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Integrin-mediated signalling: regulation by protein tyrosine kinases and small GTP-binding proteins
Current Opinion in Cell Biology, 1996Integrin signalling requires the activation of protein tyrosine kinases and members of the Rho family of small GTP-binding proteins. Recent evidence shows that coordinated regulation of these signalling molecules is central to the control of cell adhesion, formation of the actin cytoskeleton and activation of intracellular signalling cascades.
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Highlight: GTP Binding Proteins Central Regulators in Cell Biology
Biological Chemistry, 2000Wittinghofer, A., Gierschik, P.
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The GTP-binding protein, Go, regulates neuronal calcium channels.
Nature, 1987In neuronal cells, opioid peptides and opiates inhibit neurotransmitter release, which is a calcium-dependent process. They also inhibit adenylyl cyclase, presumably via the membrane signal-transducing component, Gi, a guanine nucleotide-binding protein (G-protein). No causal relationship between these two events has yet been demonstrated.
J, Hescheler +3 more
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Regulation of Rod GTP Binding Protein by Guanine Nucleotides1
The Journal of Biochemistry, 1984Hitoshi SHICHI, Robert L. SOMERS
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Small GTP-Binding Proteins and the Regulation of the Actin Cytoskeleton
Annual Review of Cell Biology, 1994openaire +2 more sources
Regulation of calcium signalling by the small GTP-binding proteins Ras and Rac1
Advances in Enzyme Regulation, 2007Karl, Maly +6 more
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ARF family G proteins and their regulators: roles in membrane transport, development and disease
Nature Reviews Molecular Cell Biology, 2011Catherine L Jackson +2 more
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Small GTP-binding Proteins—A New Family of Biologic Regulators
American Journal of Respiratory Cell and Molecular Biology, 1992openaire +2 more sources