Results 191 to 200 of about 81,307 (285)

Vesicular transport in the autophagic route: RAB GTPases as pivotal regulators of autophagy. [PDF]

Biochem J
Abba R, Colombo MI.
europepmc   +1 more source

Disabling posttranscriptional regulation of AGO2 results in enhanced viral resistance

New Phytologist, EarlyView.
Márta Ludman, Károly Fátyol
wiley   +1 more source

Anti‐Biofilm Properties of Polyurethane Biomaterials Tethered With Small Molecules via Polyethylene Glycol Linker

Journal of Biomedical Materials Research Part A, Volume 114, Issue 4, April 2026.
Interfering with nucleotide signaling pathways using small molecules represents a promising strategy to disrupt biofilm formation on biomaterial surfaces. This study reported a new approach for tethering small molecules onto polyurethane surfaces using a PEG long linker.
Jiale Liu, Chen Chen, Jennifer L. Booth, Matthew Lanza, Dongxiao Sun, Harry R. Allcock, Christopher A. Siedlecki, Li‐Chong Xu   +7 more
wiley   +1 more source

A flow equilibrium model controlling cytoplasmic transition metal cation pools and preventing mis-metalation as exemplified for zinc homeostasis. [PDF]

J Bacteriol
Nies DH.
europepmc   +1 more source

Deficient Cardiolipin Remodelling Alters Muscle Fibre Composition and Neuromuscular Connectivity in Barth Syndrome

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background Barth syndrome (BTHS) is a rare X‐linked mitochondrial disorder caused by mutations in the TAFAZZIN gene, which disrupts cardiolipin (CL) remodelling and mitochondrial function. While cardiac manifestations of BTHS are well characterized in male patients, the mechanisms underlying skeletal muscle weakness and fatigability are poorly
Catalina Matias, Paige L. Snider, Elizabeth A. Sierra Potchanant, Joshua R. Huot, Rahul Raghav, Michael T. Chin, Simon J. Conway, Jeffrey J. Brault   +7 more
wiley   +1 more source

EZR-PLC and RhoGTPases interactions in osteosarcoma pathogenesis and metastatic process [PDF]

, 2014
LEOPIZZI, MARTINA
core  

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

MedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi, Shahin Ramazi, Mona Darvazi, Sepideh Yoosefi, Melika Abbasi, Shirin Farsad   +5 more
wiley   +1 more source

Prospects and advances of PROTAC in the treatment of hematologic malignancies. [PDF]

Exp Hematol Oncol
Wang X, Zhang M, Mei H.
europepmc   +1 more source

Hydroxyl radical footprinting modification reveals an intradomain communication pathway in EFL1 disrupted by a Shwachman‐Diamond syndrome‐associated mutation

Protein Science, Volume 35, Issue 4, April 2026.
Abstract Shwachman‐Diamond syndrome (SDS) is a rare genetic disorder characterized by pancreatic insufficiency and neutropenia. While most cases are linked to mutations in the SBDS gene, some involve mutations in the GTPase EFL1. This protein works with SBDS to release the anti‐association factor eIF6 from the 60S ribosomal subunit during ribosome ...
Jonathan A. Zúñiga‐Domínguez, Rohit Jain, Martín González‐Andrade, Erik R. Farquhar, Mark R. Chance, Abril Gijsbers, Nuria Sánchez‐Puig   +6 more
wiley   +1 more source

IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review). [PDF]

Int J Mol Med
Zhu H, Wang H, Li X, Zhang W, Wang Y, Tan Q, Ying D, Shi Z, Song J.   +8 more
europepmc   +1 more source