Translational control in plants: from basic mechanisms to environmental and developmental responses. [PDF]
Lyons J +3 more
europepmc +1 more source
Structural insights into SetA-mediated Rab1 glucosylation and PI3P-guided localization during early <i>Legionella</i> infection. [PDF]
Im HN +11 more
europepmc +1 more source
Engineered interfaces in Rac1 and Cdc42 biosensors enhance sensitivity and reduce cell perturbation. [PDF]
Marston DJ +10 more
europepmc +1 more source
The cytokinesis regulator RacGAP1 is a Rac1-specific GAP on membranes. [PDF]
Dubois P +5 more
europepmc +1 more source
Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
FtsZ phosphorylation modulates tail-core binding to tune cell division in Bacillus subtilis. [PDF]
Mallard WJ, Pham VV.
europepmc +1 more source
A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun +11 more
wiley +1 more source
The RhoG-Binding Domain of ELMO1 Rescues the PTENopathy-like Phenotype in Oligodendroglial FBD-102b Cells. [PDF]
Takahashi M +4 more
europepmc +1 more source
GNL3 is a novel AR coregulator with dual coactivator and corepressor functions in prostate cancer (PCa). Our study uncovers a previously unrecognized mechanism by which the AR transcriptional complex integrates oncogenic signaling and immune suppression.
Cuiting Zhang +12 more
wiley +1 more source
Overexpression generates aberrant distribution of endocytic regulators - the case of the Rab11/LAMP1 compartment. [PDF]
Hornfeck S, Trofimenko E, Widmann C.
europepmc +1 more source

