coupled to GTP binding regulatory proteins have recently been shown to share structural propertie at the level both of the genes and of the corresponding proteins (Fig. 1 and 2). By comparing results obtained for α2-, β1- and β2-adrenergic catecholamine receptors, M1 to M5 muscarinic acetylcholine receptors as well as ...
Laurent J. Emorine, Stéfano Marullo, Malène Sutren, C Delavier, Y. Eshdat, Graça Raposo, A. Donny Strosberg   +6 more
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Regulation of small GTP-binding proteins by insulin

Biochemical Society Transactions, 2006
Several members of the extensive family of small GTP-binding proteins are regulated by insulin, and have been implicated in insulin action on glucose uptake. These proteins are themselves negatively regulated by a series of specific GAPs (GTPase-activating proteins).
G I, Welsh, I, Hers, M, Wherlock, J M, Tavaré   +3 more
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Tumour suppressors and the regulation of GTP-binding protein activity

Trends in Cell Biology, 1993
GTP-binding proteins regulate a wide variety of intracellular signalling pathways in eukaryotic cells. The Ras GTP-binding proteins have received a great deal of attention since they were found to be modified by amino acid substitutions in a large number of cancers.
I, Rey, A, Hall
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DRG: A novel developmentally regulated GTP-binding protein

Biochemical and Biophysical Research Communications, 1992
Using a subtraction cloning approach we had previously isolated a series of murine cDNA clones representing the genes predominantly expressed in the embryonic brain and down-regulated during development. We now report that one of these cDNA clones encodes a novel type of GTP-binding protein.
T, Sazuka, Y, Tomooka, Y, Ikawa, M, Noda, S, Kumar   +4 more
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SOCS: negative regulators of cytokine signaling for immune tolerance.

International Immunology, 2021
Cytokines are important intercellular communication tools for immunity. Many cytokines promote gene transcription and proliferation through the JAK/STAT (Janus kinase / signal transducers and activators of transcription) and the Ras/ERK (GDP/GTP-binding ...
A. Yoshimura, Minako Ito, S. Mise-Omata, M. Ando   +3 more
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Regulation of vesicular transport by GTP-binding proteins

Current Opinion in Nephrology and Hypertension, 1995
Intracellular protein trafficking occurs in a series of transport vesicles. Vesicle trafficking is regulated both by heterotrimeric and monomeric GTP-binding proteins (G proteins). Recent studies have explored effector systems used by heterotrimeric G proteins and by monomeric ADP-ribosylation factor G proteins for regulation of vesicle budding.
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Lipid transport protein ORP2A promotes glucose signaling by facilitating RGS1 degradation.

Plant Physiology, 2023
Heterotrimeric GTP-binding proteins (G proteins) are a group of regulators essential for signal transmission into cells. Regulator of G-protein signaling 1 (AtRGS1) possesses intrinsic GTPase-accelerating protein (GAP) activity and could suppress G ...
Qian Yu, Wenjiao Zou, Kui Liu, Jialu Sun, Yanru Chao, Mengyao Sun, Qianqian Zhang, Xiaodong Wang, Xiaofei Wang, L. Ge   +9 more
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Distribution and Regulation of RAB3C, a Small Molecular Weight GTP-Binding Protein

Biochemical and Biophysical Research Communications, 1994
We have investigated the expression and regulation of rab3C in rat tissues and rat pheochromocytoma PC12 cells by using a polyclonal antibody that specifically recognizes this protein. Rab3C was expressed in the neuroendocrine systems, as is its highly homologous family member, rab3A.
Y C, Su, L S, Kao, Y Y, Chu, Y, Liang, M H, Tsai, Y, Chern   +5 more
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