Results 191 to 200 of about 154,453 (348)

Signal transduction through the GTP-binding proteins Rac and Rho

Journal of Cell Science, 1994
A. Ridley
semanticscholar   +1 more source

EHD4 and ASAP2 are critical negative regulators of the claudin‐5‐based endothelial barrier

The FEBS Journal, EarlyView.
Cell‐surface CLDN‐5 protein levels can be evaluated using a probe that can bind to the extracellular domains of CLDN‐5. A probe derived from Clostridium perfringens enterotoxin allows us to isolate cells with high CLDN‐5 protein levels from a knockout cell library.
Yosuke Hashimoto, Gergő Porkoláb, Natalie Hudson, Jeffrey O'Callaghan, Nicole Hanley, Conor Delaney, Mária A. Deli, Peter Westenskow, Matthew Campbell   +8 more
wiley   +1 more source

Translational control in plants: from basic mechanisms to environmental and developmental responses. [PDF]

Plant J
Lyons J, Merchante C, Stepanova AN, Alonso JM.   +3 more
europepmc   +1 more source

LAT1/SLC7A5‐mediated amino acid uptake is regulated by redox signals triggered by formyl‐peptide receptor 2

The FEBS Journal, EarlyView.
FPR2 activation mediates NOX‐dependent LAT1 expression and, in turn, promotes mTORC1 signaling. Upon stimulation with WKYMVm, the FPR2‐NOX2‐ROS axis upregulates LAT1 via increased c‐Myc phosphorylation and decreased miR‐126. Additionally, it promotes CD98 translocation to the plasma membrane.
Myrhiam Cassese, Chiara Brignola, Stefano Marrone, Gabriella Esposito, Rosario Ammendola, Fabio Cattaneo   +5 more
wiley   +1 more source

FtsZ phosphorylation modulates tail-core binding to tune cell division in Bacillus subtilis. [PDF]

PLoS One
Mallard WJ, Pham VV.
europepmc   +1 more source

Long‐term remission of type B insulin resistance syndrome with immunotherapy: A case report

Journal of Diabetes Investigation, EarlyView.
ABSTRACT We report long‐term remission in a patient with type B insulin resistance achieved with a combination of immunotherapies. A 55‐year‐old Japanese man presented with nocturnal hypoglycemia and cytopenia. He also had postprandial hyperglycemia due to severe insulin resistance, which was difficult to manage using high‐dose insulin and recombinant ...
Erika Egawa, Rei Karasawa, Yuka Kageyama, Kazuhiko Takaya   +3 more
wiley   +1 more source

Direct crosstalk between GPCRs and ion channels via G proteins. [PDF]

Exp Mol Med
Kim SH, Kim J, So I, Lee HH.
europepmc   +1 more source

Differential Protein Dynamics of Regulators of G-Protein Signaling: Role in Specificity of Small-Molecule Inhibitors.

Journal of the American Chemical Society, 2018
Vincent S. Shaw, Hossein Mohammadiarani, Harish Vashisth, R. Neubig   +3 more
semanticscholar   +1 more source

scRNA‐Seq reveals anti‐lymphoma immune responses in mogamulizumab‐associated skin eruptions

Journal of the European Academy of Dermatology and Venereology, EarlyView.
CCR4 was expressed in malignant clones and regulatory T cells in untreated CTCL, that were decreased in MAR. Malignant clones in MAR showed a silenced phenotype with decreases in central memory markers SELL and CCR7, and GTP‐binding member GIMAP7 and upregulation of MMP2 inhibitor TIMP2 and tumour suppressor gene RUNX3.
Shannon Meledathu, Agata Kurowski, Malini P. Naidu, Jonas Adalsteinsson, Shane A. Meehan, Natalia Alkon, Lauren R. Port, Sumanth Chennareddy, Emry R. Cohenour, Grace Christensen, Jonah Shulman, Nicholas Gulati, Constanze Jonak, Patrick M. Brunner   +13 more
wiley   +1 more source

Phosphorylation at S1288 of leukemia associated RhoGEF (LARG/ARHGEF12) induces plasma membrane localization and promotes binding and activation of RhoA. [PDF]

J Biol Chem
Yang WS, Ghanem NZ, Scahill SD, Caliva MJ, Röttig H, Fitz A, Matter ML, Ramos JW.   +7 more
europepmc   +1 more source